Cutivate Lotion

DRUG DESCRIPTION

CUTIVATE® (fluticasone propionate) Lotion, 0.05% contains fluticasone propionate [S(fluoromethyl)6?,9-difluoro-11?,17-dihydroxy-16?-methyl-3-oxoandrosta-1,4-diene-17?carbothioate, 17-propionate], a synthetic fluorinated corticosteroid, for topical dermatologic use. The topical corticosteroids constitute a class of primarily synthetic steroids used as antiinflammatory and antipruritic agents.

Chemically, fluticasone propionate is C25H31F3O5S. It has the following structural formula:

CUTIVATE (fluticasone propionate) Structural Formula Illustration

Fluticasone propionate is a white to off-white powder with a molecular weight of 500.6. It is practically insoluble in water, freely soluble in dimethyl sulfoxide and dimethylformamide, and slightly soluble in methanol and 95% ethanol.

Each gram of CUTIVATE® Lotion contains 0.5mg fluticasone propionate in a base of cetostearyl alcohol, isopropyl myristate, propylene glycol, cetomacrogol 1000, dimethicone 360, citric acid, sodium citrate, and purified water, with imidurea, methylparaben, and propylparaben as preservatives.

What are the possible side effects of fluticasone topical (Cutivate)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have severe irritation of any treated skin, or if you show signs of absorbing fluticasone topical through your skin, such as:

  • blurred vision, or seeing halos around lights;
  • mood changes;
  • sleep problems (insomnia);
  • weight gain, puffiness in your face; or
  • ...

Read All Potential Side Effects and See Pictures of Cutivate Lotion »


Cutivate Lotion Patient Information Including Side Effects

Brand Names: Cutivate

Generic Name: fluticasone topical (Pronunciation: floo TIK a sone)

  • What is fluticasone topical (Cutivate Lotion)?
  • What are the possible side effects of fluticasone topical (Cutivate Lotion)?
  • What is the most important information I should know about fluticasone topical (Cutivate Lotion)?
  • What should I discuss with my healthcare provider before using fluticasone topical (Cutivate Lotion)?
  • How should I use fluticasone topical (Cutivate Lotion)?
  • What happens if I miss a dose (Cutivate Lotion)?
  • What happens if I overdose (Cutivate Lotion)?
  • What should I avoid while using fluticasone topical (Cutivate Lotion)?
  • What other drugs will affect fluticasone topical (Cutivate Lotion)?
  • Where can I get more information?

What is fluticasone topical (Cutivate Lotion)?

Fluticasone is a topical (for the skin) steroid. It reduces the actions of chemicals in the body that cause inflammation, redness, and swelling.

Fluticasone topical is used to treat the inflammation and itching caused by a number of skin conditions such as allergic reactions, eczema, and psoriasis.

Fluticasone topical should not be used to treat rosacea, severe acne, or viral skin infections such as chickenpox or herpes. Fluticasone should not be used on a child younger than 12 years old.

Fluticasone topical may also be used for other purposes not listed in this medication guide.

What are the possible side effects of fluticasone topical (Cutivate Lotion)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have severe irritation of any treated skin, or if you show signs of absorbing fluticasone topical through your skin, such as:

  • blurred vision, or seeing halos around lights;
  • mood changes;
  • sleep problems (insomnia);
  • weight gain, puffiness in your face; or
  • muscle weakness, feeling tired.

Less serious side effects may include:

  • mild skin itching, burning, peeling, or dryness;
  • changes in color of treated skin;
  • headache;
  • thinning or softening of your skin;
  • skin rash or irritation around your mouth;
  • swollen hair follicles;
  • blisters, pimples, or crusting of treated skin; or
  • stretch marks.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about fluticasone topical (Cutivate Lotion)?

Use this medication exactly as it has been prescribed by your doctor. Do not use the medication in larger amounts or for longer than recommended. Topical steroid medicine can be absorbed through the skin, which may cause steroid side effects throughout the body.

Do not cover treated skin areas with a bandage or other covering. Covering the skin that is treated with fluticasone topical can increase the amount of medicine your skin absorbs, which may lead to unwanted side effects.

Do not use this medication on a child younger than 12 years old without the advice of a doctor. Children are more likely to absorb large amounts of a topical steroid through the skin. Steroid absorption in children may cause unwanted side effects, or a delay in growth with long-term use. Talk with your doctor if you think your child is not growing at a normal rate while using this medication over a long treatment period.

Contact your doctor if your condition does not improve after 2 weeks of using this medicine, or if you develop signs of a bacterial, fungal, or viral skin infection.

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