Methylene Blue

DRUG DESCRIPTION

Methylene Blue (methylene blue injection) Injection, USP is a sterile solution of methylene blue (methylene blue injection) in water for injection suitable for parenteral administration.

Methylene Blue structural formula illustration

C16H18ClN3S MW = 319.86

Each mL of solution contains 10 mg of methylene blue (methylene blue injection) .

What are the possible side effects of methylene blue (Urolene Blue)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

  • severe nausea, vomiting, or stomach pain;
  • pain in your chest or behind your breast bone;
  • pale or blue skin;
  • high fever, fast or pounding heartbeats, trouble breathing; or
  • confusion, feeling like you might pass out.

Less serious...

Read All Potential Side Effects and See Pictures of Methylene Blue

What are the precautions when taking methylene blue injection (Methylene Blue)?

Consult your...

Read All Potential Precautions of Methylene Blue


Methylene Blue Consumer (continued)

SIDE EFFECTS: Consult your pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS: Consult your pharmacist.


Methylene Blue Patient Information Including Side Effects

Brand Names: Urolene Blue

Generic Name: methylene blue (oral and injection) (Pronunciation: METH i leen BLOO)

  • What is methylene blue (Methylene Blue)?
  • What are the possible side effects of methylene blue (Methylene Blue)?
  • What is the most important information I should know about methylene blue (Methylene Blue)?
  • What should I discuss with my health care provider before taking methylene blue (Methylene Blue)?
  • How should I take methylene blue (Methylene Blue)?
  • What happens if I miss a dose (Methylene Blue)?
  • What happens if I overdose (Methylene Blue)?
  • What should I avoid while taking methylene blue (Methylene Blue)?
  • What other drugs will affect methylene blue (Methylene Blue)?
  • Where can I get more information?

What is methylene blue (Methylene Blue)?

Methemoglobin is a form of hemoglobin (HEEM o glo bin). Hemoglobin is a substance in blood that carries oxygen and distributes it to your tissues and organs. However, methemoglobin is not a type of hemoglobin that is useful in carrying oxygen.

Methemoglobin normally exists in small amounts in the blood. However, when methemoglobin levels increase, the blood is less efficient in circulating oxygen. The resulting lack of oxygen throughout the body can cause symptoms such as pale or blue-colored skin.

Methemoglobinemia is a condition in which methemoglobin is present in high levels in the blood. Methemoglobinemia usually occurs when a person is exposed to certain drugs or chemicals such as nitrites. It may also be caused by a genetic disorder.

Methylene blue injection is used to treat methemoglobinemia. It works by converting methemoglobin to a more efficient type of hemoglobin to better carry oxygen throughout the body.

Methylene blue oral is used to treat methemoglobinemia and urinary tract infections. It works as a mild antiseptic to kill bacteria in the urinary tract. You will most likely also be given an antibiotic medication to treat your infection.

Methylene blue is also used as a dye or staining agent to make certain body fluids and tissues easier to view during surgery or on an x-ray or other diagnostic exam.

Methylene blue may also be used for other purposes not listed in this medication guide.

What are the possible side effects of methylene blue (Methylene Blue)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

  • severe nausea, vomiting, or stomach pain;
  • pain in your chest or behind your breast bone;
  • pale or blue skin;
  • high fever, fast or pounding heartbeats, trouble breathing; or
  • confusion, feeling like you might pass out.

Less serious side effects may include:

  • mild bladder irritation;
  • mild nausea, vomiting, diarrhea, upset stomach;
  • dizziness;
  • headache; or
  • increased sweating.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about methylene blue (Methylene Blue)?

You should not use this medication if you are allergic to methylene blue, or if you have severe kidney problems.

Before using methylene blue, tell your doctor if you have kidney disease, or glucose-6-phosphate dehydrogenase (G6PD) deficiency.

Also tell your doctor about all other medications you use, especially antacids, diuretics (water pills), sodium bicarbonate, or acetazolamide (Diamox).

Methylene blue will most likely cause your urine or stools to appear blue or green in color. This is a normal side effect of the medication and will not cause any harm.

This medication can cause you to have unusual results with certain medical tests. Tell any doctor who treats you that you are using methylene blue.

Call your doctor at once if you have a serious side effect such as severe vomiting or stomach pain, pain in your chest or behind your breast bone, pale or blue skin, high fever, fast or pounding heartbeats, trouble breathing, confusion, or feeling like you might pass out.

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