CANTIL tablets for oral administration contain 25 mg mepenzolate bromide USP. The anticholinergic agent mepenzolate bromide USP chemically is 3-[(hydroxydiphenylacetyl)oxy]-1,1-dimethylpiperidinium bromide and has the following structure:

Mepenzolate bromide occurs as a white or light cream-colored powder, which is freely soluble in methanol, slightly soluble in water and chloroform, and practically insoluble in ether. Each yellow tablet contains 25 mg mepenzolate bromide USP. This tablet also contains inactive ingredients: confectioners' sugar, corn starch, corn syrup solids, FD&C Yellow No. 5 (tartrazine), (see PRECAUTIONS, General), lactose, magnesium stearate and microcrystalline cellulose.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately if any of these unlikely but serious side effects occur: mental/mood changes, eye pain/pressure, fast/pounding heartbeat, difficulty urinating, decreased sexual ability.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS: Before taking mepenzolate, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: glaucoma, myasthenia gravis, movement/blockage disorders of the stomach/bowels (e.g., paralytic ileus, pyloroduodenal stenosis, achalasia, intestinal atony), difficulty urinating (e.g., prostatic hypertrophy), a certain bowel disorder (toxic megacolon).

Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, kidney disease, heart/blood vessel disease (e.g., congestive heart failure, coronary artery disease, tachycardia), high blood pressure, overactive thyroid (hyperthyroidism), esophagus problems (e.g., GERD), nerve disorders (e.g., autonomic neuropathy), diarrhea, breathing problems (e.g., asthma), a certain bowel disease (ulcerative colitis).

Before having surgery, tell your doctor or dentist that you are using this medication.

This drug may make you dizzy or drowsy or cause blurred vision. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely. Limit alcoholic beverages.

This medication can decrease sweating. To prevent heatstroke, avoid becoming overheated in hot weather, in saunas, and during exercise/other strenuous activities.

Caution is advised when using this drug in the elderly because they may be more sensitive to the side effects.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.