Acanya Gel

DRUG DESCRIPTION

ACANYA Gel (clindamycin phosphate 1.2% and benzoyl peroxide 2.5%) is a combination product with two active ingredients in an aqueous gel formulation. Clindamycin phosphate is a water-soluble ester of the semi-synthetic antibiotic produced by a 7(S)-chloro-substitution of the 7(R)-hydroxyl group of the parent antibiotic lincomycin.

The chemical name for clindamycin phosphate is Methyl 7-chloro?­6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1?­thio-L-threo-?-D-galacto-octopyranoside 2-(dihydrogen phosphate). The structural formula for clindamycin phosphate is represented below:

Clindamycin phosphate:

Clindamycin phosphate Structural Formula Illustration

Molecular Formula: C18H34ClN2O8PS Molecular Weight: 504.97

Benzoyl peroxide is an antibacterial and keratolytic agent. The structural formula for benzoyl peroxide is represented below:

Benzoyl peroxide:

Molecular Formula: C14H10O4 Molecular Weight: 242.23

ACANYA Gel (clindamycin phosphate 1.2% and benzoyl peroxide 2.5%) contains the following inactive ingredients: purified water, carbomer 980, propylene glycol, and potassium hydroxide. Each gram of ACANYA Gel (clindamycin phosphate 1.2% and benzoyl peroxide 2.5%) contains 1.2% of clindamycin phosphate which is equivalent to 1% clindamycin.

What are the precautions when taking clindamycin phosphate 1.2% and benzoyl peroxide 2.5% (Acanya Gel)?

Before using this medication, tell your doctor or pharmacist if you are allergic to benzoyl peroxide; or to clindamycin; or to lincomycin; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: intestinal disorders (e.g., regional enteritis, ulcerative colitis, antibiotic-associated colitis, Clostridium difficile-associated diarrhea).

This medication may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear protective clothing when...

Read All Potential Precautions of Acanya Gel »


Acanya Gel Consumer (continued)

SIDE EFFECTS: Dry skin, redness, burning, itching, or skin peeling may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

You can use skin moisturizing creams or lotions to help reduce many of the side effects listed above.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

This medication may be absorbed into your bloodstream and very rarely cause a severe intestinal condition (Clostridium difficile-associated diarrhea) due to resistant bacteria. This condition may occur weeks after treatment has stopped. Do not use anti-diarrhea products or narcotic pain medications if you have the following symptoms because these products may make them worse. Tell your doctor immediately if you develop: persistent diarrhea, abdominal or stomach pain/cramping, blood/mucus in your stool.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS: Before using this medication, tell your doctor or pharmacist if you are allergic to benzoyl peroxide; or to clindamycin; or to lincomycin; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: intestinal disorders (e.g., regional enteritis, ulcerative colitis, antibiotic-associated colitis, Clostridium difficile-associated diarrhea).

This medication may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear protective clothing when outdoors.

This medication may bleach hair or colored fabric. Avoid contact with hair or clothing.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

This drug may pass into breast milk and could have undesirable effects on a nursing infant. Consult your doctor before breast-feeding.



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