Sansert

(Generic versions may still be available.)

DRUG DESCRIPTION

Sansert® (methysergide maleate) is a partially synthetic compound structurally related to lysergic acid butanolamide, well-known as methylergonovine in obstetrical practice as an oxytocic agent. Chemically, methysergide maleate is designated as ergoline-8-carboxamide, 9,10-didehydro-N-[1-(hydroxymethyl)propyl]-1,6-dimethyl-, (8?)-, (Z)-2-butenedioate (1:1) (salt). The chemical structure is:

Methylation in the number 1 position of the ring structure enormously enhances the antagonism to serotonin which is present to a much lesser degree in the partially methylated compound (methylergonovine maleate) as well as profoundly altering other pharmacologic properties.

Active Ingredient: methysergide maleate, USP.

Inactive Ingredients: acacia, carnauba wax, colloidal silicon dioxide, FD&C Blue #1, FD&C Yellow #5, gelatin, lactose, malic acid, povidone, sodium benzoate, starch (corn), stearic acid, sucrose, synthetic black iron oxide, talc, and titanium dioxide.

What are the possible side effects of methysergide (Sansert)?

Stop taking methysergide and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives).

Notify your doctor immediately if you experience leg cramps when walking; hip, side, or chest pain; painful urination; shortness of breath; or coldness, numbness, or pain in your hands, feet, arms, or legs.

Other, less serious side effects may be more likely to occur. Continue to take methysergide and talk to your doctor if you...

Read All Potential Side Effects and See Pictures of Sansert »


Sansert Patient Information Including Side Effects

Brand Names: Sansert

Generic Name: methysergide (Pronunciation: meth i SER jide)

  • What is methysergide (Sansert)?
  • What are the possible side effects of methysergide (Sansert)?
  • What is the most important information I should know about methysergide (Sansert)?
  • What should I discuss with my healthcare provider before taking methysergide (Sansert)?
  • How should I take methysergide (Sansert)?
  • What happens if I miss a dose (Sansert)?
  • What happens if I overdose (Sansert)?
  • What should I avoid while taking methysergide (Sansert)?
  • What other drugs will affect methysergide (Sansert)?
  • Where can I get more information?

What is methysergide (Sansert)?

The exact way that methysergide works is unknown. It is believed to be involved in narrowing the veins and arteries that supply blood to your head.

Methysergide is used to prevent vascular headaches (e.g., migraines) and to reduce their severity.

Methysergide may also be used for purposes other than those listed in this medication guide.

What are the possible side effects of methysergide (Sansert)?

Stop taking methysergide and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives).

Notify your doctor immediately if you experience leg cramps when walking; hip, side, or chest pain; painful urination; shortness of breath; or coldness, numbness, or pain in your hands, feet, arms, or legs.

Other, less serious side effects may be more likely to occur. Continue to take methysergide and talk to your doctor if you experience

  • nausea, vomiting, heartburn, or abdominal pain;
  • diarrhea or constipation;
  • drowsiness, dizziness, or lightheadedness;
  • weakness or poor coordination;
  • insomnia;
  • a rash or facial flushing;
  • weight gain; or
  • muscle or joint aches or discomfort.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What is the most important information I should know about methysergide (Sansert)?

Notify your doctor immediately if you experience leg cramps when walking; hip, side, or chest pain; painful urination; shortness of breath; or coldness, numbness, or pain in your hands, feet, arms, or legs.

Use caution when driving, operating machinery, or performing other hazardous activities. Methysergide may cause drowsiness. If you experience drowsiness, avoid these activities.

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