Cholera Vaccine

DRUG DESCRIPTION

Cholera Vaccine, USP is a sterile suspension of equal parts of Ogawa and Inaba serotypes of killed Vibrio cholerae (V. comma) in buffered sodium chloride injection. The Inaba and Ogawa strains of V. cholerae are grown on trypticase soy agar medium, removed from the medium with buffered sodium chloride injection and killed by the addition of 0.5 percent phenol. Phenol in a concentration of 0.5 percent is also used as the preservative in the finished vaccine. The vaccine contains 8 units of each serotype antigen (Ogawa and Inaba) per milliliter.

Cholera vaccine may be injected intracutaneously (intradermally), subcutaneously or intramuscularly.



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