Miostat

DRUG DESCRIPTION

MIOSTAT® (carbachol intraocular solution, USP) is a sterile balanced salt solution of carbachol for intraocular injection. The active ingredient is represented by the chemical structure:

MIOSTAT® (carbachol) Structural formula Illustration

Established name: Carbachol

Chemical name: Ethanaminium, 2-[(aminocarbonyl)oxy]-N,N,N-trimethyl-, chloride.

Molecular Formula: C6H15CIN2O2

Molecular Weight: 182.65

Each mL contains: Active: carbachol 0.01%. Inactives: sodium chloride 0.64%, potassium chloride 0.075%, calcium chloride dihydrate 0.048%, magnesium chloride hexahydrate 0.03%, sodium acetate trihydrate 0.39%, sodium citrate dihydrate 0.17%, sodium hydroxide and/or hydrochloric acid (to adjust pH) and Water for Injection. pH range is 6.5-7.5.

What are the possible side effects of carbachol ophthalmic (Carbachol, Carboptic, Isopto Carbachol, Miostat)?

Contact your doctor immediately if you notice any decrease in vision or an increase in "floaters" in your visual field. Rarely, carbachol ophthalmic may cause retinal detachment. Retinal detachment can lead to blind spots, floaters in your visual field, and even blindness. Your doctor will want to check your retina before you use this medicine to determine if you have an increased risk of retinal detachment.

Other, less serious side effects may be more likely to occur. Continue to use carbachol...

Read All Potential Side Effects and See Pictures of Miostat »


Miostat Patient Information Including Side Effects

Brand Names: Carbachol, Carboptic, Isopto Carbachol, Miostat

Generic Name: carbachol ophthalmic (Pronunciation: KAR ba kall)

  • What is carbachol ophthalmic (Miostat)?
  • What are the possible side effects of carbachol ophthalmic (Miostat)?
  • What is the most important information I should know about carbachol ophthalmic (Miostat)?
  • What should I discuss with my healthcare provider before using carbachol ophthalmic (Miostat)?
  • How should I use carbachol ophthalmic (Miostat)?
  • What happens if I miss a dose (Miostat)?
  • What happens if I overdose (Miostat)?
  • What should I avoid while using carbachol ophthalmic (Miostat)?
  • What other drugs will affect carbachol ophthalmic (Miostat)?
  • Where can I get more information?

What is carbachol ophthalmic (Miostat)?

Carbachol ophthalmic reduces the pressure in the eye by increasing the amount of fluid that drains from the eye. Carbachol ophthalmic also causes the pupil to become smaller and reduces its response to light or dark conditions.

Carbachol ophthalmic is used to treat glaucoma by lowering the pressure inside the eye.

Carbachol ophthalmic may also be used for purposes other than those listed in this medication guide.

What are the possible side effects of carbachol ophthalmic (Miostat)?

Contact your doctor immediately if you notice any decrease in vision or an increase in "floaters" in your visual field. Rarely, carbachol ophthalmic may cause retinal detachment. Retinal detachment can lead to blind spots, floaters in your visual field, and even blindness. Your doctor will want to check your retina before you use this medicine to determine if you have an increased risk of retinal detachment.

Other, less serious side effects may be more likely to occur. Continue to use carbachol ophthalmic and talk to your doctor if you experience

  • burning, stinging, or tearing eyes;
  • decreased vision in poor light;
  • headache;
  • watering mouth;
  • sweating;
  • increased urination;
  • nausea, vomiting, or diarrhea; or
  • dizziness.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about carbachol ophthalmic (Miostat)?

Contact your doctor immediately if you notice any decrease in vision or an increase in "floaters" in your visual field. Rarely, carbachol ophthalmic may cause retinal detachment. Retinal detachment can lead to blind spots, floaters in your visual field, and even blindness. Your doctor will want to check your retina before you use this medicine to determine if you have an increased risk of retinal detachment.

Do not touch the dropper to any surface, including the eyes or hands. The dropper is sterile. If it becomes contaminated, it could cause an infection in the eye.

Apply light pressure to the inside corner of the eye (near the nose) after each drop to prevent the fluid from draining down the tear duct.

Use caution when driving, operating machinery, or performing other hazardous activities. Carbachol ophthalmic may cause decreased vision at night. If you experience decreased vision, avoid these activities.

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