Halonate Halobetasol Propionate Ointment, 0.05% contains halobetasol propionate, a synthetic corticosteroid for topical dermatological use. The corticosteroids constitute a class of primarily synthetic steroids used topically as an anti-inflammatory and anti-pruritic agent.

Chemically halobetasol propionate is 21-chloro- 6?, 9-dif luoro-11?,17-dihyd roxy-16?- methylpregna-1,4-diene-3-20-dione, 17-propionate, C₂₅H₃₁CIF₂O₅. It has the following structural formula:

Halobetasol propionate has the molecular weight of 485 It is a white crystalline powder insoluble in water

Each gram of Halobetasol Propionate Ointment contains 0 5 mg/g of halobetasol propionate in a base of aluminum stearate. beeswax, pentaerythritol cocoate. petrolatum, propylene glycol, sorbitan sesquioleate. and stearyl citrate