Minoxidil

DRUG DESCRIPTION

Minoxidil tablets contain minoxidil (minoxidil (minoxidil (minoxidil tablets) tablets) tablets) , an antihypertensive peripheral vasodilator. Minoxidil (minoxidil (minoxidil (minoxidil tablets) tablets) tablets) occurs as a white to off-white, crystalline powder, soluble in alcohol and propylene glycol; sparingly soluble in methanol; slightly soluble in water; practically insoluble in chloroform, acetone and ethyl acetate. The chemical name for minoxidil (minoxidil (minoxidil (minoxidil tablets) tablets) tablets) is 2,4-Pyrimidinediamine, 6-(1-piperidinyl)-, 3-oxide. The structural formula is represented below:

Minoxidil  Structural Formula Illustration

C9H15N5O........M.W. 209.25

Minoxidil (minoxidil (minoxidil (minoxidil tablets) tablets) tablets) tablets for oral administration contain either 2.5 mg or 10 mg of minoxidil.

Minoxidil (minoxidil (minoxidil (minoxidil tablets) tablets) tablets) Tablets USP 2.5 mg and 10 mg contain the following inactive ingredients: anhydrous lactose, docusate sodium, magnesium stearate, microcrystalline cellulose, sodium benzoate and sodium starch glycolate.

What are the possible side effects of minoxidil (Loniten)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

  • dry cough, sharp or stabbing chest pain;
  • chest pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;
  • trouble breathing (especially while lying down);
  • swelling in your legs, ankles, or feet;
  • rapid weight gain of 5 pounds or...

Read All Potential Side Effects and See Pictures of Minoxidil

What are the precautions when taking minoxidil tablets (Minoxidil)?

Before taking minoxidil, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: recent heart attack (within the last month), certain type of tumor (pheochromocytoma).

Before using this medication, tell your doctor or pharmacist your medical history, especially of: certain lung problem (pulmonary hypertension), heart problems (e.g., chest pain, heart failure), kidney disease, liver disease, stroke.

This drug may make you dizzy or drowsy. Do...

Read All Potential Precautions of Minoxidil


Minoxidil Consumer (continued)

SIDE EFFECTS: Dizziness, drowsiness, and tiredness may occur while taking this medication, especially during the first few weeks as your body adjusts to the lower blood pressure. This is normal. Continue taking the medication as directed. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately if any of these unlikely but serious side effects occur: abdominal pain/swelling, easy bleeding/bruising, difficulty breathing (especially when lying down), dry cough, fainting, fast/irregular heartbeat, signs of severe infection (e.g., fever, persistent sore throat), swelling of the hands/ankles/feet, weight gain of more than 5 pounds.

Minoxidil may cause increased growth or darkening of fine body hairs. If this is bothersome, consult your doctor. When you stop taking the medication, the hair will usually return to normal within 1 to 6 months.

Seek immediate medical attention if any of these rare but very serious side effects occur: chest/jaw/left arm pain, confusion, severe heartburn, hearing/vision loss, slurred speech, weakness on one side of the body.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS: Before taking minoxidil, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: recent heart attack (within the last month), certain type of tumor (pheochromocytoma).

Before using this medication, tell your doctor or pharmacist your medical history, especially of: certain lung problem (pulmonary hypertension), heart problems (e.g., chest pain, heart failure), kidney disease, liver disease, stroke.

This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Avoid alcoholic beverages.

Before having surgery, tell your doctor or dentist that you are taking this medication.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

This drug passes into breast milk but is unlikely to have undesirable effects on a nursing infant. Consult your doctor before breast-feeding.


Minoxidil Patient Information Including Side Effects

Brand Names: Loniten

Generic Name: minoxidil (Pronunciation: min OX i dil)

  • What is minoxidil (Minoxidil)?
  • What are the possible side effects of minoxidil (Minoxidil)?
  • What is the most important information I should know about minoxidil (Minoxidil)?
  • What should I discuss with my healthcare provider before taking minoxidil (Minoxidil)?
  • How should I take minoxidil (Minoxidil)?
  • What happens if I miss a dose (Minoxidil)?
  • What happens if I overdose (Minoxidil)?
  • What should I avoid while taking minoxidil (Minoxidil)?
  • What other drugs will affect minoxidil (Minoxidil)?
  • Where can I get more information?

What is minoxidil (Minoxidil)?

Minoxidil is a vasodilator that relaxes (widens) blood vessels and improves blood flow.

Minoxidil is used to treat high blood pressure (hypertension). It is usually given together with two other medications including a diuretic (water pill).

Minoxidil may also be used for other purposes not listed in this medication guide.

What are the possible side effects of minoxidil (Minoxidil)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

  • dry cough, sharp or stabbing chest pain;
  • chest pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;
  • trouble breathing (especially while lying down);
  • swelling in your legs, ankles, or feet;
  • rapid weight gain of 5 pounds or more;
  • fast or pounding heartbeats;
  • sudden numbness, weakness, headache, confusion, or problems with vision, speech, or balance;
  • fever, sore throat, and headache with a severe blistering, peeling, and red skin rash;
  • the first sign of any skin rash, no matter how mild;
  • easy bruising or bleeding; or
  • feeling like you might pass out.

Less serious side effects may include:

  • nausea, vomiting;
  • breast pain or tenderness; or
  • changes in the color, length, or thickness of body or facial hair.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about minoxidil (Minoxidil)?

Minoxidil tablets should not be used to promote scalp hair growth.

You should not use this medication if you are allergic to minoxidil, or if you have pheochromocytoma (adrenal gland tumor).

Before using minoxidil, tell your doctor if you have angina (chest pain), congestive heart failure, kidney disease, epilepsy or other seizure disorder, or if you have recently had a heart attack.

Tell your doctor about all other medications you use, especially guanethidine (Ismelin).

Call your doctor at once if you have a serious side effect such as swelling in your legs or ankles, chest pain, fast or pounding heartbeats, trouble breathing, swelling or rapid weight gain, sudden numbness or problems with vision or speech, the first sign of any skin rash, or if you feel like you might pass out.

Keep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms, so you may not know when your blood pressure is high. You may need to use blood pressure medication for the rest of your life.

You may need to receive your first few doses of minoxidil in a hospital setting where your heart and blood pressure can be monitored in case the medication causes serious side effects.

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