Analpram HC

DRUG DESCRIPTION

Analpram HC® Cream 2.5% is a topical preparation containing hydrocortisone acetate 2.5% w/w and pramoxine hydrochloride 1% w/w in a hydrophilic cream base containing stearic acid, cetyl alcohol, Aquaphor®, isopropyl palmitate, polyoxyl 40 stearate, propylene glycol, potassium sorbate, sorbic acid, triethanolamine lauryl sulfate, and purified water.

Topical corticosteroids are anti-inflammatory and anti-pruritic agents. The structural formula, the chemical name, molecular formula and molecular weight for active ingredients are presented below.

Hydrocortisone acetate Structural Formula Illustration

hydrocortisone acetate Pregn-4-ene-3,20-dione, 21-(acetyloxy)-11, 17-dihydroxy-, (11-beta)- C23H32O6; mol, wt, 404.50

premoxine hydrochloride 4-(3-(p-butoxyphenoxy)propyl) morpholine hydrochloride C17H27NO3•HCl; mol. Wt:329.87



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