Catapres

DRUG DESCRIPTION

Catapres (clonidine hydrochloride, USP) is a centrally acting alpha-agonist hypotensive agent available as tablets for oral administration in three dosage strengths: 0.1 mg, 0.2 mg and 0.3 mg. The 0.1 mg tablet is equivalent to 0.087 mg of the free base.

The inactive ingredients are colloidal silicon dioxide, corn starch, dibasic calcium phosphate, FD&C Yellow No. 6, gelatin, glycerin, lactose, and magnesium stearate. The Catapres (clonidine) 0.1 mg tablet also contains FD&C Blue No.1 and FD&C Red No.3.

Clonidine hydrochloride is an imidazoline derivative and exists as a mesomeric compound. The chemical name is 2-(2,6-dichlorophenylamino)-2-imidazoline hydrochloride. The following is the structural formula:

Catapres 
(clonidine hydrochloride) Structural Formula Illustration

C9H9Cl2N3•HCl       Mol. Wt. 266.56

Clonidine hydrochloride is an odorless, bitter, white, crystalline substance soluble in water and alcohol.

What are the possible side effects of clonidine (Catapres)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • fast or pounding heartbeats;
  • a very slow heart rate (fewer than 60 beats per minute);
  • feeling short of breath, even with mild exertion;
  • swelling, rapid weight gain;
  • confusion, hallucinations;
  • fever, pale skin;
  • urinating less than...

Read All Potential Side Effects and See Pictures of Catapres »

What are the precautions when taking clonidine (Catapres)?

Before taking clonidine, tell your doctor or pharmacist if you are allergic to it; or if you have previously had a rash while using clonidine patches; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, heart disease (e.g., severe coronary artery disease, irregular heart rhythm, recent heart attack), depression, blood circulation disorders (e.g., Raynaud's disease, stroke).

Before having surgery, tell your doctor or dentist that you are taking this medication.

This drug may make you dizzy or drowsy. Do not drive, use machinery,...

Read All Potential Precautions of Catapres »


Catapres Consumer (continued)

SIDE EFFECTS: Dizziness, lightheadedness, drowsiness, dry mouth, or constipation may occur as your body adjusts to the medication. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

To relieve dry mouth, suck on (sugarless) hard candy or ice chips, chew (sugarless) gum, drink water, or use a saliva substitute.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately if any of these unlikely but serious side effects occur: fast/slow/irregular heartbeat, mental/mood changes (e.g., depression), cold hands/feet.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS: Before taking clonidine, tell your doctor or pharmacist if you are allergic to it; or if you have previously had a rash while using clonidine patches; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, heart disease (e.g., severe coronary artery disease, irregular heart rhythm, recent heart attack), depression, blood circulation disorders (e.g., Raynaud's disease, stroke).

Before having surgery, tell your doctor or dentist that you are taking this medication.

This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.

To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.

Contact lens wearers may need to use appropriate lubricating solutions if this medication causes dry eyes.

Older adults may be more sensitive to the effects of this product, especially dizziness.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

This drug passes into breast milk. Consult your doctor before breast-feeding.


Catapres Patient Information Including Side Effects

Brand Names: Catapres

Generic Name: clonidine (oral) (Pronunciation: KLOE ni deen)

  • What is clonidine (Catapres)?
  • What are the possible side effects of clonidine (Catapres)?
  • What is the most important information I should know about clonidine (Catapres)?
  • What should I discuss with my healthcare provider before taking clonidine (Catapres)?
  • How should I take clonidine (Catapres)?
  • What happens if I miss a dose (Catapres)?
  • What happens if I overdose (Catapres)?
  • What should I avoid while taking clonidine (Catapres)?
  • What other drugs will affect clonidine (Catapres)?
  • Where can I get more information?

What is clonidine (Catapres)?

Clonidine lowers blood pressure by decreasing the levels of certain chemicals in your blood. This allows your blood vessels to relax and your heart to beat more slowly and easily.

Clonidine is used to treat hypertension (high blood pressure). It is sometimes used together with other blood pressure medications.

Clonidine may also be used for other purposes not listed in this medication guide.

What are the possible side effects of clonidine (Catapres)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • fast or pounding heartbeats;
  • a very slow heart rate (fewer than 60 beats per minute);
  • feeling short of breath, even with mild exertion;
  • swelling, rapid weight gain;
  • confusion, hallucinations;
  • fever, pale skin;
  • urinating less than usual or not at all; or
  • feeling like you might pass out.

Less serious side effects may include:

  • feeling dizzy, drowsy, tired, or nervous;
  • dry mouth;
  • dry or burning eyes, blurred vision;
  • headache, muscle or joint pain;
  • nausea, vomiting, constipation, loss of appetite;
  • sleep problems (insomnia);
  • urinating more at night;
  • mild skin rash or itching; or
  • decreased sex drive, impotence.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about clonidine (Catapres)?

Before you take clonidine, tell your doctor if you have heart disease or severe coronary artery disease, a heart rhythm disorder, a history of heart attack or stroke, kidney disease, or if you have ever had an allergic reaction to a clonidine transdermal skin patch (Catapres TTS).

Do not stop taking this medication suddenly without first talking to your doctor. Stopping this medication suddenly can cause nervousness, agitation, headache, tremors, severe high blood pressure, or life-threatening symptoms. Talk with your doctor about how to avoid withdrawal symptoms when you stop taking clonidine.

Avoid drinking alcohol. It can increase some of the side effects of clonidine.

Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Clonidine can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Keep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.

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