Zymar

DRUG DESCRIPTION

ZYMAR® (gatifloxacin ophthalmic solution) 0.3% is a sterile ophthalmic solution. It is an 8-methoxy fluoroquinolone anti-infective for topical ophthalmic use.

Structure and Empirical Formula:

ZYMAR® (gatifloxacin ophthalmic solution) structural formula illustration

C19H22FN3O4 • 1.5 H2O                       Mol Wt 402.42

Chemical Name: (±)-1-cyclopropyl-6-fluoro-1, 4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid sesquihydrate

Contains:

Active: gatifloxacin 0.3% (3 mg/mL).

Preservative: benzalkonium chloride 0.005%.

Inactives: edetate disodium; purified water and sodium chloride. May contain hydrochloric acid and/or sodium hydroxide to adjust pH to approximately 6.

ZYMAR® (gatifloxacin ophthalmic solution) is a sterile, clear, pale yellow colored isotonic unbuffered solution. It has an osmolality of 260-330 mOsm/kg.

What are the possible side effects of gatifloxacin ophthalmic (Zymar)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; slow heart rate, weak pulse, fainting; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

  • severe swelling, burning, redness, or discomfort in or around your eye;
  • eye pain, vision changes, increased sensitivity of your eyes to light;
  • signs of new infection, such as drainage, crusting, or oozing of your eyes or...

Read All Potential Side Effects and See Pictures of Zymar »

What are the precautions when taking gatifloxacin ophthalmic solution (Zymar)?

Before using this medication, tell your doctor or pharmacist if you are allergic to it; or to quinolone antibiotics (such as ciprofloxacin); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: contact lens use.

Your vision may be temporarily blurred or unstable after applying this drug. Do not drive, use machinery, or do any activity that requires clear vision until you are sure you can perform such activities safely.

Use of this medication for prolonged or repeated periods may result in a secondary infection.

This drug should be used...

Read All Potential Precautions of Zymar »


Zymar Consumer (continued)

SIDE EFFECTS: Blurred vision, watery eyes, headache, eye irritation/pain/dryness/redness, bad taste in mouth may occur. If any of these effects persist or worsen, inform your doctor.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately if any of these unlikely but serious side effects occur: persistent eye redness, swelling of the eye or eyelid.

An allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include: rash, itching/swelling (especially of the face/tongue/throat), dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS: Before using this medication, tell your doctor or pharmacist if you are allergic to it; or to quinolone antibiotics (such as ciprofloxacin); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: contact lens use.

Your vision may be temporarily blurred or unstable after applying this drug. Do not drive, use machinery, or do any activity that requires clear vision until you are sure you can perform such activities safely.

Use of this medication for prolonged or repeated periods may result in a secondary infection.

This drug should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor.

It is not known if this medication is passes into breast milk. Consult your doctor before breast-feeding.


Zymar Patient Information Including Side Effects

Brand Names: Zymar

Generic Name: gatifloxacin ophthalmic (Pronunciation: GAT i FLOX a sin off THAL mik)

  • What is gatifloxacin ophthalmic (Zymar)?
  • What are the possible side effects of gatifloxacin ophthalmic (Zymar)?
  • What is the most important information I should know about gatifloxacin ophthalmic (Zymar)?
  • What should I discuss with my healthcare provider before using gatifloxacin ophthalmic (Zymar)?
  • How should I use gatifloxacin ophthalmic (Zymar)?
  • What happens if I miss a dose (Zymar)?
  • What happens if I overdose (Zymar)?
  • What should I avoid while using gatifloxacin ophthalmic (Zymar)?
  • What other drugs will affect gatifloxacin ophthalmic (Zymar)?
  • Where can I get more information?

What is gatifloxacin ophthalmic (Zymar)?

Gatifloxacin is an antibiotic in a group of drugs called fluoroquinolones (flor-o-KWIN-o-lones). Gatifloxacin fights bacteria in the body.

Gatifloxacin ophthalmic (for the eyes) is used to treat eye infections caused by bacteria.

Gatifloxacin ophthalmic may also be used for other purposes not listed in this medication guide.

What are the possible side effects of gatifloxacin ophthalmic (Zymar)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; slow heart rate, weak pulse, fainting; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

  • severe swelling, burning, redness, or discomfort in or around your eye;
  • eye pain, vision changes, increased sensitivity of your eyes to light;
  • signs of new infection, such as drainage, crusting, or oozing of your eyes or eyelids;
  • the first sign of any skin rash, no matter how mild.

Less serious side effects may include:

  • mild itching, burning, redness, or irritation;
  • watery eyes;
  • puffy eyelids;
  • headache;
  • unpleasant taste in your mouth after using the drops.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about gatifloxacin ophthalmic (Zymar)?

You should not use this medication if you allergic to gatifloxacin

Before using this medication, tell your doctor if you have ever had an allergic reaction to gatifloxacin (Tequin) or similar medications such as levofloxacin (Levaquin), lomefloxacin (Maxaquin), moxifloxacin (Avelox), ofloxacin (Floxin), norfloxacin (Noroxin), and others.

Avoid wearing contact lenses while you still have active symptoms of the eye infection you are treating. Do not use other eye drops or medications during treatment unless otherwise directed by your doctor.

Do not allow the dropper tip to touch any surface, including the eyes or hands. If the dropper becomes contaminated it could cause an infection in your eye, which can lead to vision loss or serious damage to the eye.

Call your doctor at once if you have a serious side effect such as severe swelling, burning, redness, or discomfort, eye pain or vision changes, signs of new eye infection (drainage, crusting, or oozing), or the first sign of any skin rash, no matter how mild.

Related Drug Centers
  • Zymar


Related Drugs Index: