Ciloxan Ophthalmic Solution

DRUG DESCRIPTION

CILOXAN® (ciprofloxacin HCL ophthalmic solution) is a synthetic, sterile, multiple dose, antimicrobial for topical use. Ciprofloxacin is a fluoroquinolone antibacterial active against a broad spectrum of gram positive and gram-negative ocular pathogens. It is available as the monohydrochloride monohydrate salt of 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinoline-carboxylic acid. It is a faint to light yellow crystalline powder with a molecular weight of 385.8. Its empirical formula is C17H18FN3O3??·HCl??·H2O and its chemical structure is as follows:

Ciprofloxacin differs from other quinolones in that it has a fluorine atom at the 6-position, a piperazine moiety at the 7-position, and a cyclopropyl ring at the 1-position.

Each mL of CILOXAN Ophthalmic Solution (ciprofloxacin hcl ophthalmic solution) contains: Active: ciprofloxacin HCl 3.5 mg equivalent to 3 mg base. Preservative: benzalkonium chloride 0.006%. Inactives: sodium acetate, acetic acid, mannitol 4.6%, edetate disodium 0.05%, hydrochloric acid and/or sodium hydroxide (to adjust pH) and Purified Water. The pH is approximately 4.5 and the osmolality is approximately 300 mOsm.

What are the possible side effects of ciprofloxacin ophthalmic (Ciloxan)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; slow heart rate, weak pulse, fainting; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

  • severe swelling, itching, burning, redness, or discomfort in or around your eye;
  • eye pain, vision changes, increased sensitivity of your eyes to light;
  • signs of new infection, such as drainage, crusting, or oozing of your eyes...

Read All Potential Side Effects and See Pictures of Ciloxan Ophthalmic Solution »

What are the precautions when taking ciprofloxacin hcl ophthalmic solution (Ciloxan Ophthalmic Solution)?

Before using ciprofloxacin, tell your doctor or pharmacist if you are allergic to it; or to other quinolones (e.g., levofloxacin, moxifloxacin); or if you have any other allergies. This product may contain inactive ingredients (such as preservatives like benzalkonium chloride), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: contact lens use, other eye problems.

Your vision may be temporarily blurred or unstable after applying this drug. Do not drive, use machinery, or do any activity that requires clear vision until you are sure you can perform such activities safely. Limit alcoholic beverages.

This medication should be...

Read All Potential Precautions of Ciloxan Ophthalmic Solution »


Ciloxan Ophthalmic Solution Consumer (continued)

SIDE EFFECTS: This medication may temporarily sting or burn your eyes for a minute or two when applied. Eye discomfort, itching, redness, tearing, eyelid crusting, feeling as if something is in your eye, blurred vision, a bad taste in your mouth, or sensitivity to light may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

White crystals may appear in the treated eye(s) after the first few days of ciprofloxacin use, but usually go away in a few weeks. This effect is harmless. Keep your scheduled appointments so your doctor can closely monitor your eye infection. If you notice any new or worsening eye symptoms (e.g., increased discharge, eye pain), tell your doctor immediately.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Use of this medication for prolonged or repeated periods may result in a new fungal eye infection. Do not use it for longer than prescribed. Contact your doctor if you notice new or worsening symptoms.

Tell your doctor immediately if any of these unlikely but serious side effects occur: staining of the eyes, swelling in or around the eye, eye pain, worsening vision.

A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS: Before using ciprofloxacin, tell your doctor or pharmacist if you are allergic to it; or to other quinolones (e.g., levofloxacin, moxifloxacin); or if you have any other allergies. This product may contain inactive ingredients (such as preservatives like benzalkonium chloride), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: contact lens use, other eye problems.

Your vision may be temporarily blurred or unstable after applying this drug. Do not drive, use machinery, or do any activity that requires clear vision until you are sure you can perform such activities safely. Limit alcoholic beverages.

This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor.

It is not known if the medication in this product passes into breast milk. Consult your doctor before breast-feeding.


Ciloxan Ophthalmic Solution Patient Information Including Side Effects

Brand Names: Ciloxan

Generic Name: ciprofloxacin ophthalmic (Pronunciation: SIP roe FLOX a sin off THAL mik)

  • What is ciprofloxacin ophthalmic (Ciloxan Ophthalmic Solution)?
  • What are the possible side effects of ciprofloxacin ophthalmic (Ciloxan Ophthalmic Solution)?
  • What is the most important information I should know about ciprofloxacin ophthalmic (Ciloxan Ophthalmic Solution)?
  • What should I discuss with my healthcare provider before using ciprofloxacin ophthalmic (Ciloxan Ophthalmic Solution)?
  • How should I use ciprofloxacin ophthalmic (Ciloxan Ophthalmic Solution)?
  • What happens if I miss a dose (Ciloxan Ophthalmic Solution)?
  • What happens if I overdose (Ciloxan Ophthalmic Solution)?
  • What should I avoid while using ciprofloxacin ophthalmic (Ciloxan Ophthalmic Solution)?
  • What other drugs will affect ciprofloxacin ophthalmic (Ciloxan Ophthalmic Solution)?
  • Where can I get more information?

What is ciprofloxacin ophthalmic (Ciloxan Ophthalmic Solution)?

Ciprofloxacin is an antibiotic in a group of drugs called fluoroquinolones (flor-o-KWIN-o-lones). Ciprofloxacin fights bacteria in the body.

Ciprofloxacin ophthalmic (for the eyes) is used to treat eye infections caused by bacteria. Ciprofloxacin ophthalmic is also used to treat an ulcer in the cornea of the eye.

Ciprofloxacin ophthalmic may also be used for other purposes not listed in this medication guide.

What are the possible side effects of ciprofloxacin ophthalmic (Ciloxan Ophthalmic Solution)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; slow heart rate, weak pulse, fainting; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

  • severe swelling, itching, burning, redness, or discomfort in or around your eye;
  • eye pain, vision changes, increased sensitivity of your eyes to light;
  • signs of new infection, such as drainage, crusting, or oozing of your eyes or eyelids;
  • the first sign of any skin rash, no matter how mild.

Less serious side effects may include:

  • mild itching, burning, redness, or irritation;
  • blurred vision, dry or watery eyes;
  • puffy eyelids;
  • feeling like something is in your eye;
  • a white-colored buildup in your eye (if you are being treated for corneal ulcer); or
  • nausea, unpleasant taste in your mouth after using the drops.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about ciprofloxacin ophthalmic (Ciloxan Ophthalmic Solution)?

You should not use this medication if you allergic to ciprofloxacin (Cipro) or similar medications such as levofloxacin (Levaquin), lomefloxacin (Maxaquin), moxifloxacin (Avelox), ofloxacin (Floxin), norfloxacin (Noroxin), and others.

Avoid wearing contact lenses while you still have active symptoms of the eye infection you are treating. Do not use other eye drops or medications during treatment unless otherwise directed by your doctor.

Do not allow the tip of the tube or dropper to touch any surface, including the eyes or hands. If the dropper becomes contaminated it could cause an infection in your eye, which can lead to vision loss or serious damage to the eye.

While treating a corneal ulcer, you may notice a whitish buildup in your eye. This is a sign that the medication is working and is not a harmful effect. This buildup should clear within a few days or weeks of treatment.

Ciprofloxacin ophthalmic can cause blurred vision. Be careful if you drive or do anything that requires you to be able to see clearly.

Call your doctor at once if you have a serious side effect such as severe swelling, itching, burning, redness, or discomfort, eye pain or vision changes, signs of new eye infection (drainage, crusting, or oozing), or the first sign of any skin rash, no matter how mild.

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