Lodosyn

DRUG DESCRIPTION

Carbidopa, an inhibitor of aromatic amino acid decarboxylation, is a white, crystalline compound, slightly soluble in water, with a molecular weight of 244.3. It is designated chemically as ()-L-?-hydrazino-?-methyl-?-(3,4-dihydroxybenzene) propanoic acid monohydrate. Its empirical formula is C10H14N2O4H2O, and its structural formula is:

LODOSYN (Carbidopa) Structural Formula Illustration

LODOSYN (Carbidopa) tablets contain 25 mg of carbidopa. Inactive ingredients are cellulose, FD&C Yellow 6, magnesium stearate and starch.

Tablet content is expressed in terms of anhydrous carbidopa which has a molecular weight of 226.3.

What are the possible side effects of carbidopa (Lodosyn)?

Carbidopa alone is not associated with side effects. The following side effects are generally associated with carbidopa and levodopa therapy.

If you experience any of the following serious side effects, stop taking carbidopa and levodopa and seek emergency medical attention or contact your doctor immediately:

  • an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
  • uncontrolled movements of a part of the body;
  • seizures;
  • persistent...

Read All Potential Side Effects and See Pictures of Lodosyn

What are the precautions when taking carbidopa (Lodosyn)?

Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: certain eye problem (narrow-angle glaucoma).

Before using this medication, tell your doctor or pharmacist your medical history, especially of: breathing problems (e.g., asthma, emphysema), certain eye problem (wide-angle glaucoma), heart or blood vessel problems (e.g., arrhythmias, heart attack, angina), kidney disease, liver disease, mental/mood disorders (e.g.,...

Read All Potential Precautions of Lodosyn


Lodosyn Consumer (continued)

SIDE EFFECTS: Side effects with carbidopa are rare and usually occur due to the effect of levodopa or other drugs used along with this medication. Consult the Side Effects information of the levodopa-containing product(s) as well as any other drugs you are using. If you have any questions or notice any effects, consult your doctor or pharmacist.

Tell your doctor immediately if you notice worsening involuntary muscle movements/spasms, greatly increased eye blinking/twitching, or mental/mood changes (e.g., confusion, depression, hallucinations, thoughts of suicide). Your doctor may decide to lower your levodopa dose.

Dizziness, nausea, and vomiting may occur. If any of these effects persist or worsen, contact your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately if any of these unlikely but serious side effects occur: irregular heartbeat, fainting.

Tell your doctor immediately if any of these rare but very serious side effects occur: easy bleeding/bruising, signs of infection (e.g., fever, persistent sore throat), tingling of the hands/feet, vision changes (e.g., blurred/double vision).

Seek immediate medical attention if any of these rare but very serious side effects occur: chest pain, seizures, vomit that looks like coffee grounds, black/tarry stools.

Abruptly stopping or reducing the dose of this medication may rarely cause a serious (sometimes fatal) condition (neuroleptic malignant syndrome). Seek immediate medical attention if any of these rare but very serious side effects occur: fast/shallow breathing, confusion, severe dizziness/fainting, high fever, muscle stiffness, unusual sweating.

For males, in the very unlikely event you have a painful or prolonged erection (lasting more than 4 hours), stop using this drug and seek immediate medical attention or permanent problems could occur.

A very serious allergic reaction is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS: Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: certain eye problem (narrow-angle glaucoma).

Before using this medication, tell your doctor or pharmacist your medical history, especially of: breathing problems (e.g., asthma, emphysema), certain eye problem (wide-angle glaucoma), heart or blood vessel problems (e.g., arrhythmias, heart attack, angina), kidney disease, liver disease, mental/mood disorders (e.g., depression, schizophrenia), peptic ulcer, seizure.

This drug may make you dizzy or cause blurred vision. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely. Avoid alcoholic beverages.

To minimize lightheadedness, get up slowly when rising from a sitting or lying position.

Before having surgery, tell your doctor or dentist that you are taking this medication.

This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor.

It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding.


Lodosyn Patient Information Including Side Effects

Brand Names: Lodosyn

Generic Name: carbidopa (Pronunciation: kar bi DOE pa)

  • What is carbidopa (Lodosyn)?
  • What are the possible side effects of carbidopa (Lodosyn)?
  • What is the most important information I should know about carbidopa (Lodosyn)?
  • What should I discuss with my healthcare provider before taking carbidopa (Lodosyn)?
  • How should I take carbidopa (Lodosyn)?
  • What happens if I miss a dose (Lodosyn)?
  • What happens if I overdose (Lodosyn)?
  • What should I avoid while taking carbidopa (Lodosyn)?
  • What other drugs will affect carbidopa (Lodosyn)?
  • Where can I get more information?

What is carbidopa (Lodosyn)?

Carbidopa is used with levodopa to treat Parkinson's disease. Parkinson's disease is believed to be related to low levels of a chemical called dopamine (DOE pa meen) in the brain. Levodopa (Dopar, Larodopa) is turned into dopamine in the body. Carbidopa is used with levodopa to prevent the breakdown (metabolism) of levodopa before it can reach the brain and take effect. Carbidopa is only effective if it is taken with levodopa. It has no effect if it is used alone.

Carbidopa is used with levodopa to treat the stiffness, tremors, spasms, and poor muscle control of Parkinson's disease. These medications are also used to treat the same muscular conditions when they are caused by drugs such as chlorpromazine (Thorazine), fluphenazine (Prolixin), perphenazine (Trilafon), and others.

Carbidopa may also be used for purposes other than those listed in this medication guide.

What are the possible side effects of carbidopa (Lodosyn)?

Carbidopa alone is not associated with side effects. The following side effects are generally associated with carbidopa and levodopa therapy.

If you experience any of the following serious side effects, stop taking carbidopa and levodopa and seek emergency medical attention or contact your doctor immediately:

  • an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
  • uncontrolled movements of a part of the body;
  • seizures;
  • persistent nausea, vomiting, or diarrhea;
  • an irregular heartbeat or fluttering in your chest;
  • unusual changes in mood or behavior; or
  • depression or suicidal thoughts.

Other, less serious side effects may be more likely to occur. Continue to take carbidopa and levodopa and talk to your doctor if you experience

  • mild nausea, vomiting, or decreased appetite;
  • constipation, dry mouth, or blurred vision;
  • hand tremor;
  • muscle twitches;
  • dizziness or drowsiness;
  • insomnia, confusion, or nightmares;
  • agitation or anxiety;
  • darkening of urine or sweat; or
  • fatigue.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about carbidopa (Lodosyn)?

Carbidopa is only used in combination with levodopa. It has no effect if it is used on its own.

Use caution when driving, operating machinery, or performing other hazardous activities. Carbidopa may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.

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