Sectral

DRUG DESCRIPTION

Sectral (acebutolol HCl) is a selective, hydrophilic beta-adrenoreceptor blocking agent with mild intrinsic sympathomimetic activity for use in treating patients with hypertension and ventricular arrhythmias. It is marketed in capsule form for oral administration. Sectral (acebutolol) capsules are provided in two dosage strengths which contain 200 or 400 mg of acebutolol as the hydrochloride salt. The inactive ingredients present are D&C Red 22, FD&C Blue 1, FD&C Yellow 6, gelatin, povidone, starch, stearic acid, and titanium dioxide. The 200 mg dosage strength also contains D&C Red 28 and the 400 mg dosage strength also contains FD&C Red 40. Acebutolol HCl has the following structural formula:

Sectral (acebutolol HCl) structural formula illustration

Acebutolol HCl is a white or slightly off-white powder freely soluble in water, and less soluble in alcohol. Chemically it is defined as the hydrochloride salt of ()N-[3-Acetyl-4-[2- hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl] butanamide.

What are the possible side effects of acebutolol (Sectral)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • slow or uneven heartbeats;
  • feeling light-headed, fainting;
  • feeling short of breath, even with mild exertion;
  • swelling of your ankles or feet;
  • nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the...

Read All Potential Side Effects and See Pictures of Sectral

What are the precautions when taking acebutolol (Sectral)?

Before taking acebutolol, tell your doctor or pharmacist if you are allergic to it; or to other beta-blockers (e.g., propranolol); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: very slow heartbeat (e.g., severe bradycardia, second- or third-degree atrioventricular block), a certain serious heart problem (cardiogenic shock), uncontrolled severe heart failure.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: blood circulation problems (e.g.,...

Read All Potential Precautions of Sectral


Sectral Consumer (continued)

SIDE EFFECTS: Dizziness, lightheadedness, drowsiness, tiredness, constipation, diarrhea, stomach upset/gas, nausea, trouble sleeping or unusual dreams may occur as your body adjusts to the medication. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

This drug may reduce blood flow to your hands and feet, causing them to feel cold. Smoking may worsen this effect. Avoid tobacco use and dress warmly.

Tell your doctor immediately if any of these unlikely but serious side effects occur: bluish discoloration of the fingers/toes/nails, severe tiredness, mental/mood changes (e.g., depression, confusion, memory problems), numbness/tingling, decreased sexual ability, trouble breathing, swelling of the feet/ankles, vision changes, unexplained/sudden weight gain.

Seek immediate medical attention if any of these unlikely but very serious side effects occur: chest pain, persistent dizziness/fainting, slow/fast/irregular heartbeat, jaw/left arm pain, black stools, rectal bleeding, severe stomach/abdominal pain.

Tell your doctor immediately if any of these rare but very serious side effects occur: easy bleeding/bruising, persistent joint/muscle pain, painful erections.

Tell your doctor immediately if you develop symptoms of liver disease, including persistent nausea, stomach/abdominal pain, dark urine, yellowing eyes/skin.

A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS: Before taking acebutolol, tell your doctor or pharmacist if you are allergic to it; or to other beta-blockers (e.g., propranolol); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: very slow heartbeat (e.g., severe bradycardia, second- or third-degree atrioventricular block), a certain serious heart problem (cardiogenic shock), uncontrolled severe heart failure.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: blood circulation problems (e.g., Raynaud's disease, peripheral vascular disease), breathing problems (e.g., asthma, chronic obstructive pulmonary disease), decreased blood flow to the heart or brain (e.g., coronary artery disease, stroke, transient ischemic attacks), diabetes, heart problems (e.g., history of heart failure, recent heart attack, valve problems), kidney problems, liver problems, mental/mood disorders (e.g., depression), certain muscle problems (myasthenia gravis), overactive thyroid disease (hyperthyroidism).

This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.

To minimize dizziness and lightheadedness, get up slowly when rising from a seated or lying position.

Before having surgery, tell your doctor or dentist that you are taking this medication.

This drug may infrequently make your blood sugar level rise, causing or worsening diabetes. Tell your doctor immediately if you develop symptoms of high blood sugar such as increased thirst or urination.

If you already have diabetes, be sure to check your blood sugar regularly. This medication may mask the fast/pounding heartbeat, nervousness and shakiness you would usually feel when your blood sugar level falls too low (hypoglycemia). Other symptoms of low blood sugar, such as hunger, dizziness and sweating, are unaffected by this drug.

If you have chest pain (angina) or have heart disease (e.g., coronary artery disease, ischemic heart disease, high blood pressure), do not stop using this drug without first consulting your doctor. Your condition may become worse when the drug is suddenly stopped. If your doctor decides you should no longer use this drug, you must gradually decrease your dose according to your doctor's instructions.

Seek immediate medical attention if you develop: worsening chest pain, tightness or pressure in the chest, chest pain spreading to the jaw/neck/arm, sweating, trouble breathing, fast/irregular heartbeat.

Caution is advised when using this drug in the elderly because they may be more sensitive to side effects.

This medication should be used only when clearly needed during pregnancy. Newborns whose mothers have taken this drug near the date of delivery may have problems such as low blood pressure, low heart rate and low birth weight, and may require special medical monitoring. Discuss the risks and benefits of taking this medication during pregnancy with your doctor.

This drug passes into breast milk. Consult your doctor before breast-feeding.


Sectral Patient Information Including Side Effects

Brand Names: Sectral

Generic Name: acebutolol (Pronunciation: A se BUE toe lol)

  • What is acebutolol (Sectral)?
  • What are the possible side effects of acebutolol (Sectral)?
  • What is the most important information I should know about acebutolol (Sectral)?
  • What should I discuss with my healthcare provider before taking acebutolol (Sectral)?
  • How should I take acebutolol (Sectral)?
  • What happens if I miss a dose (Sectral)?
  • What happens if I overdose (Sectral)?
  • What should I avoid while taking acebutolol (Sectral)?
  • What other drugs will affect acebutolol (Sectral)?
  • Where can I get more information?

What is acebutolol (Sectral)?

Acebutolol is in a group of drugs called beta-blockers. Beta-blockers affect the heart and circulation (blood flow through arteries and veins).

Acebutolol is used to treat hypertension (high blood pressure) and heart rhythm disorders.

Acebutolol may also be used for other purposes not listed in this medication guide.

What are the possible side effects of acebutolol (Sectral)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • slow or uneven heartbeats;
  • feeling light-headed, fainting;
  • feeling short of breath, even with mild exertion;
  • swelling of your ankles or feet;
  • nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
  • depression; or
  • cold feeling in your hands and feet.

Less serious side effects may include:

  • decreased sex drive, impotence, or difficulty having an orgasm;
  • sleep problems (insomnia);
  • tired feeling; or
  • anxiety, nervousness.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about acebutolol (Sectral)?

Do not stop taking acebutolol without first talking to your doctor. Stopping suddenly may make your condition worse.

If you need to have any type of surgery, you may need to temporarily stop using acebutolol. Be sure the surgeon knows ahead of time that you are using acebutolol.

Acebutolol can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid drinking alcohol, which could increase drowsiness and dizziness while you are taking acebutolol.

Acebutolol is only part of a complete program of treatment for hypertension that may also include diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely if you are being treated for hypertension.

Keep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.

Related Drug Centers
  • Sectral


Related Drugs Index: