Coly-Mycin M

DRUG DESCRIPTION

Coly-Mycin® M Parenteral (Colistimethate for Injection, USP) is a sterile parenteral antibiotic product which, when reconstituted (see Reconstitution), is suitable for intramuscular or intravenous administration.

Each vial contains colistimethate sodium or pentasodium colistinmethanesulfonate (150 mg colistin base activity).

Colistimethate sodium is a polypeptide antibiotic with an approximate molecular weight of 1750. The empirical formula is C58H105N16Na5O28S5 and the structural formula is represented below:

Coly-Mycin® M Parenteral 
  (Colistimethate) Structural Formula Illustration

What are the possible side effects of colistimethate (Coly Mycin M)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • diarrhea that is watery or bloody;
  • fever;
  • urinating less than usual or not at all;
  • muscle weakness; or
  • trouble breathing.

Less serious side effects may include:

  • mild numbness or tingling in your hands or...

Read All Potential Side Effects and See Pictures of Coly-Mycin M »

What are the precautions when taking colistimethate injection (Coly-Mycin M)?

Consult your...

Read All Potential Precautions of Coly-Mycin M »


Coly-Mycin M Consumer (continued)

SIDE EFFECTS: Consult your pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS: Consult your pharmacist.


Coly-Mycin M Patient Information Including Side Effects

Brand Names: Coly Mycin M

Generic Name: colistimethate (Pronunciation: koe LIS ti METH ate)

  • What is colistimethate (Coly-Mycin M)?
  • What are the possible side effects of colistimethate (Coly-Mycin M)?
  • What is the most important information I should know about colistimethate (Coly-Mycin M)?
  • What should I discuss with my health care provider before taking colistimethate (Coly-Mycin M)?
  • How should I take colistimethate (Coly-Mycin M)?
  • What happens if I miss a dose (Coly-Mycin M)?
  • What happens if I overdose (Coly-Mycin M)?
  • What should I avoid while taking colistimethate (Coly-Mycin M)?
  • What other drugs will affect colistimethate (Coly-Mycin M)?
  • Where can I get more information?

What is colistimethate (Coly-Mycin M)?

Colistimethate is an antibiotic that fights bacteria in the body.

Colistimethate is used to treat infections caused by bacteria.

Colistimethate may also be used for purposes not listed in this medication guide.

What are the possible side effects of colistimethate (Coly-Mycin M)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • diarrhea that is watery or bloody;
  • fever;
  • urinating less than usual or not at all;
  • muscle weakness; or
  • trouble breathing.

Less serious side effects may include:

  • mild numbness or tingling in your hands or feet;
  • dizziness, spinning feeling;
  • itching, mild skin rash; or
  • upset stomach.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about colistimethate (Coly-Mycin M)?

You should not use this medication if you are allergic to colistimethate.

Before using colistimethate, tell your doctor if you are allergic to any drugs, or if you have kidney disease. You may need a dose adjustment or special tests during treatment.

Colistimethate is given as an injection into a muscle or through a needle placed into a vein. Your doctor, nurse, or other healthcare provider will give you this injection. You may be shown how to inject your medicine at home. Do not self-inject this medicine if you do not fully understand how to give the injection and properly dispose of used needles and syringes.

Keep using colistimethate for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Colistimethate will not treat a viral infection such as the common cold or flu.

If you need to have any type of surgery, tell the surgeon ahead of time that you are using colistimethate. You may need to stop using the medicine for a short time.

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