Lufyllin

DRUG DESCRIPTION

LUFYLLIN (dyphylline), a xanthine derivative, is a bronchodilator available for oral administration as tablets containing 200 mg and 400 mg of dyphylline. Other ingredients: magnesium stearate, microcrystalline cellulose.

Chemically, dyphylline is 7-(2,3-dihydroxypropyl)-theophylline, a white, extremely bitter, amorphous powder that is freely soluble in water and soluble in alcohol to the extent of 2 g/100 mL. Dyphylline forms a neutral solution that is stable in gastrointestinal fluids over a wide range of pH.

The molecular formula for dyphylline is C 10 H 14 N 4 O 4 with a molecular weight of 254.25. The structual formula is:

What are the possible side effects of dyphylline (Dilor, Dylix, Lufyllin, Neothylline)?

If you experience any of the following serious side effects, stop taking dyphylline and seek emergency medical attention:

  • an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
  • seizures;
  • increased or irregular heartbeats; or
  • severe nausea or vomiting.

Other, less serious side effects may occur although they are not common at appropriate doses. Continue to take dyphylline and talk to your doctor...

Read All Potential Side Effects and See Pictures of Lufyllin

What are the precautions when taking dyphylline (Lufyllin)?

Before using dyphylline, tell your doctor or pharmacist if you are allergic to it; or to theophylline, theobromine or caffeine; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: glaucoma, diabetes, heart problems (e.g., angina, irregular heartbeat), high blood pressure, kidney disease, seizures, stomach/intestinal ulcer, overactive thyroid (hyperthyroidism).

This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic...

Read All Potential Precautions of Lufyllin


Lufyllin Consumer (continued)

SIDE EFFECTS: Stomach pain/cramping, nausea, vomiting, diarrhea, loss of appetite, headache, trouble sleeping, irritability, restlessness, nervousness, shaking, flushing, and increased urination may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately if any of these unlikely but serious side effects occur: confusion, dizziness, mental/mood changes, muscle twitching/pain/tenderness, weakness, rapid breathing.

Tell your doctor immediately if any of these rare but very serious side effects occur: fainting, fast/slow/irregular heartbeat, vomit that looks like coffee grounds, dark/tarry stools, blood in urine, seizures.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, red/scaly skin, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS: Before using dyphylline, tell your doctor or pharmacist if you are allergic to it; or to theophylline, theobromine or caffeine; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: glaucoma, diabetes, heart problems (e.g., angina, irregular heartbeat), high blood pressure, kidney disease, seizures, stomach/intestinal ulcer, overactive thyroid (hyperthyroidism).

This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.

Liquid preparations of this product may contain sugar and/or alcohol. Caution is advised if you have diabetes, alcohol dependence, or liver disease. Ask your doctor or pharmacist about using this product safely.

Before having surgery, tell your doctor or dentist that you are using this medication.

Kidney function declines as you grow older. This medication is removed by the kidneys. Therefore, caution is advised when using this drug in the elderly because they may be more sensitive to its effects.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

This drug passes into breast milk and may have undesirable effects on a nursing infant (e.g., irritability). Consult your doctor before breast-feeding.


Lufyllin Patient Information Including Side Effects

Brand Names: Dilor, Dylix, Lufyllin, Neothylline

Generic Name: dyphylline (Pronunciation: dye FI lin)

  • What is dyphylline (Lufyllin)?
  • What are the possible side effects of dyphylline (Lufyllin)?
  • What is the most important information I should know about dyphylline (Lufyllin)?
  • Who should not take dyphylline (Lufyllin)?
  • How should I take dyphylline (Lufyllin)?
  • What happens if I miss a dose (Lufyllin)?
  • What happens if I overdose (Lufyllin)?
  • What should I avoid while taking dyphylline (Lufyllin)?
  • What other drugs will affect dyphylline (Lufyllin)?
  • Where can I get more information?

What is dyphylline (Lufyllin)?

Dyphylline is a bronchodilator. Dyphylline works in several ways: It relaxes muscles in your lungs and chest to allow more air in, it decreases the sensitivity of your lungs to allergens and other substances that cause inflammation, and it increases the contractions of your diaphragm to draw more air into the lungs.

Dyphylline is used to treat the symptoms of asthma, bronchitis, and emphysema.

Dyphylline may also be used for purposes other than those listed in this medication guide.

What are the possible side effects of dyphylline (Lufyllin)?

If you experience any of the following serious side effects, stop taking dyphylline and seek emergency medical attention:

  • an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
  • seizures;
  • increased or irregular heartbeats; or
  • severe nausea or vomiting.

Other, less serious side effects may occur although they are not common at appropriate doses. Continue to take dyphylline and talk to your doctor if you experience

  • slight nausea, decreased appetite, or weight loss;
  • restlessness, tremor, or insomnia; or
  • headache, lightheadedness, or dizziness.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about dyphylline (Lufyllin)?

Call your doctor right away if you experience nausea, vomiting, insomnia, restlessness, seizures, an increased heart rate, or a headache. These could be signs of too much dyphylline in your blood.

Do not start or stop smoking without your doctor's knowledge. Smoking may affect your dosage.

Do not take more of this medicine than is prescribed without consulting your doctor. Seek medical attention if you are having increasing difficulty breathing.

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