Drugs Index
List of RX Drugs
RX Drugs Information:
DRUG DESCRIPTION
AdreView (iobenguane I 123 Injection) is a sterile, pyrogen-free radiopharmaceutical for intravenous injection. Each mL contains 0.08 mg iobenguane sulfate, 74 MBq (2 mCi) of I 123 (as iobenguane sulfate I 123) at calibration date and time on the label, 23 mg sodium dihydrogen phosphate dihydrate, 2.8 mg disodium hydrogen phosphate dihydrate and 10.3 mg (1% v/v) benzyl alcohol with a pH of 5.0 – 6.5. Iobenguane sulfate I 123 is also known as I 123 meta-iodobenzlyguanidine sulfate and has the following structural formula:
 |
Physical Characteristics
Iodine 123 is a cyclotron-produced radionuclide that decays to Te 123 by electron capture and has a physical half-life of 13.2 hours.
Table 3: Principal Radiation Emission Data – Iodine 123
| Radiation | Energy Level (keV) | Abundance (%) |
| Gamma | 159 | 83 |
External Radiation
The specific gamma ray constant for iodine 123 is 1.6 R/mCi-hr at 1 cm. The first half value thickness of lead (Pb) for I 123 is 0.04 cm. The relative transmission of radiation emitted by the radionuclide that results from interposition of various thicknesses of Pb is shown in Table 4 (e.g., the use of 2.16 cm Pb will decrease the external radiation exposure by a factor of about 1,000).
Table 4: Reduction in In-air Collision Kerma Caused by Lead
Shielding*
| Shield Thickness cm of lead (Pb) | Reduction in In-air Collision Kerma |
| 0.04 | 0.5 |
| 0.13 | 10-1 |
| 0.77 | 10-2 |
| 2.16 | 10-3 |
| 3.67 | 10-4 |
| *Calculation based on attenuation and energy-transfer coefficients obtained from National Institute of Standards & Technology Report NISTIR 5632 | |
What are the possible side effects of iobenguane I-123 (AdreView)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Less serious side effects may include:
- dizziness;
- mild skin rash or itching;
- bleeding around your IV needle; or
- warmth, tingling, or cold feeling where the medicine was injected.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may...
Read All Potential Side Effects and See Pictures of AdreView »
AdreView Patient Information Including Side Effects
Brand Names: AdreView
Generic Name: iobenguane I-123 (Pronunciation: EYE oh BEN gwayne)
- What is iobenguane I-123 (AdreView)?
- What are the possible side effects of iobenguane I-123 (AdreView)?
- What is the most important information I should know about iobenguane I-123 (AdreView)?
- What should I discuss with my health care provider before receiving iobenguane I-123 (AdreView)?
- How is iobenguane I-123 used (AdreView)?
- What happens if I miss a dose (AdreView)?
- What happens if I overdose (AdreView)?
- What should I avoid while receiving iobenguane I-123 (AdreView)?
- What other drugs will affect iobenguane I-123 (AdreView)?
- Where can I get more information?
What is iobenguane I-123 (AdreView)?
Iobenguane I-123 is in a group of drugs called diagnostic radiopharmaceuticals.(RAY dee oh far ma SOO tik als). Iobenguane I-123 is a radioactive agent that alows images of specific organs in the body to be detected by a gamma camera.
Iobenguane I-123 is used to detect certain kinds of cancer of the adrenal glands
Iobenguane I-123 may also be used for purposes other than those listed in this medication guide.
What are the possible side effects of iobenguane I-123 (AdreView)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Less serious side effects may include:
- dizziness;
- mild skin rash or itching;
- bleeding around your IV needle; or
- warmth, tingling, or cold feeling where the medicine was injected.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about iobenguane I-123 (AdreView)?
You should not receive this medication if you are allergic to iobenguane. Tell your doctor if you have ever had any type of reaction to another contrast agent, or to potassium .
Before you are treated with iobenguane I-123, tell your doctor if you have kidney disease, a thyroid disorder, if you are dehydrated or unable to urinate, or if you are allergic to iodine.
Tell your doctor about all other medications you are using, especially antidepressants, cold medicines, blood pressure medications, or ADHD medications. You may need to stop using certain drugs for a short time before you receive iobenguane I-123
Drink extra fluids before you receive iobenguane I-123, and for at least 48 hours afterward. Follow your doctor's instructions about the types and amount of liquids you should drink before and after your test. Iobenguane I-123 is radioactive and it can cause dangerous effects on your bladder if it is not properly eliminated from your body through urination.
Do not allow yourself to become dehydrated during the first few days after receiving iobenguane I-123. Call your doctor if you have any vomiting or diarrhea during this time. Follow your doctor's instructions about the types and amount of fluids you should drink.
- AdreView
Related Drugs Index:
AdreView, Iobenguane, 123, Injection, for, Intravenous, Use, Buy AdreView