Skelaxin

DRUG DESCRIPTION

SKELAXIN® (metaxalone) is available as an 800 mg oval, scored pink tablet.

Chemically, metaxalone is 5-[(3,5- dimethylphenoxy) methyl]-2-oxazolidinone. The empirical formula is C12H15N03, which corresponds to a molecular weight of 221.25. The structural formula is:

SKELAXIN (metaxalone) structural formula illustration

Metaxalone is a white to almost white, odorless crystalline powder freely soluble in chloroform, soluble in methanol and in 96% ethanol, but practically insoluble in ether or water. Each tablet contains 800 mg metaxalone and the following inactive ingredients: alginic acid, ammonium calcium alginate, B-Rose Liquid, corn starch, and magnesium stearate.

What are the possible side effects of metaxalone (Skelaxin)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using metaxalone and call your doctor at once if you have any of these serious side effects:

  • nausea, stomach pain, loss of appetite;
  • low fever;
  • dark urine, clay-colored stools; or
  • jaundice (yellowing of the skin or eyes).

Less serious side effects may include:

  • drowsiness, dizziness;
  • ...

Read All Potential Side Effects and See Pictures of Skelaxin »

What are the precautions when taking metaxalone (Skelaxin)?

Before taking metaxalone, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: severe liver disease, severe kidney disease, history of low blood cell counts (e.g., hemolytic anemia, other anemias) due to a drug reaction.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, seizures.

This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that...

Read All Potential Precautions of Skelaxin »


Skelaxin Consumer (continued)

SIDE EFFECTS: Stomach upset, nausea, constipation, dry mouth, headache, blurred vision, lightheadedness, dizziness or drowsiness may occur during the first few days as your body adjusts to this medication. If these symptoms persist or worsen, notify your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately if any of these unlikely but serious side effects occur: mental/mood changes, signs of infection (e.g., persistent sore throat, fever), yellowing eyes or skin, unusual tiredness, fast/pounding heartbeat, worsening of seizures.

A serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS: Before taking metaxalone, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: severe liver disease, severe kidney disease, history of low blood cell counts (e.g., hemolytic anemia, other anemias) due to a drug reaction.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, seizures.

This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.

To minimize dizziness and lightheadedness, get up slowly when rising from a seated or lying position.

Caution is advised when using this drug in the elderly because they may be more sensitive to its side effects, especially dizziness and drowsiness.

This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor.

It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.


Skelaxin Patient Information Including Side Effects

Brand Names: Skelaxin

Generic Name: metaxalone (Pronunciation: me TAX a lone)

  • What is metaxalone (Skelaxin)?
  • What are the possible side effects of metaxalone (Skelaxin)?
  • What is the most important information I should know about metaxalone (Skelaxin)?
  • What should I discuss with my healthcare provider before taking metaxalone (Skelaxin)?
  • How should I take metaxalone (Skelaxin)?
  • What happens if I miss a dose (Skelaxin)?
  • What happens if I overdose (Skelaxin)?
  • What should I avoid while taking metaxalone (Skelaxin)?
  • What other drugs will affect metaxalone (Skelaxin)?
  • Where can I get more information?

What is metaxalone (Skelaxin)?

Metaxalone is a muscle relaxant. It works by blocking nerve impulses (or pain sensations) in the brain.

Metaxalone is used together with rest and physical therapy to treat skeletal muscle conditions such as pain or injury.

Metaxalone may also be used for other purposes not listed in this medication guide.

What are the possible side effects of metaxalone (Skelaxin)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using metaxalone and call your doctor at once if you have any of these serious side effects:

  • nausea, stomach pain, loss of appetite;
  • low fever;
  • dark urine, clay-colored stools; or
  • jaundice (yellowing of the skin or eyes).

Less serious side effects may include:

  • drowsiness, dizziness;
  • feeling nervous or irritable;
  • headache;
  • mild nausea, vomiting, upset stomach; or
  • skin rash.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about metaxalone (Skelaxin)?

Do not use this medication if you are allergic to metaxalone, or if you have anemia (a lack of red blood cells), or severe kidney or liver disease.

Before using metaxalone, tell your doctor if you are allergic to any drugs, or if you have liver or kidney disease. You may need a dose adjustment or special tests to safely take metaxalone.

Metaxalone can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid drinking alcohol. It can increase some of the side effects of metaxalone.

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