Somatuline Depot


Somatuline Depot (lanreotide) Injection 60, 90 and 120 mg is a prolonged-release formulation for deep subcutaneous injection containing the drug substance lanreotide acetate, a synthetic octapeptide with a biological activity similar to naturally occurring somatostatin, and water for injection.

Somatuline Depot (lanreotide) is available as sterile, ready-to-use, pre-filled syringes containing lanreotide supersaturated bulk solution of 24.6% w/w lanreotide base.

Each syringe contains: Somatuline Depot 60 mg Somatuline Depot 90 mg Somatuline Depot 120 mg
Lanreotide acetate 79.8 mg 116.4 mg 155.5 mg
Water for injection 186.2 mg 271.6 mg 363 mg

Lanreotide acetate is a synthetic cyclical octapeptide analog of the natural hormone, somatostatin. Lanreotide acetate is chemically known as [cyclo S-S]-3-(2-naphthyl)-D-alanylL-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-L-threoninamide, acetate salt. Its molecular weight is 1096.34 (base) and its amino acid sequence is:

SOMATULINE® DEPOT (lanreotide)  Formula Illustration

For appearance of the formulation, see Dosage Forms and Strengths.

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