Adalat CC

DRUG DESCRIPTION

Adalat® CC (nifedipine) is an extended release tablet dosage form of the calcium channel blocker nifedipine. Nifedipine is 3,5-pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-dimethyl ester, C17H18N2O6, and has the structural formula:

ADALAT® CC (nifedipine) Structural Formula Illustration

Nifedipine is a yellow crystalline substance, practically insoluble in water but soluble in ethanol. It has a molecular weight of 346.3. Adalat CC (nifedipine) tablets consist of an external coat and an internal core. Both contain nifedipine, the coat as a slow release formulation and the core as a fast release formulation. Adalat CC tablets contain either: 30, 60, or 90 mg of nifedipine for once-a-day oral administration.

Inert ingredients in the formulation are: hydroxypropylcellulose, lactose, corn starch, crospovidone, microcrystalline cellulose, silicon dioxide, and magnesium stearate. The inert ingredients in the film coating for Adalat CC (nifedipine) 30 and 60 are: hypromellose, polyethylene glycol, ferric oxide, and titanium dioxide. The inert ingredients in the film coating for Adalat CC (nifedipine) 90 are: hypromellose, polyethylene glycol and ferric oxide.

What are the possible side effects of nifedipine (Adalat CC, Procardia, Procardia XL)?

If you experience any of the following serious side effects, stop taking nifedipine and contact your doctor immediately or seek emergency medical treatment:

  • an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
  • unusually fast or slow heartbeats;
  • severe dizziness or fainting;
  • psychosis;
  • yellowing of the skin or eyes (jaundice); or
  • swelling of the legs or ankles.

Other, less...

Read All Potential Side Effects and See Pictures of Adalat CC »

What are the precautions when taking nifedipine (Adalat CC)?

Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or to other calcium channel blockers (e.g., felodipine, amlodipine); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: heart problems (e.g., congestive heart failure, aortic stenosis), liver problems, kidney problems, a certain metabolic disorder (porphyria).

Before having surgery, tell your doctor or dentist that you are taking this medication.

This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you...

Read All Potential Precautions of Adalat CC »


Adalat CC Consumer (continued)

SIDE EFFECTS: Headache, dizziness, nausea, flushing, constipation, leg/muscle cramps, or sexual problems may occur. To reduce dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately if any of these unlikely but serious side effects occur: swelling of the ankles/feet, shortness of breath, unusual weakness/tiredness.

Tell your doctor immediately if any of these rare but very serious side effects occur: fast/slow/irregular heartbeat, fainting, mental/mood changes, swollen/tender gums, vision changes.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS: Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or to other calcium channel blockers (e.g., felodipine, amlodipine); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: heart problems (e.g., congestive heart failure, aortic stenosis), liver problems, kidney problems, a certain metabolic disorder (porphyria).

Before having surgery, tell your doctor or dentist that you are taking this medication.

This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

Nifedipine passes into breast milk. While there have been no reports of harm to nursing infants, consult your doctor before breast-feeding.


Adalat CC Patient Information Including Side Effects

Brand Names: Adalat CC, Procardia, Procardia XL

Generic Name: nifedipine (Pronunciation: nye FEH dih peen)

  • What is nifedipine (Adalat CC)?
  • What are the possible side effects of nifedipine (Adalat CC)?
  • What is the most important information I should know about nifedipine (Adalat CC)?
  • What should I discuss with my healthcare provider before taking nifedipine (Adalat CC)?
  • How should I take nifedipine (Adalat CC)?
  • What happens if I miss a dose (Adalat CC)?
  • What happens if I overdose (Adalat CC)?
  • What should I avoid while taking nifedipine (Adalat CC)?
  • What other drugs will affect nifedipine (Adalat CC)?
  • Where can I get more information?

What is nifedipine (Adalat CC)?

Nifedipine is in a class of drugs called calcium channel blockers. Nifedipine relaxes (widens) your blood vessels (veins and arteries), which makes it easier for the heart to pump and reduces its workload.

Nifedipine is used to lower hypertension (high blood pressure) and to treat angina (chest pain).

Nifedipine may also be used for purposes other than those listed in this medication guide.

What are the possible side effects of nifedipine (Adalat CC)?

If you experience any of the following serious side effects, stop taking nifedipine and contact your doctor immediately or seek emergency medical treatment:

  • an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
  • unusually fast or slow heartbeats;
  • severe dizziness or fainting;
  • psychosis;
  • yellowing of the skin or eyes (jaundice); or
  • swelling of the legs or ankles.

Other, less serious side effects may be more likely to occur. Continue to take nifedipine and talk to your doctor if you experience

  • headache, fatigue, or tiredness;
  • flushing;
  • insomnia;
  • vivid or abnormal dreams;
  • nausea or constipation; or
  • increased urination.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about nifedipine (Adalat CC)?

Do not stop taking nifedipine without first talking to your doctor, even if you begin to feel better. If you stop taking the medication, your condition could become worse.

Do not crush, chew, or break any form of nifedipine. Swallow the pills whole.

Do not consume grapefruit or grapefruit juice during treatment with nifedipine. Nifedipine can interact with grapefruit and grapefruit juice, and the interaction may have dangerous effects. You should discuss the use of grapefruit and grapefruit juice with your doctor.

Related Drug Centers
  • Procardia
  • Adalat


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