Metvixia

DRUG DESCRIPTION

Metvixia (methyl aminolevulinate cream) Cream is an oil in water emulsion. Metvixia (methyl aminolevulinate cream) Cream contains methyl aminolevulinate hydrochloride equivalent to168 mg/g of methyl aminolevulinate. Methyl aminolevulinate hydrochloride is a white to slightly yellow powder that is freely soluble in water and methanol, soluble in ethanol and practically insoluble in most organic solvents.

The chemical formula for methyl aminolevulinate HCl is C6H11NO3.HCl (MW=181.62) and it has the following structural formula:

METVIXIA® (methyl aminolevulinate) Structural Formula Illustration

Metvixia (methyl aminolevulinate cream) Cream, for topical use only, is cream to pale yellow in color, contains glyceryl monostearate, cetostearyl alcohol, polyoxyl stearate, cholesterol and oleyl alcohol as emulsifying agents. It also contains glycerin, white petrolatum, isopropyl myristate, refined peanut oil, refined almond oil as emollients, edetate disodium as a chelating agent and methylparaben and propylparaben as preservatives.

What are the possible side effects of methyl aminolevulinate (Metvixia)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have severe stinging, burning, redness, oozing, or swelling of treated skin areas, especially if you have these effects for longer than 3 weeks after treatment.

Less serious side effects may include:

  • mild skin redness, warmth, burning, or swelling;
  • puffy eyes;
  • slight pain; or
  • ...

Read All Potential Side Effects and See Pictures of Metvixia »


Metvixia Patient Information Including Side Effects

Brand Names: Metvixia

Generic Name: methyl aminolevulinate (topical) (Pronunciation: METH il a MEE noe LEV ue LIN ate)

  • What is methyl aminolevulinate (Metvixia)?
  • What are the possible side effects of methyl aminolevulinate (Metvixia)?
  • What is the most important information I should know about methyl aminolevulinate (Metvixia)?
  • What should I discuss with my health care provider before taking methyl aminolevulinate (Metvixia)?
  • How is methyl aminolevulinate used (Metvixia)?
  • What happens if I miss a dose (Metvixia)?
  • What happens if I overdose (Metvixia)?
  • What should I avoid while taking methyl aminolevulinate (Metvixia)?
  • What other drugs will affect methyl aminolevulinate (Metvixia)?
  • Where can I get more information?

What is methyl aminolevulinate (Metvixia)?

Methyl aminolevulinate makes your skin more sensitive to light. It works by causing a reaction with light that can destroy certain types of diseased skin cells.

Methyl aminolevulinate topical (for the skin) is used in combination with red light therapy to treat a skin condition called actinic keratosis of the face and scalp.

Methyl aminolevulinate may also be used for other purposes not listed in this medication guide.

What are the possible side effects of methyl aminolevulinate (Metvixia)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have severe stinging, burning, redness, oozing, or swelling of treated skin areas, especially if you have these effects for longer than 3 weeks after treatment.

Less serious side effects may include:

  • mild skin redness, warmth, burning, or swelling;
  • puffy eyes;
  • slight pain; or
  • itching, peeling, scabs or crusting of treated skin.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.

What is the most important information I should know about methyl aminolevulinate (Metvixia)?

You should not use this medication if you are allergic to methyl aminolevulinate, porphyrins, peanuts or almonds, or if your skin is especially sensitive to light.

Before you are treated with methyl aminolevulinate, tell your doctor about all of your medical conditions. Also tell your doctor about all other medications you use, especially drugs that can make your skin more sensitive to sunlight, such as certain antibiotics, heart or blood pressure medications, diuretics (water pills), sulfa drugs, oral diabetes medications, or NSAID pain or arthritis medicines.

Methyl aminolevulinate is applied by a healthcare provider in a clinic setting.

For at least 48 hours after your treatment, avoid exposing treated skin to sunlight, sunlamps, tanning beds, or other bright lights. Sunscreen is not effective enough to protect treated skin from harm caused by bring light during this time. Wear protective clothing whenever you are outdoors.

Call your doctor at once if you have severe stinging, burning, redness, oozing, or swelling of treated skin areas, especially if you have these effects for longer than 3 weeks after treatment.

It may take several weeks before you notice improvement in your skin condition. Your doctor will need to check your treated skin 3 months after the end of your last treatment with methyl aminolevulinate.

Your skin lesions may need to be treated more than once, and they may come back after treatment. Talk to your doctor about the number of treatments needed to treat your condition.

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