Synvisc

DRUG DESCRIPTION

SYNVISC® (hylan G-F 20) is an elastoviscous high molecular weight fluid containing hylan A and hylan B polymers produced from chicken combs. Hylans are derivatives of hyaluronan (sodium hyaluronate). Hylan G-F 20 is unique in that the hyaluronan is chemically crosslinked. Hyaluronan is a long-chain polymer containing repeating disaccharide units of Na-glucuronate-Nacetylglucosamine.

What are the possible side effects of hylan G-F 20 (Synvisc)?

Notify your doctor immediately if you experience a rare but serious allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives) to hylan G-F 20.

Other less serious side effects may also occur. Talk to your doctor if you experience

  • temporary pain or swelling of the affected joint;
  • rash or bruising at the injection site;
  • headache; or
  • upset stomach.

Side effects other than those listed here may also occur. Talk to your doctor about any...

Read All Potential Side Effects and See Pictures of Synvisc »

What are the precautions when taking hylan g-f 20 (Synvisc)?

Before using hyaluronate, tell your doctor or pharmacist if you are allergic to it; or to bird proteins, feathers, or egg products; or if you have any other allergies. This product may contain inactive ingredients (such as latex found in the rubber syringe cap of some brands), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: knee joint infections, skin infections/problems in the area around the injection site, circulation problems in the legs.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is unknown whether this drug passes into breast milk....

Read All Potential Precautions of Synvisc »


Synvisc Consumer (continued)

SIDE EFFECTS: See also How to Use section.

Pain, swelling, redness/warmth/bruising at the injection site, or headache may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: back pain, severe headache, fast/pounding heartbeat, fever, tingling skin.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS: Before using hyaluronate, tell your doctor or pharmacist if you are allergic to it; or to bird proteins, feathers, or egg products; or if you have any other allergies. This product may contain inactive ingredients (such as latex found in the rubber syringe cap of some brands), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: knee joint infections, skin infections/problems in the area around the injection site, circulation problems in the legs.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is unknown whether this drug passes into breast milk. Consult your doctor before breast-feeding.


Synvisc Patient Information Including Side Effects

Brand Names: Synvisc

Generic Name: hylan G-F 20 (Pronunciation: HI lan G F 20)

  • What is hylan G-F 20 (Synvisc)?
  • What are the possible side effects of hylan G-F 20 (Synvisc)?
  • What is the most important information I should know about hylan G-F 20 (Synvisc)?
  • What should I discuss with my health care provider before using hylan G-F 20 (Synvisc)?
  • How should I use hylan G-F 20 (Synvisc)?
  • What happens if I miss a dose (Synvisc)?
  • What happens if I overdose (Synvisc)?
  • What should I avoid while using hylan G-F 20 (Synvisc)?
  • What other drugs will affect hylan G-F 20 (Synvisc)?
  • Where can I get more information?

What is hylan G-F 20 (Synvisc)?

Hylan G-F 20 is similar to synovial fluid, a substance that occurs naturally in the joints. Synovial fluid acts as a lubricant and shock absorber.

Hylan G-F 20 is injected into the knee joints for the treatment of pain in individuals with osteoarthritis.

Hylan G-F 20 may also be used for purposes other than those listed here.

What are the possible side effects of hylan G-F 20 (Synvisc)?

Notify your doctor immediately if you experience a rare but serious allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives) to hylan G-F 20.

Other less serious side effects may also occur. Talk to your doctor if you experience

  • temporary pain or swelling of the affected joint;
  • rash or bruising at the injection site;
  • headache; or
  • upset stomach.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about hylan G-F 20 (Synvisc)?

Talk to your doctor before using hylan G-F 20 if you have an allergy to birds or bird products, feathers, or egg products.

Related Drug Centers
  • Synvisc


Related Drugs Index: