Carbocaine

DRUG DESCRIPTION

Mepivacaine hydrochloride is 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-methyl, monohydrochloride and has the following structural formula:

Carbocaine™ (Mepivacaine Hydrochloride) Structural Formula Illustration

C15H22N2O HCI

It is a white crystalline odorless powder, soluble in water, but very resistant to both acid and alkaline hydrolysis.

CARBOCAINE (mepivacaine) is a local anesthetic available as sterile isotonic solutions (clear, colorless) in concentrations of 1%, 1.5%, and 2% for injection via local infiltration, peripheral nerve block, and caudal and lumbar epidural blocks.

Mepivacaine hydrochloride is related chemically and pharmacologically to the amide-type local anesthetics. It contains an amide linkage between the aromatic nucleus and the amino group.

Composition of Available Solutions*

  1% Single-
Dose 30 mL Vial
mg/mL
1% Multiple-
Dose 50 mL Vial
mg/mL
1.5% Single-
Dose 30 mL Vial
mg/mL
2% Single-
Dose 20 mL Vial
mg/mL
2% Multiple-
Dose 50 mL
Vial mg/mL
Mepivacaine hydrochloride 10 10 15 20 20
Sodium chloride 6.6 7 5.6 4.6 5
Potassium chloride 0.3   0.3 0.3  
Calcium chloride 0.33   0.33 0.33  
Methylparaben   1     1
*In Water for Injection.

The pH of the solution is adjusted between 4.5 and 6.8 with sodium hydroxide or hydrochloric acid.

What are the possible side effects of mepivacaine (Carbocaine, Carbocaine HCl, Polocaine, Polocaine-MPF)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling or puffiness of your face, lips, tongue, or throat.

Tell your caregivers at once if you have a serious side effect such as:

  • weak or shallow breathing;
  • feeling like you might pass out;
  • sweating, anxiety, confusion;
  • blurred vision, ringing in your ears;
  • numbness or tingling around your mouth;
  • slow heart...

Read All Potential Side Effects and See Pictures of Carbocaine »


Carbocaine Patient Information Including Side Effects

Brand Names: Carbocaine, Carbocaine HCl, Polocaine, Polocaine-MPF

Generic Name: mepivacaine (Pronunciation: me PIV a kane)

  • What is mepivacaine (Carbocaine)?
  • What are the possible side effects of mepivacaine (Carbocaine)?
  • What is the most important information I should know about mepivacaine (Carbocaine)?
  • What should I discuss with my health care provider before receiving mepivacaine (Carbocaine)?
  • How is mepivacaine given (Carbocaine)?
  • What happens if I miss a dose (Carbocaine)?
  • What happens if I overdose (Carbocaine)?
  • What should I avoid after receiving mepivacaine (Carbocaine)?
  • What other drugs will affect mepivacaine (Carbocaine)?
  • Where can I get more information?

What is mepivacaine (Carbocaine)?

Mepivacaine is an anesthetic (numbing medicine) that blocks the nerve impulses that send pain signals to your brain.

Mepivacaine is used as a local (in only one area) anesthetic for an epidural or spinal block. It is also used as an anesthetic for dental procedures.

Mepivacaine may also be used for other purposes not listed in this medication guide.

What are the possible side effects of mepivacaine (Carbocaine)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling or puffiness of your face, lips, tongue, or throat.

Tell your caregivers at once if you have a serious side effect such as:

  • weak or shallow breathing;
  • feeling like you might pass out;
  • sweating, anxiety, confusion;
  • blurred vision, ringing in your ears;
  • numbness or tingling around your mouth;
  • slow heart rate, weak pulse;
  • metallic taste in your mouth;
  • tremors, muscle twitching; or
  • seizure (convulsions).

Less serious side effects may include:

  • nausea, vomiting;
  • nervousness;
  • dizziness; or
  • drowsiness.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about mepivacaine (Carbocaine)?

You should not receive mepivacaine if you have ever had an allergic reaction to any type of numbing medicine.

Before receiving this medication, tell your doctor if you have liver disease, kidney disease, high or low blood pressure, asthma or a sulfite allergy, a history of heart disease or stroke, heart block or coronary artery disease, a heart rhythm disorder, or a thyroid disorder.

This medication can cause numbness for an extended period of time. Avoid eating, chewing gum, or drinking hot liquids until the feeling in your mouth has returned completely. Chewing while your mouth is numb could result in a bite injury to your tongue, lips, or inside of your cheek.

Spinal numbing medications can have long-lasting or permanent effects on certain body processes such as sexual function, bowel or bladder control, and movement or feeling in your legs or feet. Talk with your doctor about your specific risk of nerve damage from mepivacaine.

Related Drug Centers
  • Carbocaine


Related Drugs Index: