Chibroxin

(Generic versions may still be available.)

DRUG DESCRIPTION

CHIBROXIN® (Merck)
(norfloxacin ophthalmic solution)
Sterile Ophthalmic Solution

CHIBROXIN* (norfloxacin ophthalmic solution) is a synthetic broad-spectrum antibacterial agent supplied as a sterile isotonic solution for topical ophthalmic use. Norfloxacin, a fluoroquinolone, is 1-ethyl-6-fluoro-1, 4-dihydro-4-oxo-7-(1-piperazinyl) -3- quinoline-carboxylic acid. Its empirical formula is C 16 H 18 FN 3 O 3 and the structural formula is:

norfloxacinop.htm

Norfloxacin is a white to pale yellow crystalline powder with a molecular weight of 319.34 and a melting point of about 221°C. It is freely soluble in glacial acetic acid and very slightly soluble in ethanol, methanol and water.

CHIBROXIN (norfloxacin) Ophthalmic Solution 0.3% is supplied as a sterile isotonic solution. Each mL contains 3 mg norfloxacin. Inactive ingredients: disodium edetate, sodium acetate, sodium chloride, hydrochloric acid (to adjust pH) and water for injection, Benzalkonium chloride 0.0025% is added as preservative. The pH of CHIBROXIN (norfloxacin) is approximately 5.2 and the osmolarity is approximately 285 m0smol/liter.

Norfloxacin, a fluoroquinolone, differs from quinolones by having a fluorine atom at the 6 position and a piperazine moiety at the 7 position.


*Registered trademark of MERCK & CO., INC.

What are the possible side effects of norfloxacin ophthalmic (Chibroxin)?

Serious side effects are not expected with this medication.

If you are using norfloxacin ophthalmic to treat a corneal ulcer, you may notice a whitish buildup on the ulcer. This means that the medication is working; it is not a harmful development.

Commonly, some eye burning, stinging, irritation, itching, redness, blurred vision, eyelid itching, eyelid swelling or crusting, a bad taste in your mouth, tearing, or sensitivity to light may occur.

This is not a complete list of side effects and others may occur. Call...

Read All Potential Side Effects and See Pictures of Chibroxin »


Chibroxin Patient Information Including Side Effects

Brand Names: Chibroxin

Generic Name: norfloxacin ophthalmic (Pronunciation: nor FLOX a sin off THAL mik)

  • What is norfloxacin ophthalmic (Chibroxin)?
  • What are the possible side effects of norfloxacin ophthalmic (Chibroxin)?
  • What is the most important information I should know about norfloxacin ophthalmic (Chibroxin)?
  • Who should not use norfloxacin ophthalmic (Chibroxin)?
  • How should I use norfloxacin ophthalmic (Chibroxin)?
  • What happens if I miss a dose (Chibroxin)?
  • What happens if I overdose (Chibroxin)?
  • What should I avoid while using norfloxacin ophthalmic (Chibroxin)?
  • What other drugs will affect norfloxacin ophthalmic (Chibroxin)?
  • Where can I get more information?

What is norfloxacin ophthalmic (Chibroxin)?

Norfloxacin ophthalmic is an antibiotic.

Norfloxacin ophthalmic is used to treat bacterial infections of the eyes.

Norfloxacin ophthalmic may also be used for purposes other than those listed in this medication guide.

What are the possible side effects of norfloxacin ophthalmic (Chibroxin)?

Serious side effects are not expected with this medication.

If you are using norfloxacin ophthalmic to treat a corneal ulcer, you may notice a whitish buildup on the ulcer. This means that the medication is working; it is not a harmful development.

Commonly, some eye burning, stinging, irritation, itching, redness, blurred vision, eyelid itching, eyelid swelling or crusting, a bad taste in your mouth, tearing, or sensitivity to light may occur.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about norfloxacin ophthalmic (Chibroxin)?

Do not touch the dropper to any surface, including your eyes or hands. The dropper is sterile. If it becomes contaminated, it could cause an infection in your eye.

Apply light pressure to the inside corner of your eye (near your nose) after each drop to prevent the fluid from draining down your tear ducts.

If you wear contact lenses, ask your doctor if you should wear them during treatment. Norfloxacin ophthalmic can cause the development of crystals on contact lenses. After applying this medication, wait at least 15 minutes before inserting contact lenses, unless otherwise directed by your doctor.

Related Drug Centers
  • Chibroxin


Related Drugs Index: