Nimotop

DRUG DESCRIPTION

Nimotop® (nimodipine) belongs to the class of pharmacological agents known as calcium channel blockers. Nimodipine is isopropyl 2 - methoxyethyl 1, 4 - dihydro - 2, 6 - dimethyl - 4 - (m-nitrophenyl) - 3, 5 - pyridinedicarboxylate. It has a molecular weight of 418.5 and a molecular formula of C21H26N2O7. The structural formula is:

NIMOTOP® (nimodipine) Structural Formula Illustration

Nimodipine is a yellow crystalline substance, practically insoluble in water.

NIMOTOP® (nimodipine) capsules are formulated as soft gelatin capsules for oral administration. Each liquid filled capsule contains 30 mg of nimodipine in a vehicle of glycerin, peppermint oil, purified water and polyethylene glycol 400. The soft gelatin capsule shell contains gelatin, glycerin, purified water and titanium dioxide.

What are the possible side effects of nimodipine (Nimotop)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using nimodipine and call your doctor at once if you have any of these serious side effects:

  • unusually fast or slow heartbeats;
  • fainting or severe dizziness;
  • easy bruising or bleeding, unusual weakness;
  • swelling in your legs or ankles.

Other, less serious side effects may be more likely. Continue taking nimodipine...

Read All Potential Side Effects and See Pictures of Nimotop »

What are the precautions when taking nimodipine (Nimotop)?

Before taking nimodipine, tell your doctor or pharmacist if you are allergic to it; or to other dihydropyridine calcium channel blockers (such as amlodipine, nifedipine); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: chest pain/recent heart attack, low blood pressure, recent head injury, liver disease.

This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.

Before having surgery, tell your doctor or dentist...

Read All Potential Precautions of Nimotop »


Nimotop Consumer (continued)

SIDE EFFECTS: Dizziness, lightheadedness, flushing, or swelling ankles/feet may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

To reduce dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately if any of these unlikely but serious side effects occur: fainting, slow/fast heartbeat.

Tell your doctor immediately if any of these rare but very serious side effects occur: severe abdominal pain, stomach bloating, inability to have a bowel movement for more than 3 days, severe nausea/vomiting, vision changes.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS: Before taking nimodipine, tell your doctor or pharmacist if you are allergic to it; or to other dihydropyridine calcium channel blockers (such as amlodipine, nifedipine); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: chest pain/recent heart attack, low blood pressure, recent head injury, liver disease.

This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.

Before having surgery, tell your doctor or dentist that you are taking this medication.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is not known if this medication passes into breast milk. Consult your doctor before breast-feeding.


Nimotop Patient Information Including Side Effects

Brand Names: Nimotop

Generic Name: nimodipine (Pronunciation: nih MO dih peen)

  • What is nimodipine (Nimotop)?
  • What are the possible side effects of nimodipine (Nimotop)?
  • What is the most important information I should know about nimodipine (Nimotop)?
  • What should I discuss with my healthcare provider before taking nimodipine (Nimotop)?
  • How should I take nimodipine (Nimotop)?
  • What happens if I miss a dose (Nimotop)?
  • What happens if I overdose (Nimotop)?
  • What should I avoid while taking nimodipine (Nimotop)?
  • What other drugs will affect nimodipine (Nimotop)?
  • Where can I get more information?

What is nimodipine (Nimotop)?

Nimodipine is in a group of drugs called calcium channel blockers. Nimodipine relaxes (widens) blood vessels and improves blood flow.

Nimodipine is used to prevent brain damage caused by reduced blood flow to the brain resulting from aneurysm (AN-yor-iz-m), a dilated or ruptured blood vessel in the brain.

Nimodipine may also be used for purposes other than those listed here.

What are the possible side effects of nimodipine (Nimotop)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using nimodipine and call your doctor at once if you have any of these serious side effects:

  • unusually fast or slow heartbeats;
  • fainting or severe dizziness;
  • easy bruising or bleeding, unusual weakness;
  • swelling in your legs or ankles.

Other, less serious side effects may be more likely. Continue taking nimodipine and talk to your doctor if you have any of these less serious side effects:

  • mild dizziness;
  • flushing (redness, warmth, or tingling feeling);
  • headache;
  • nausea, constipation; or
  • sweating.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about nimodipine (Nimotop)?

Before taking nimodipine, tell your doctor if you have liver disease, low blood pressure, high blood pressure (hypertension) for which you take medicine, or a history of heart problems such as a slow heart rate, congestive heart failure, or heart attack.

Nimodipine gel capsules are to be taken by mouth only. The medicine in the capsule should never be placed into a needle and syringe and injected into a vein. If the person taking nimodipine cannot swallow the capsule, use a needle to make a hole in each end of the capsule, and squeeze the medicine out into an oral syringe. The syringe can then be used to give the medicine through a nasogastric (through the nose and into the stomach) tube.

If you are able to swallow capsules, take nimodipine on an empty stomach, one hour before or two hours after meals.

Avoid drinking alcohol while you are taking nimodipine. Alcohol and nimodipine may cause low blood pressure, drowsiness, or dizziness.

Do not stop taking nimodipine without first talking to your doctor, even if you begin to feel better. If you stop taking the medication, your condition could become worse.

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