Zovirax Ointment

DRUG DESCRIPTION

ZOVIRAX is the brand name for acyclovir, a synthetic nucleoside analogue active against herpes viruses. ZOVIRAX Ointment (acyclovir ointment) 5% is a formulation for topical administration. Each gram of ZOVIRAX Ointment 5% contains 50 mg of acyclovir in a polyethylene glycol (PEG) base.

Acyclovir is a white, crystalline powder with the molecular formula C8H11N5O3 and a molecular weight of 225. The maximum solubility in water at 37°C is 2.5 mg/mL. The pka's of acyclovir are 2.27 and 9.25.

The chemical name of acyclovir is 2-amino-1,9-dihydro-9- [(2-hydroxyethoxy)methyl]-6H-purin-6-one; it has the following structural formula:

ZOVIRAX® (acyclovir) Structural Formula Illustration

What are the possible side effects of acyclovir topical (Zovirax Topical)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Less serious side effects are more likely to occur, such as itching, swelling, or pain where the medicine is applied.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at...

Read All Potential Side Effects and See Pictures of Zovirax Ointment »

What are the precautions when taking acyclovir ointment (Zovirax Ointment)?

Before using acyclovir, tell your doctor or pharmacist if you are allergic to it; or to valacyclovir; or if you have any other allergies. This product may contain inactive ingredients (such as polyethylene glycol), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Cold sores can spread easily. Avoid close physical contact with others (such as kissing) during an outbreak until the cold sores have completely healed. Try not to touch the cold sore. If you do, wash your hands...

Read All Potential Precautions of Zovirax Ointment »


Zovirax Ointment Consumer (continued)

SIDE EFFECTS: This medication may cause mild, temporary burning or stinging when you apply it. If either of these effects persists or worsens, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS: Before using acyclovir, tell your doctor or pharmacist if you are allergic to it; or to valacyclovir; or if you have any other allergies. This product may contain inactive ingredients (such as polyethylene glycol), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Cold sores can spread easily. Avoid close physical contact with others (such as kissing) during an outbreak until the cold sores have completely healed. Try not to touch the cold sore. If you do, wash your hands afterward.

To lower the chance of giving genital herpes to your partner, do not have sexual contact during an outbreak or if you have symptoms. You can spread genital herpes even if you do not have symptoms. Therefore, always use an effective barrier method (latex or polyurethane condoms/dental dams) during all sexual activity. Consult your doctor or pharmacist for more details.

Tell your doctor if you are pregnant before using this medication. Discuss the risks and benefits with your doctor.

It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding. Avoid breastfeeding if you have herpes sores on or near your breast.


Zovirax Ointment Patient Information Including Side Effects

Brand Names: Zovirax Topical

Generic Name: acyclovir topical (Pronunciation: a SY klo veer)

  • What is acyclovir topical (Zovirax Ointment)?
  • What are the possible side effects of acyclovir topical (Zovirax Ointment)?
  • What is the most important information I should know about acyclovir topical (Zovirax Ointment)?
  • What should I discuss with my healthcare provider before using acyclovir topical (Zovirax Ointment)?
  • How should I use acyclovir topical (Zovirax Ointment)?
  • What happens if I miss a dose (Zovirax Ointment)?
  • What happens if I overdose (Zovirax Ointment)?
  • What should I avoid while using acyclovir topical (Zovirax Ointment)?
  • What other drugs will affect acyclovir topical (Zovirax Ointment)?
  • Where can I get more information?

What is acyclovir topical (Zovirax Ointment)?

Acyclovir is an antiviral drug. It slows the growth and spread of the herpes virus so that the body can fight off the infection. Acyclovir will not cure herpes, but it can lessen the symptoms of the infection.

Acyclovir topical is used to treat cold sores and genital herpes.

Acyclovir topical may also be used for purposes other than those listed in this medication guide.

What are the possible side effects of acyclovir topical (Zovirax Ointment)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Less serious side effects are more likely to occur, such as itching, swelling, or pain where the medicine is applied.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about acyclovir topical (Zovirax Ointment)?

Use this medication for the entire length of time prescribed by your doctor. Your symptoms may get better before the infection is completely treated.

Treatment with acyclovir topical should be started as soon as possible after the first appearance of symptoms (such as tingling, burning, blisters).

Wear a glove or a finger cot or use a cotton swab when applying acyclovir topical to avoid spreading the virus to other body parts and to other people.

Avoid getting this medication in your eyes.

Herpes infections are contagious and you can infect other people, even while you are being treated with acyclovir topical. Avoid letting infected areas come into contact with other people. Avoid touching an infected area and then touching your eyes. Wash your hands frequently to prevent passing the infection to others.

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