Nitropress

DRUG DESCRIPTION

Sodium nitroprusside is disodium pentacyanonitrosylferrate(2-) dihydrate, an inorganic hypotensive agent whose structural formula is

NITROPRESS (sodium nitroprusside) Structural Formula Illustration

whose molecular formula is Na2[Fe(CN)5NO] 2H2O, and whose molecular weight is 297.95. Dry sodium nitroprusside is a reddish-brown powder, soluble in water. In an aqueous solution infused intravenously, sodium nitroprusside is a rapid-acting vasodilator, active on both arteries and veins.

Sodium nitroprusside solution is rapidly degraded by trace contaminants, often with resulting color changes. (See DOSAGE AND ADMINISTRATION section.) The solution is also sensitive to certain wavelengths of light, and it must be protected from light in clinical use.

NITROPRESS (Sodium Nitroprusside Injection) is available as:

50 mg Fliptop Vial - Each 2 mL vial contains the equivalent of 50 mg sodium nitroprusside dihydrate in sterile water for injection.

What are the possible side effects of nitroprusside (Nitropress)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Tell your caregivers at once if you have any of these serious side effects:

  • feeling extremely light-headed, even while lying down;
  • confusion, ringing in your ears;
  • fainting, breathing that stops;
  • gasping or struggling to breathe;
  • dizziness with nausea and vomiting, confusion, rapid breathing, and seizure;
  • ...

Read All Potential Side Effects and See Pictures of Nitropress


Nitropress Patient Information Including Side Effects

Brand Names: Nitropress

Generic Name: nitroprusside (Pronunciation: nye troe PRUS ide)

  • What is nitroprusside (Nitropress)?
  • What are the possible side effects of nitroprusside (Nitropress)?
  • What is the most important information I should know about nitroprusside (Nitropress)?
  • What should I discuss with my health care provider before receiving nitroprusside (Nitropress)?
  • How should I take nitroprusside (Nitropress)?
  • What happens if I miss a dose (Nitropress)?
  • What happens if I overdose (Nitropress)?
  • What should I avoid while receiving nitroprusside (Nitropress)?
  • What other drugs will affect nitroprusside (Nitropress)?
  • Where can I get more information?

What is nitroprusside (Nitropress)?

Nitroprusside is a vasodilator that works by relaxing the muscles in your blood vessels to help them dilate (widen). This lowers blood pressure and allows blood to flow more easily through your veins and arteries.

Nitroprusside is used to treat congestive heart failure and life-threatening high blood pressure (hypertension). Nitroprusside is also used to keep blood pressure low during a surgery.

Nitroprusside may also be used for purposes other than those listed in this medication guide.

What are the possible side effects of nitroprusside (Nitropress)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Tell your caregivers at once if you have any of these serious side effects:

  • feeling extremely light-headed, even while lying down;
  • confusion, ringing in your ears;
  • fainting, breathing that stops;
  • gasping or struggling to breathe;
  • dizziness with nausea and vomiting, confusion, rapid breathing, and seizure;
  • tremors, chills, bowel or bladder urgency;
  • fast, slow, or uneven heart rate;
  • easy bruising or bleeding; or
  • muscle pain or weakness, numb or cold feeling in your arms and legs.

Less serious side effects may be more likely to occur, such as:

  • skin rash;
  • warmth, redness, or tingly feeling under your skin;
  • darkening or deeper color of veins through your skin; or
  • pain or irritation where the needle is placed.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about nitroprusside (Nitropress)?

You should not receive this medication if you are allergic to nitroprusside, or if you have hereditary vision loss (Leber's disease), vision problems caused by smoking, or a history of blood clot in your brain.

Before receiving nitroprusside, tell your doctor if you have high blood pressure (hypertension), liver disease, anemia (a lack of red blood cells), a seizure disorder, or a history of head injury or brain tumor.

Seek emergency medical attention if you think you have received too much of this medicine.

Symptoms of a nitroprusside overdose may include nausea, vomiting, stomach pain, sweating, severe dizziness, headache, muscle twitching, fast or pounding heartbeat, restless feeling, and chest or back pain.

Tell your caregivers right away about any serious side effects such as breathing problems, tremors or chills, numbness or cold feeling in your hands or feet, easy bruising, unusual bleeding, muscle pain or weakness, confusion, feeling extremely light-headed, or fainting.

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