Dapsone

DRUG DESCRIPTION

Dapsone-USP, 4,4'-diaminodiphenylsulfone (DDS) is a primary treatment for Dermatitis herpetiformis. It is an antibacterial drug for susceptible cases of leprosy. It is a white, odorless crystalline powder, practically insoluble in water and insoluble in fixed and vegetable oils.

Dapsone is issued on prescription in tablets of 25 and 100 mg. for oral use.

Inactive Ingredients: Colloidal silicone dioxide, magnesium stearate, microcrystalline cellulose, and corn starch.

What are the possible side effects of dapsone ()?

In rare cases, dapsone has been associated with serious, and sometimes fatal blood and/or liver problems. Contact your doctor immediately if you experience a sore throat, fever, pale skin, bruising or pinpoint red spots on the skin, or yellowing of the skin or eyes. These may be symptoms of blood or liver problems.

Contact your doctor immediately if you develop a rash while taking dapsone. In rare cases, dapsone has been associated with serious, and sometimes fatal, skin reactions.

If you experience any of the following serious side effects, seek...

Read All Potential Side Effects and See Pictures of Dapsone

What are the precautions when taking dapsone (Dapsone)?

Before taking dapsone, tell your doctor or pharmacist if you are allergic to it; or to similar drugs such as sulfoxone; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have a certain medical condition. Before using this medicine, consult your doctor or pharmacist if you have: severe anemia.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: certain blood disorders (e.g., G6PD deficiency, methemoglobin reductase deficiency), liver disease, severe heart disease, severe lung disease, serious infection, very high blood sugar (diabetic ketosis).

If using...

Read All Potential Precautions of Dapsone


Dapsone Consumer (continued)

SIDE EFFECTS: Nausea, vomiting, loss of appetite, dizziness, or blurred vision may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately if any of these unlikely but serious side effects occur: unusually fast heartbeat, unusually fast breathing, bluish lips/skin, chest pain, mental/mood changes, muscle weakness, difficulty urinating.

This drug may rarely cause very serious low blood counts (bone marrow suppression) or liver disease. Seek immediate medical attention if you develop signs of an infection (e.g., fever, chills, persistent sore throat), easy bruising/bleeding, unusual tiredness, pale skin, yellowing eyes/skin, dark urine, stomach/abdominal pain.

Dapsone can commonly cause a rash that is usually not serious. However, you may not be able to tell it apart from a rare rash that could be a sign of a severe reaction. Therefore, seek immediate medical attention if you develop any rash.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS: Before taking dapsone, tell your doctor or pharmacist if you are allergic to it; or to similar drugs such as sulfoxone; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have a certain medical condition. Before using this medicine, consult your doctor or pharmacist if you have: severe anemia.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: certain blood disorders (e.g., G6PD deficiency, methemoglobin reductase deficiency), liver disease, severe heart disease, severe lung disease, serious infection, very high blood sugar (diabetic ketosis).

If using this drug to treat Hansen's disease, note that as your immune system helps fight the infection, you may notice skin sores worsening, and numbness/pain/tingling or muscle weakness. This may require special treatment, so tell your doctor immediately if these symptoms occur.

This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

This medication passes into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breast-feeding.


Dapsone Patient Information Including Side Effects

Brand Names:

Generic Name: dapsone (Pronunciation: DAP sone)

  • What is dapsone ?
  • What are the possible side effects of dapsone ?
  • What is the most important information I should know about dapsone ?
  • What should I discuss with my healthcare provider before taking dapsone ?
  • How should I take dapsone ?
  • What happens if I miss a dose ?
  • What happens if I overdose ?
  • What should I avoid while taking dapsone ?
  • What other drugs will affect dapsone ?
  • Where can I get more information?

What is dapsone ?

Dapsone is an antiinfective medication.

Dapsone is used in the treatment of dermatitis herpetiformis (a skin condition) and leprosy (Hansen's disease).

Dapsone may also be used for purposes other than those listed in this medication guide.

What are the possible side effects of dapsone ?

In rare cases, dapsone has been associated with serious, and sometimes fatal blood and/or liver problems. Contact your doctor immediately if you experience a sore throat, fever, pale skin, bruising or pinpoint red spots on the skin, or yellowing of the skin or eyes. These may be symptoms of blood or liver problems.

Contact your doctor immediately if you develop a rash while taking dapsone. In rare cases, dapsone has been associated with serious, and sometimes fatal, skin reactions.

If you experience any of the following serious side effects, seek emergency medical attention or contact your doctor immediately:

  • an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
  • bluish skin color;
  • muscle weakness;
  • numbness or tingling;
  • abdominal pain;
  • difficulty breathing;
  • dark colored urine or pale colored stools; or
  • unusual tiredness.

Other, less serious side effects may be more likely to occur. Notify your doctor if you experience

  • nausea or vomiting;
  • blurred vision;
  • ringing in the ears;
  • headache;
  • insomnia; or
  • increased sensitivity of the skin to sunlight.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about dapsone ?

In rare cases, dapsone has been associated with serious, and sometimes fatal blood and liver problems. Contact your doctor immediately if you experience a sore throat, fever, pale skin, bruising or pinpoint red spots on the skin, or yellowing of the skin or eyes. These may be symptoms of blood or liver problems.

Contact your doctor immediately if you develop a rash while taking dapsone. In rare cases, dapsone has been associated with serious, and sometimes fatal, skin reactions.

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