Cleocin Vaginal Ovules

DRUG DESCRIPTION

Clindamycin phosphate is a water-soluble ester of the semisynthetic antibiotic produced by a 7(S)-chloro-substitution of the 7(R)-hydroxyl group of the parent antibiotic lincomycin. The chemical name for clindamycin phosphate is methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-?-D-galacto-octopyranoside 2-(dihydrogen phosphate). The monohydrate form has a molecular weight of 522.98, and the molecular formula is C18H34ClN2O8PS•H2O. The structural formula is represented below:

Cleocin® (clindamycin phosphate) Structural Formula Illustration

CLEOCIN Vaginal Ovules (clindamycin phosphate vaginal suppositories) are semisolid, white to off-white suppositories for intravaginal administration. Each 2.5 g suppository contains clindamycin phosphate equivalent to 100 mg clindamycin in a base consisting of a mixture of glycerides of saturated fatty acids.

What are the possible side effects of clindamycin vaginal (Cleocin Vaginal)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using clindamycin vaginal and call your doctor at once if you have diarrhea that is watery or bloody.

Keep using clindamycin vaginal and talk to your doctor if you have any of these less serious side effects:

  • mild nausea or stomach pain;
  • constipation, gas;
  • vaginal itching, discharge, or pain; or
  • changes in...

Read All Potential Side Effects and See Pictures of Cleocin Vaginal Ovules »


Cleocin Vaginal Ovules Patient Information Including Side Effects

Brand Names: Cleocin Vaginal

Generic Name: clindamycin vaginal (Pronunciation: klin da MYE sin)

  • What is clindamycin vaginal (Cleocin Vaginal Ovules)?
  • What are the possible side effects of clindamycin vaginal (Cleocin Vaginal Ovules)?
  • What is the most important information I should know about clindamycin vaginal (Cleocin Vaginal Ovules)?
  • What should I discuss with my healthcare provider before using clindamycin vaginal (Cleocin Vaginal Ovules)?
  • How should I use clindamycin vaginal (Cleocin Vaginal Ovules)?
  • What happens if I miss a dose (Cleocin Vaginal Ovules)?
  • What happens if I overdose (Cleocin Vaginal Ovules)?
  • What should I avoid while using clindamycin vaginal (Cleocin Vaginal Ovules)?
  • What other drugs will affect clindamycin vaginal (Cleocin Vaginal Ovules)?
  • Where can I get more information?

What is clindamycin vaginal (Cleocin Vaginal Ovules)?

Clindamycin is an antibiotic that fights bacteria in the body.

Clindamycin vaginal is used to treat vaginal infections caused by bacteria.

Clindamycin vaginal may also be used for purposes other than those listed in this medication guide.

What are the possible side effects of clindamycin vaginal (Cleocin Vaginal Ovules)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using clindamycin vaginal and call your doctor at once if you have diarrhea that is watery or bloody.

Keep using clindamycin vaginal and talk to your doctor if you have any of these less serious side effects:

  • mild nausea or stomach pain;
  • constipation, gas;
  • vaginal itching, discharge, or pain; or
  • changes in your menstrual periods; or
  • mild skin rash or itching.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about clindamycin vaginal (Cleocin Vaginal Ovules)?

Do not use this medication if you are allergic to clindamycin or lincomycin (Bactramycin, L-Mycin, Lincocin), or if you have an intestinal disorder such as colitis or Crohn's disease.

Before using clindamycin vaginal, tell your doctor if you have ever had severe diarrhea caused by using an antibiotic.

Use this medication for the entire length of time prescribed by your doctor. Your symptoms may get better before the infection is completely treated. This medication will not treat a vaginal yeast infection.

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or has blood in it, call your doctor. Do not use any medicine to stop the diarrhea unless your doctor has told you to.

If you need to have any type of surgery, tell the surgeon ahead of time that you are using clindamycin vaginal. You may need to stop using the medicine for a short time.

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