DiaBeta

DRUG DESCRIPTION

Dia?etaź (glyburide) is an oral blood-glucose-lowering drug of the sulfonylurea class. It is a white, crystalline compound, formulated as tablets of 1.25 mg, 2.5 mg, and 5 mg strengths for oral administration. Dia?eta tablets USP contain the active ingredient glyburide and the following inactive ingredients: dibasic calcium phosphate USP, magnesium stearate NF, microcrystalline cellulose NF, sodium alginate NF, talc USP. Dia?eta (glyburide tablets) 1.25 mg tablets USP also contain D&C Yellow #10 Aluminum Lake and FD&C Red #40 Aluminum Lake. Dia?eta (glyburide tablets) 2.5 mg tablets USP also contain FD&C Red #40 Aluminum Lake. Dia?eta (glyburide tablets) 5 mg tablets USP also contain D&C Yellow #10 Aluminum Lake, and FD&C Blue #1. Chemically, Dia?eta (glyburide tablets) is identified as 1-[[p-[2-(5-Chloro-o-anisamido)ethyl]phenyl]sulfonyl]-3-cyclohexylurea.

The CAS Registry Number is 10238-21-8.

The structural formula is:

Dia?eta (glyburide) Structural Formula Illustration

The molecular weight is 493.99. The aqueous solubility of Dia?eta (glyburide tablets) increases with pH as a result of salt formation.

What are the possible side effects of glyburide (DiaBeta, Glynase PresTab, Micronase)?

Stop using glyburide and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
  • pale skin, confusion or weakness;
  • easy bruising or bleeding, purple or red pinpoint spots under...

Read All Potential Side Effects and See Pictures of DiaBeta »


DiaBeta Patient Information Including Side Effects

Brand Names: DiaBeta, Glynase PresTab, Micronase

Generic Name: glyburide (Pronunciation: GLYE bue ride)

  • What is glyburide (DiaBeta)?
  • What are the possible side effects of glyburide (DiaBeta)?
  • What is the most important information I should know about glyburide (DiaBeta)?
  • What should I discuss with my health care provider before taking glyburide (DiaBeta)?
  • How should I take glyburide (DiaBeta)?
  • What happens if I miss a dose (DiaBeta)?
  • What happens if I overdose (DiaBeta)?
  • What should I avoid while taking glyburide (DiaBeta)?
  • What other drugs will affect glyburide (DiaBeta)?
  • Where can I get more information?

What is glyburide (DiaBeta)?

Glyburide is an oral diabetes medicine that help control blood sugar levels.

Glyburide is used to treat type 2 diabetes (non-insulin dependent).

This medication is not for treating type 1 diabetes.

Glyburide may also be used for other purposes not listed in this medication guide.

What are the possible side effects of glyburide (DiaBeta)?

Stop using glyburide and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
  • pale skin, confusion or weakness;
  • easy bruising or bleeding, purple or red pinpoint spots under your skin; or
  • headache, trouble concentrating, memory problems, feeling unsteady, hallucinations, fainting, seizure, shallow breathing or breathing that stops.

Less serious side effects may include:

  • mild nausea, heartburn, feeling full;
  • joint or muscle pain;
  • blurred vision; or
  • mild itching or skin rash.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about glyburide (DiaBeta)?

You should not use this medication if you are allergic to glyburide, if you are being treated with bosentan (Tracleer), if you have type 1 (insulin-dependent) diabetes, or if you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin).

Before taking glyburide, tell your doctor if you are allergic to sulfa drugs, if you have been using insulin or chlorpropamide (Diabinese), or if you have hemolytic anemia (a lack of red blood cells), an enzyme deficiency G6PD, a nerve disorder, liver disease, or kidney disease.

Know the signs of low blood sugar (hypoglycemia) and how to recognize them. Always keep a source of sugar available in case you have symptoms of low blood sugar.

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  • Micronase
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