Maxaquin

(Generic versions may still be available.)

DRUG DESCRIPTION

Maxaquin (lomefloxacin HCl) is a synthetic broad-spectrum antimicrobial agent for oral administration. Lomefloxacin HCl, a difluoroquinolone, is the monohydrochloride salt of ()-1-ethyl-6, 8-difluoro-1, 4-dihydro-7- (3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid. Its empirical formula is C17H19F2N3O3 HCl, and its structural formula is:

Lomefloxacin HCl is a white to pale yellow powder with a molecular weight of 387.8. It is slightly soluble in water and practically insoluble in alcohol. Lomefloxacin HCl is stable to heat and moisture but is sensitive to light in dilute aqueous solution.

Maxaquin (lomefloxacin hcl) is available as a film-coated tablet formulation containing 400 mg of lomefloxacin base, present as the hydrochloride salt. The base content of the hydrochloride salt is 90.6%. The inactive ingredients are carboxymethylcellulose calcium, hydroxypropyl cellulose, hypromellose, lactose, magnesium stearate, polyethylene glycol, polyoxyl 40 stearate, and titanium dioxide.

What are the possible side effects of lomefloxacin (Maxaquin)?

If you experience any of the following serious side effects, stop taking lomefloxacin and seek emergency medical attention or contact your doctor immediately:

  • an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
  • seizures;
  • confusion or hallucinations;
  • liver damage (yellowing of the skin or eyes, nausea, abdominal pain or discomfort, unusual bleeding or bruising, severe fatigue); or
  • muscle or joint pain.

If...

Read All Potential Side Effects and See Pictures of Maxaquin


Maxaquin Patient Information Including Side Effects

Brand Names: Maxaquin

Generic Name: lomefloxacin (Pronunciation: loe me FLOX a sin)

  • What is lomefloxacin (Maxaquin)?
  • What are the possible side effects of lomefloxacin (Maxaquin)?
  • What is the most important information I should know about lomefloxacin (Maxaquin)?
  • What should I discuss with my healthcare provider before taking lomefloxacin (Maxaquin)?
  • How should I take lomefloxacin (Maxaquin)?
  • What happens if I miss a dose (Maxaquin)?
  • What happens if I overdose (Maxaquin)?
  • What should I avoid while taking lomefloxacin (Maxaquin)?
  • What other drugs will affect lomefloxacin (Maxaquin)?
  • Where can I get more information?

What is lomefloxacin (Maxaquin)?

Lomefloxacin is an antibiotic in a class of drugs called fluoroquinolones. It fights bacteria in the body.

Lomefloxacin is used to treat various bacterial infections, such as bronchitis and urinary tract infections.

Lomefloxacin may also be used for purposes other than those listed in this medication guide.

What are the possible side effects of lomefloxacin (Maxaquin)?

If you experience any of the following serious side effects, stop taking lomefloxacin and seek emergency medical attention or contact your doctor immediately:

  • an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
  • seizures;
  • confusion or hallucinations;
  • liver damage (yellowing of the skin or eyes, nausea, abdominal pain or discomfort, unusual bleeding or bruising, severe fatigue); or
  • muscle or joint pain.

If you experience any of the following less serious side effects, continue taking lomefloxacin and talk your doctor:

  • nausea, vomiting, or diarrhea;
  • headache, lightheadedness, or drowsiness;
  • ringing in the ears; or
  • increased sensitivity of the skin to sunlight.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What is the most important information I should know about lomefloxacin (Maxaquin)?

Take all of the lomefloxacin that has been prescribed for you even if you begin to feel better. Your symptoms may start to improve before the infection is completely treated.

Take lomefloxacin with a full glass of water (8 ounces). Drink several extra glasses of fluid each day to prevent lomefloxacin crystals from forming in the urine.

Lomefloxacin may make the skin more sensitive to sunlight, and a severe sunburn may result. Avoid exposure to both direct and indirect sunlight during therapy and for a few days after treatment ends. If you experience severe burning, redness, itching, swelling, or blistering, contact your doctor.

Do not take antacids that contain magnesium or aluminum (e.g., Tums or Rolaids), the ulcer medicine sucralfate (Carafate), or vitamin or mineral supplements that contain iron or zinc for a minimum of 2 hours before or 2 hours after a dose of lomefloxacin. Taking antacids, sucralfate, or vitamin or mineral supplements too close to a dose of lomefloxacin can greatly decrease the effects of the antibiotic.

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