Capastat Sulfate

DRUG DESCRIPTION

Capastat Sulfate (capreomycin for injection) is a polypeptide antibiotic isolated from Streptomyces capreolus. It is a complex of 4 microbiologically active components which have been characterized in part; however, complete structural determination of all the components has not been established.

Capreomycin is supplied as the disulfate salt and is soluble in water. In complete solution, it is almost colorless.

Each vial contains the equivalent of 1 g capreomycin activity.

The structural formula is as follows:

Capastat Sulfate Structural Formula Illustration

What are the possible side effects of capreomycin (Capastat Sulfate)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using capreomycin and call your doctor at once if you have any of these serious side effects:

  • urinating less than usual or not at all;
  • changes in your hearing;
  • spinning sensation, problems with balance;
  • ringing or roaring sound in your ears; or
  • low potassium (confusion, uneven heart rate, extreme thirst,...

Read All Potential Side Effects and See Pictures of Capastat Sulfate

What are the precautions when taking capreomycin for injection (Capastat Sulfate)?

Before using capreomycin, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, hearing trouble, dehydration, liver disease, a certain muscle disease (myasthenia gravis), Parkinson's disease.

This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.

Kidney function declines as you grow older. This medication is removed by the kidneys. Therefore,...

Read All Potential Precautions of Capastat Sulfate


Capastat Sulfate Consumer (continued)

SIDE EFFECTS: Pain, irritation, or skin hardening at the injection site may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately if any of these unlikely but serious side effects occur: change in the amount of urine, ringing in the ears, trouble hearing, dizziness.

Tell your doctor immediately if any of these rare but very serious side effects occur: muscle weakness/cramps, irregular heartbeat, easy bleeding/bruising.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS: Before using capreomycin, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, hearing trouble, dehydration, liver disease, a certain muscle disease (myasthenia gravis), Parkinson's disease.

This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.

Kidney function declines as you grow older. This medication is removed by the kidneys. Therefore, elderly people may be at a greater risk for side effects while using this drug.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.


Capastat Sulfate Patient Information Including Side Effects

Brand Names: Capastat Sulfate

Generic Name: capreomycin (Pronunciation: KAP ree oh MYE sin)

  • What is capreomycin (Capastat Sulfate)?
  • What are the possible side effects of capreomycin (Capastat Sulfate)?
  • What is the most important information I should know about capreomycin (Capastat Sulfate)?
  • What should I discuss with my health care provider before using capreomycin (Capastat Sulfate)?
  • How is capreomycin given (Capastat Sulfate)?
  • What happens if I miss a dose (Capastat Sulfate)?
  • What happens if I overdose (Capastat Sulfate)?
  • What should I avoid while using capreomycin (Capastat Sulfate)?
  • What other drugs will affect capreomycin (Capastat Sulfate)?
  • Where can I get more information?

What is capreomycin (Capastat Sulfate)?

Capreomycin is an antibiotic that fights bacteria in the body.

Capreomycin is used to treat Mycobacterium tuberculosis.

Capreomycin is usually given after other tuberculosis medications have been tried without successful treatment of the infection.

Capreomycin may also be used for other purposes not listed in this medication guide.

What are the possible side effects of capreomycin (Capastat Sulfate)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using capreomycin and call your doctor at once if you have any of these serious side effects:

  • urinating less than usual or not at all;
  • changes in your hearing;
  • spinning sensation, problems with balance;
  • ringing or roaring sound in your ears; or
  • low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling).

Less serious side effects may include:

  • mild skin rash;
  • fever, chills, body aches, flu symptoms; or
  • pain, swelling, or a hard lump where the injection was given.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about capreomycin (Capastat Sulfate)?

You should not use this medication if you are allergic to capreomycin.

Before using capreomycin, tell your doctor if you are allergic to any drugs, or if you have kidney disease or hearing impairment.

To be sure this medication is not causing harmful effects, your kidney function will need to be tested on a regular basis. Your hearing may also need to be checked. Do not miss any scheduled appointments.

Use this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Capreomycin will not treat a viral infection such as the common cold or flu.

Stop using this medicine if you have a serious side effect such as hearing loss, ringing in your ears, spinning sensation, problems with balance, extreme thirst, leg discomfort, muscle weakness, limp feeling, or urinating less than usual or not at all.

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