Cleocin

DRUG DESCRIPTION

Clindamycin hydrochloride is the hydrated hydrochloride salt of clindamycin. Clindamycin is a semisynthetic antibiotic produced by a 7(S)-chloro-substitution of the 7(R)-hydroxyl group of the parent compound lincomycin.

CLEOCIN HCl Capsules contain clindamycin hydrochloride equivalent to 75 mg, 150 mg or 300 mg of clindamycin.

Inactive ingredients: 75 mg-corn starch, FD&C blue no. 1, FD&C yellow no. 5, gelatin, lactose, magnesium stearate and talc; 150 mg-corn starch, FD&C blue no. 1, FD&C yellow no. 5, gelatin, lactose, magnesium stearate, talc and titanium dioxide; 300 mg-corn starch, FD&C blue no. 1, gelatin, lactose, magnesium stearate, talc and titanium dioxide.

The structural formula is represented below:

Clindamycin hydrochloride structural formula illustration

The chemical name for clindamycin hydrochloride is Methyl 7-chloro-6,7,8-trideoxy-6-(1methyl- trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-?-D-galacto-octopyranosidemonohydrochloride.

What are the possible side effects of clindamycin (Cleocin HCl, Cleocin Pediatric)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using clindamycin and call your doctor at once if you have any of these serious side effects:

  • diarrhea that is watery or bloody;
  • fever, chills, body aches, flu symptoms;
  • nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
  • urinating...

Read All Potential Side Effects and See Pictures of Cleocin

What are the precautions when taking clindamycin (Cleocin)?

Before taking clindamycin, tell your doctor or pharmacist if you are allergic to it; or to lincomycin; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have a certain medical condition. Before using this medicine, consult your doctor or pharmacist if you have: a certain intestinal condition (Clostridium difficile-associated diarrhea).

Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, kidney disease, other stomach/intestinal diseases (e.g., colitis), allergic conditions (e.g., asthma, hay fever, eczema).

Before having surgery, tell your...

Read All Potential Precautions of Cleocin


Cleocin Consumer (continued)

SIDE EFFECTS: See also Warning section.

Nausea, vomiting, or diarrhea may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately if this unlikely but serious side effect occurs: heartburn.

Tell your doctor immediately if any of these rare but very serious side effects occur: joint pain/swelling, yellowing eyes/skin, dark urine, change in the amount of urine.

Use of this medication for prolonged or repeated periods may result in oral thrush or a new vaginal yeast infection. Contact your doctor if you notice white patches in your mouth, a change in vaginal discharge, or other new symptoms.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS: Before taking clindamycin, tell your doctor or pharmacist if you are allergic to it; or to lincomycin; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have a certain medical condition. Before using this medicine, consult your doctor or pharmacist if you have: a certain intestinal condition (Clostridium difficile-associated diarrhea).

Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, kidney disease, other stomach/intestinal diseases (e.g., colitis), allergic conditions (e.g., asthma, hay fever, eczema).

Before having surgery, tell your doctor or dentist that you are using this medication (unless your doctor/dentist has directed you to take this drug before surgery as a precaution).

Older adults may be more sensitive to the effects of this drug, especially persistent diarrhea.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

This medication passes into breast milk. Though there have been no reports of harm to nursing infants, consult your doctor before breast-feeding.


Cleocin Patient Information Including Side Effects

Brand Names: Cleocin HCl, Cleocin Pediatric

Generic Name: clindamycin (Pronunciation: klin da MYE sin)

  • What is clindamycin (Cleocin)?
  • What are the possible side effects of clindamycin (Cleocin)?
  • What is the most important information I should know about clindamycin (Cleocin)?
  • What should I discuss with my healthcare provider before taking clindamycin (Cleocin)?
  • How should I take clindamycin (Cleocin)?
  • What happens if I miss a dose (Cleocin)?
  • What happens if I overdose (Cleocin)?
  • What should I avoid while taking clindamycin (Cleocin)?
  • What other drugs will affect clindamycin (Cleocin)?
  • Where can I get more information?

What is clindamycin (Cleocin)?

Clindamycin is an antibiotic that fights bacteria in the body.

Clindamycin is used to treat serious infections caused by bacteria.

Clindamycin may also be used for purposes other than those listed in this medication guide.

What are the possible side effects of clindamycin (Cleocin)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using clindamycin and call your doctor at once if you have any of these serious side effects:

  • diarrhea that is watery or bloody;
  • fever, chills, body aches, flu symptoms;
  • nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
  • urinating less than usual or not at all; or
  • fever, sore throat, and headache with a severe blistering, peeling, and red skin rash.

Keep taking clindamycin and talk to your doctor if you have any of these less serious side effects:

  • mild nausea or stomach pain;
  • vaginal itching or discharge;
  • mild skin rash or itching; or
  • irritation in your throat.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about clindamycin (Cleocin)?

Do not use this medication if you are allergic to clindamycin or lincomycin (Bactramycin, L-Mycin, Lincocin)

Do not take clindamycin together with erythromycin (E-Mycin, E.E.S., Eryc, Ery-Tab, Robimycin, and others).

Before using clindamycin, tell your doctor if you have kidney disease, liver disease, an intestinal disorder such as colitis or Crohn's disease, or a history of asthma, eczema, or allergic skin reaction.

Take this medication for the entire length of time prescribed by your doctor. Your symptoms may get better before the infection is completely treated. Clindamycin will not treat a viral infection such as the common cold or flu.

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or has blood in it, call your doctor. Do not use any medicine to stop the diarrhea unless your doctor has told you to.

To be sure this medication is not causing harmful effects, your blood will need to be tested on a regular basis. Your kidney or liver function may also need to be tested. Do not miss any scheduled visits to your doctor.

If you need to have any type of surgery, tell the surgeon ahead of time that you are using clindamycin. You may need to stop using the medicine for a short time.

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