Lanoxin

DRUG DESCRIPTION

Lanoxin (digoxin) is one of the cardiac (or digitalis) glycosides, a closely related group of drugs having in common specific effects on the myocardium. These drugs are found in a number of plants. Digoxin is extracted from the leaves of Digitalis lanata. The term “digitalis” is used to designate the whole group of glycosides. The glycosides are composed of 2 portions: a sugar and a cardenolide (hence “glycosides”).

Digoxin is described chemically as (3?,5?,12?)-3-[(O-2,6-dideoxy-?-D-ribo-hexopyranosyl(1?4)-O-2,6-dideoxy-?-D-ribo-hexopyranosyl-(1?4)-2,6-dideoxy-?-D-ribohexopyranosyl)oxy]-12,14-dihydroxy-card-20(22)-enolide. Its molecular formula is C41H64O14, its molecular weight is 780.95, and its structural formula is:

Lanoxin (digoxin) Structural Formula  Illustration

Digoxin exists as odorless white crystals that melt with decomposition above 230°C. The drug is practically insoluble in water and in ether; slightly soluble in diluted (50%) alcohol and in chloroform; and freely soluble in pyridine.

Lanoxin (digoxin tablets) is supplied as 125-mcg (0.125-mg) or 250-mcg (0.25-mg) tablets for oral administration. Each tablet contains the labeled amount of digoxin USP and the following inactive ingredients: corn and potato starches, lactose, and magnesium stearate. In addition, the dyes used in the 125-mcg (0.125-mg) tablets are D&C Yellow No. 10 and FD&C Yellow No. 6.

What are the possible side effects of digoxin (Digitek, Lanoxicaps, Lanoxin)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

  • fast, slow, or uneven heart rate;
  • bloody or black, tarry stools;
  • blurred vision, yellowed vision; or
  • confusion, hallucinations, unusual thoughts or behavior.

Less serious side effects may include:

  • mild nausea,...

Read All Potential Side Effects and See Pictures of Lanoxin »

What are the precautions when taking digoxin tablets (Lanoxin)?

Before using alcaftadine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: contact lens use.

After you apply this drug, your vision may be temporarily unclear. Do not drive, use machinery, or do any activity that requires clear vision until you are sure you can perform such activities safely.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

If you develop an eye infection...

Read All Potential Precautions of Lanoxin »


Lanoxin Consumer (continued)

SIDE EFFECTS: Mild and temporary burning/stinging of the eyes may occur when you apply this medication. If this effect persists or worsens, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS: Before using alcaftadine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: contact lens use.

After you apply this drug, your vision may be temporarily unclear. Do not drive, use machinery, or do any activity that requires clear vision until you are sure you can perform such activities safely.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

If you develop an eye infection or eye injury, or require eye surgery, ask your doctor if you should continue to use your current bottle of alcaftadine eye drops or start a new bottle.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding.


Lanoxin Patient Information Including Side Effects

Brand Names: Digitek, Lanoxicaps, Lanoxin

Generic Name: digoxin (oral) (Pronunciation: di JOX in)

  • What is digoxin (Lanoxin)?
  • What are the possible side effects of digoxin (Lanoxin)?
  • What is the most important information I should know about digoxin (Lanoxin)?
  • What should I discuss with my healthcare provider before taking digoxin (Lanoxin)?
  • How should I take digoxin (Lanoxin)?
  • What happens if I miss a dose (Lanoxin)?
  • What happens if I overdose (Lanoxin)?
  • What should I avoid while taking digoxin (Lanoxin)?
  • What other drugs will affect digoxin (Lanoxin)?
  • Where can I get more information?

What is digoxin (Lanoxin)?

Digoxin is derived from the leaves of a digitalis plant. Digoxin helps make the heart beat stronger and with a more regular rhythm.

Digoxin is used to treat congestive heart failure.

Digoxin is also used to treat atrial fibrillation, a heart rhythm disorder of the atria (the upper chambers of the heart that allow blood to flow into the heart).

Digoxin may also be used for other purposes not listed in this medication guide.

What are the possible side effects of digoxin (Lanoxin)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

  • fast, slow, or uneven heart rate;
  • bloody or black, tarry stools;
  • blurred vision, yellowed vision; or
  • confusion, hallucinations, unusual thoughts or behavior.

Less serious side effects may include:

  • mild nausea, vomiting, diarrhea;
  • feeling weak or dizzy;
  • headache;
  • enlarged breasts in men; or
  • mild skin rash.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about digoxin (Lanoxin)?

You should not use this medication if you are allergic to digoxin, or if you have ventricular fibrillation (a heart rhythm disorder of the ventricles, or lower chambers of the heart that allow blood to flow out of the heart).

Before using digoxin, tell your doctor if you have certain heart conditions, especially "AV block" (unless you have a pacemaker), or a recent history of heart attack. Also tell your doctor if you have kidney disease, a thyroid disorder, an electrolyte imbalance (such as low levels of calcium, potassium, or magnesium in your blood), or if you are malnourished or have recently been sick with vomiting or diarrhea.

Keep taking digoxin as directed, even if you feel well. Get your prescription refilled before you run out of medicine completely.

Do not stop taking digoxin without first talking to your doctor. Stopping suddenly may make your condition worse.

Avoid becoming overheated or dehydrated during exercise, in hot weather, or by not drinking enough fluids. Digoxin overdose can occur more easily if you are dehydrated.

There are many other medicines that can interact with digoxin. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.

Related Drug Centers
  • Digitek
  • Lanoxin Tablets


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