Neodecadron

DRUG DESCRIPTION

Ophthalmic Solution NEODECADRON (Neomycin Sulfate-Dexamethasone Sodium Phosphate) is a topical corticosteroid-antibiotic solution for ophthalmic use.

Dexamethasone sodium phosphate is 9-fluoro-11? 17-dihydroxy-16?-methyl-21-(phosphonooxy)pregna-1, 4-diene-3, 20-dione disodium salt. Its empirical formula is C22H28FNa2O8P and its structural formula is:

Dexamethasone sodium phosphate Structural Formula Illustration

Dexamethasone is a synthetic analog of naturally occurring glucocorticoids (hydrocortisone and cortisone).

Dexamethasone sodium phosphate is a water soluble, inorganic ester of dexamethasone. Its molecular weight is 516.41.

Neomycin sulfate, an antibiotic of the aminoglycoside group, is a mixture of the sulfate salts of neomycin, produced by the growth of Streptomyces fradiae Waksman (Fam. Streptomycetaceae). Neomycin is a complex typically containing 8-13% neomycin C, less than 0.2% neomycin A, and the rest, neomycin B. The empirical formula for both neomycin B and neomycin C is C23H46N6O13, and the molecular weight for each is 614.65. Neomycin A (also referred to as neamine) has an empirical formula of C12H26N4O6 and a molecular weight of 322.36. The structural formulae for neomycin sulfate are:

Each milliliter of buffered Ophthalmic Solution NEODECADRON (neomycin and dexamethasone) in the OCUMETER* ophthalmic dispenser contains: dexamethasone sodium phosphate equivalent to 1 mg (0.1%) dexamethasone phosphate, and neomycin sulfate equivalent to 3.5 mg neomycin base. Inactive ingredients: creatinine, sodium citrate, sodium borate, polysorbate 80, disodium edetate, hydrochloric acid to adjust pH to 6.6 -7.2, and water for injection. Benzalkonium chloride 0.02% and sodium bisulfite 0.1% added as preservatives.

What are the possible side effects of neomycin and dexamethasone ophthalmic ()?

Serious side effects are not expected with this medication.

Some burning, stinging, irritation, itching, redness, blurred vision, eyelid itching, eyelid swelling, or sensitivity to light may occur.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at...

Read All Potential Side Effects and See Pictures of Neodecadron


Neodecadron Patient Information Including Side Effects

Brand Names:

Generic Name: neomycin and dexamethasone ophthalmic (Pronunciation: nee oh MYE sin DEX a METH a sone off THAL mik)

  • What is neomycin and dexamethasone ophthalmic ?
  • What are the possible side effects of neomycin and dexamethasone ophthalmic ?
  • What is the most important information I should know about neomycin and dexamethasone ophthalmic ?
  • Who should not use neomycin and dexamethasone ophthalmic ?
  • How should I use neomycin and dexamethasone ophthalmic ?
  • What happens if I miss a dose ?
  • What happens if I overdose ?
  • What should I avoid while using neomycin and dexamethasone ophthalmic ?
  • What other drugs will affect neomycin and dexamethasone ophthalmic ?
  • Where can I get more information?

What is neomycin and dexamethasone ophthalmic ?

Neomycin is an antibiotic. It is used to treat bacterial infections.

Dexamethasone is a steroid. It is used to treat the inflammation associated with bacterial infections of the eye.

Neomycin and dexamethasone ophthalmic is used to treat bacterial infections of the eyes.

Neomycin and dexamethasone ophthalmic may also be used for purposes other than those listed in this medication guide.

What are the possible side effects of neomycin and dexamethasone ophthalmic ?

Serious side effects are not expected with this medication.

Some burning, stinging, irritation, itching, redness, blurred vision, eyelid itching, eyelid swelling, or sensitivity to light may occur.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about neomycin and dexamethasone ophthalmic ?

Contact your doctor if your symptoms begin to get worse or if you do not see any improvement in your condition after a few days.

Do not touch the dropper or tube opening to any surface, including your eyes or hands. The dropper or tube opening is sterile. If it becomes contaminated, it could cause an infection in your eye.

Apply light pressure to the inside corner of your eye (near your nose) after each drop to prevent the fluid from draining down your tear duct.

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