Diamox Sequels

DRUG DESCRIPTION

DIAMOX SEQUELS (Acetazolamide Extended-Release Capsules) are an inhibitor of the enzyme carbonic anhydrase.

DIAMOX is a white to faintly yellowish white crystalline, odorless powder, weakly acidic, very slightly soluble in water and slightly soluble in alcohol. The chemical name for DIAMOX is N-(5-Sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide and has the following chemical structure:

DIAMOX SEQUELS (Acetazolamide) structural formula illustration

MW 222.24........C4H6N403S2

DIAMOX SEQUELS (acetazolamide xr) are extended-release capsules, for oral administration, each containing 500 mg of acetazolamide and the following inactive ingredients:

Microcrystalline cellulose, sodium lauryl sulfate and talc.

The ingredients in the capsule shell are D&C red no. 28, D&C yellow no. 10, FD&C red no. 40, gelatin and titanium dioxide.

The ingredients in the imprinting ink are D&C yellow no. 10 aluminum lake, FD&C blue no. 1 aluminum lake, FD&C blue no. 2 aluminum lake, FD&C red no. 40 aluminum lake, pharmaceutical glaze, propylene glycol and synthetic iron oxide.

What are the possible side effects of acetazolamide (Diamox, Diamox Sequels)?

If you experience any of the following serious side effects, stop taking acetazolamide and seek emergency medical attention:

  • an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
  • a sore throat or a fever;
  • unusual bleeding or bruising;
  • side or groin pain;
  • tingling or tremors in your hands or feet; or
  • a rash.

Other, less serious side effects may be more likely to occur. Continue to...

Read All Potential Side Effects and See Pictures of Diamox Sequels

What are the precautions when taking acetazolamide xr (Diamox Sequels)?

Before taking acetazolamide, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: adrenal gland problems (e.g., Addison's disease), low blood levels of sodium or potassium, severe kidney disease, severe liver disease (e.g., cirrhosis), certain metabolic problems (e.g., hyperchloremic acidosis).

Before using this medication, tell your doctor or pharmacist your medical history, especially of: breathing problems (e.g., emphysema, chronic...

Read All Potential Precautions of Diamox Sequels


Diamox Sequels Consumer (continued)

SIDE EFFECTS: Dizziness, lightheadedness, and an increased amount of urine may occur, especially during the first few days as your body adjusts to the medication. Blurred vision, dry mouth, drowsiness, loss of appetite, stomach upset, headache and tiredness may also occur. If any of these symptoms persist or worsen, notify your doctor or pharmacist.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately if any of these very unlikely but serious side effects occur: increased body hair, hearing loss, ringing in the ears, unusual tiredness, persistent nausea/vomiting, severe stomach/abdominal pain.

Seek immediate medical attention if any of these unlikely but very serious side effects occur: easy bleeding/bruising, fast/irregular heartbeat, signs of infection (e.g., fever, persistent sore throat), mental/mood changes (e.g., confusion, difficulty concentrating), severe muscle cramps/pain, tingling of the hands/feet, blood in the urine, dark urine, painful urination, yellowing of the eyes/skin.

A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: blisters/sores in the mouth, rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS: Before taking acetazolamide, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: adrenal gland problems (e.g., Addison's disease), low blood levels of sodium or potassium, severe kidney disease, severe liver disease (e.g., cirrhosis), certain metabolic problems (e.g., hyperchloremic acidosis).

Before using this medication, tell your doctor or pharmacist your medical history, especially of: breathing problems (e.g., emphysema, chronic bronchitis), high levels of calcium, dehydration, diabetes mellitus, gout, narrow-angle glaucoma, overactive thyroid (hyperthyroidism).

While this medication can help you get used to high altitudes and help you tolerate quick climbs, it cannot completely prevent serious altitude sickness. Symptoms of serious altitude sickness may include: severe shortness of breath, mental/mood changes (e.g., confusion, difficulty concentrating), lack of coordination/staggering walk, extreme tiredness, severe headache.

If you develop any of these symptoms, it is very important that you descend to a lower altitude as quickly as possible to prevent serious, possibly fatal problems.

This drug may make you dizzy or drowsy or cause blurred vision. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely. Limit alcoholic beverages.

To minimize dizziness and lightheadedness, get up slowly when rising from a seated or lying position.

This drug may infrequently make your blood sugar levels rise, causing or worsening diabetes. Tell your doctor immediately if you develop symptoms of high blood sugar such as increased thirst or tiredness.

If you already have diabetes, be sure to check your blood sugar levels regularly. This medication may also cause your blood sugar levels to fall. Symptoms of low blood sugar include fast/pounding heartbeat, shakiness, hunger and sweating. It is a good habit to carry glucose tablets or gel to treat low blood sugar. If you are in a situation where you don't have these reliable forms of glucose, eat a quick source of sugar such as table sugar, honey, or candy, or drink a glass of orange juice or non-diet soda to quickly raise your blood sugar level. Tell your doctor immediately about the reaction.

This medication may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths and sunlamps. Use a sunscreen and wear protective clothing when outdoors.

This medication should not be used in children less than 12 because it may affect normal growth.

This medication should be used with caution in the elderly because they may be more sensitive to its side effects, especially low potassium or sodium levels.

This medication should be used during pregnancy only if clearly needed. Discuss the risks and benefits with your doctor.

This medication passes into breast milk but is unlikely to harm a nursing infant. Consult your doctor before breast-feeding.


Diamox Sequels Patient Information Including Side Effects

Brand Names: Diamox, Diamox Sequels

Generic Name: acetazolamide (Pronunciation: a SEET a ZOLE a mide)

  • What is acetazolamide (Diamox Sequels)?
  • What are the possible side effects of acetazolamide (Diamox Sequels)?
  • What is the most important information I should know about acetazolamide (Diamox Sequels)?
  • Who should not take acetazolamide (Diamox Sequels)?
  • How should I take acetazolamide (Diamox Sequels)?
  • What happens if I miss a dose (Diamox Sequels)?
  • What happens if I overdose (Diamox Sequels)?
  • What should I avoid while taking acetazolamide (Diamox Sequels)?
  • What other drugs will affect acetazolamide (Diamox Sequels)?
  • Where can I get more information?

What is acetazolamide (Diamox Sequels)?

Acetazolamide is a carbonic anhydrase inhibitor. Carbonic anhydrase is a protein in your body. Acetazolamide reduces the activity of this protein.

Acetazolamide is used to treat glaucoma and to treat and to prevent acute mountain sickness (altitude sickness). It is also used as a part of some treatment plans for congestive heart failure and seizure disorders.

Acetazolamide may also be used for purposes other than those listed in this medication guide.

What are the possible side effects of acetazolamide (Diamox Sequels)?

If you experience any of the following serious side effects, stop taking acetazolamide and seek emergency medical attention:

  • an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
  • a sore throat or a fever;
  • unusual bleeding or bruising;
  • side or groin pain;
  • tingling or tremors in your hands or feet; or
  • a rash.

Other, less serious side effects may be more likely to occur. Continue to take acetazolamide and talk to your doctor if you experience

  • decreased appetite, nausea, vomiting, constipation, diarrhea, or changes in taste;
  • drowsiness, dizziness, fatigue, or weakness;
  • nervousness or mild tremor;
  • headache or confusion;
  • increased sensitivity of the skin to sunlight;
  • worsening gout;
  • loss of blood sugar control (if you are diabetic);
  • ringing in your ears or hearing problems; or
  • changes in your vision.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about acetazolamide (Diamox Sequels)?

Call your doctor immediately if you experience a sore throat, fever, unusual bleeding or bruising, tingling or tremors in your hands or feet, pain in your side or groin, or a rash. These symptoms could be early signs of a serious side effect.

Use caution when driving, operating machinery, or performing other hazardous activities. Acetazolamide may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.

Avoid prolonged exposure to sunlight. Acetazolamide may increase the sensitivity of your skin to sunlight. Use a sunscreen and wear protective clothing when exposure to the sun is unavoidable.

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