Cordran Lotion

DRUG DESCRIPTION

Cordran® (flurandrenolide, USP) is a potent corticosteroid intended for topical use. Flurandrenolide occurs as white to off-white, fluffy, crystalline powder and is odorless. Flurandrenolide is practically insoluble in water and in ether. One g dissolves in 72 mL of alcohol and in 10 mL of chloroform. The molecular weight of flurandrenolide is 436.52.

The chemical name of flurandrenolide is Pregn-4-ene-3,20-dione, 6-fluoro-11,21-dihydroxy-16,17-[(l-methylethylidene)bis (oxy)]-, (6?, 11?, 16?)-; its empirical formula is C24H33FO6. The structure is as follows:

Cordran®
  (flurandrenolide) Structural Formula Illustration

Each mL of Cordran Lotion contains 0.5 mg (1.145 ?mol) (0.05%) flurandrenolide in an oil-in-water emulsion base composed of glycerin, cetyl alcohol, stearic acid, glyceryl monostearate, mineral oil, polyoxyl 40 stearate, menthol, benzyl alcohol, and purified water.

What are the possible side effects of flurandrenolide topical (Cordran, Cordran SP, Cordran Tape)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have severe irritation of any treated skin, or if you show signs of absorbing flurandrenolide topical through your skin, such as:

  • blurred vision, or seeing halos around lights;
  • mood changes;
  • sleep problems (insomnia);
  • weight gain,...

Read All Potential Side Effects and See Pictures of Cordran Lotion »


Cordran Lotion Patient Information Including Side Effects

Brand Names: Cordran, Cordran SP, Cordran Tape

Generic Name: flurandrenolide topical (Pronunciation: FLUR an DREN oh lide)

  • What is flurandrenolide topical (Cordran Lotion)?
  • What are the possible side effects of flurandrenolide topical (Cordran Lotion)?
  • What is the most important information I should know about flurandrenolide topical (Cordran Lotion)?
  • What should I discuss with my healthcare provider before using flurandrenolide topical (Cordran Lotion)?
  • How should I use flurandrenolide topical (Cordran Lotion)?
  • What happens if I miss a dose (Cordran Lotion)?
  • What happens if I overdose (Cordran Lotion)?
  • What should I avoid while using flurandrenolide topical (Cordran Lotion)?
  • What other drugs will affect flurandrenolide topical (Cordran Lotion)?
  • Where can I get more information?

What is flurandrenolide topical (Cordran Lotion)?

Flurandrenolide is a topical (for the skin) steroid. It reduces the actions of chemicals in the body that cause inflammation, redness, and swelling.

Flurandrenolide topical is used to treat the inflammation and itching caused by a number of skin conditions such as allergic reactions, eczema, and psoriasis.

Flurandrenolide topical may also be used for other purposes not listed in this medication guide.

What are the possible side effects of flurandrenolide topical (Cordran Lotion)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have severe irritation of any treated skin, or if you show signs of absorbing flurandrenolide topical through your skin, such as:

  • blurred vision, or seeing halos around lights;
  • mood changes;
  • sleep problems (insomnia);
  • weight gain, puffiness in your face; or
  • muscle weakness, feeling tired.

Less serious side effects may include:

  • mild skin itching, burning, or dryness;
  • thinning or softening of your skin;
  • skin rash or irritation around your mouth;
  • swollen hair follicles;
  • changes in color of treated skin;
  • blisters, pimples, or crusting of treated skin; or
  • stretch marks.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about flurandrenolide topical (Cordran Lotion)?

Use this medication exactly as directed on the label, or as it has been prescribed by your doctor. Do not use the medication in larger amounts or for longer than recommended. Topical steroid medicine can be absorbed through the skin, which may cause steroid side effects throughout the body.

Do not cover treated skin areas with a bandage or other covering unless your doctor has told you to. Plastic film covering (such as plastic wrap) is sometimes used when treating psoriasis. Follow your doctor's instructions.

If you are treating the diaper area of a baby, do not use plastic pants or tight-fitting diapers. Covering the skin that is treated with flurandrenolide topical can increase the amount of medicine your skin absorbs, which may lead to unwanted side effects.

Do not use this medication on a child without a doctor's advice. Children are more likely to absorb large amounts of a topical steroid through the skin. Steroid absorption in children may cause unwanted side effects, or a delay in growth with long-term use. Talk with your doctor if you think your child is not growing at a normal rate while using this medication over a long treatment period.

Contact your doctor if your condition does not improve, or if you develop signs of a bacterial, fungal, or viral skin infection.

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