Feridex I.V.

DRUG DESCRIPTION

Feridex I.V. (ferumoxides injectable solution) is a sterile aqueous colloid of superparamagnetic iron oxide associated with dextran for intravenous (i.v.) administration as a magnetic resonance imaging contrast media. Chemically, ferumoxides is a non-stoichiometric magnetite, of average formula FeO1.44. Each milliliter of Feridex I.V. (ferumoxides injectable solution) contains 11.2 milligrams of iron and 61.3 milligrams of mannitol at a pH of 5 to 9. The formulation also contains dextran (5.69.1 mg/mL) and citrate (0.250.53 mg/mL).

The osmolality is approximately 340 mOsm/kg; specific gravity is 1.04. Feridex I.V. (ferumoxides injectable solution) is a black to reddish-brown aqueous colloid.



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