Propine

DRUG DESCRIPTION

PROPINE® contains dipivefrin hydrochloride in a sterile, isotonic solution. Dipivefrin HCI is a white, crystalline powder, freely soluble in water.

Empirical Formula:

C19-H29O5N•HCI

PROPINE® 
  (dipivefrin hydrochloride) Structural Formula Illustration

Chemical Name: (?±) -3,4-Dihydroxy-?-[(methyl-amino) methyl] benzyl-alcohol 3,4-dipivalate hydrochloride.

Contains: Active: dipivefrin HCI 0.1%

Preservative: benzalkonium chloride; Inactives: edetate disodium; sodium chloride; hydrochloric acid to adjust pH; and purified water.

What are the possible side effects of dipivefrin ophthalmic (Propine)?

Stop using dipivefrin and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • severe stinging or burning in your eyes;
  • fast or uneven heart rate; or
  • high blood pressure (severe headache, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath).

Less serious side effects may...

Read All Potential Side Effects and See Pictures of Propine »

What are the precautions when taking dipivefrin (Propine)?

Before using dipivefrin, tell your doctor or pharmacist if you are allergic to it; or to epinephrine; or if you have any other allergies. This product may contain inactive ingredients (such as preservatives like benzalkonium chloride, sulfites found in some brands), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: narrow or closed-angle glaucoma.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: eye problems (e.g., macular edema, lens extraction/aphakia), high blood pressure, heart or blood vessel disease, irregular...

Read All Potential Precautions of Propine »


Propine Consumer (continued)

SIDE EFFECTS: Burning/stinging/irritation/redness of the eye, blurred vision, headache, and increased sensitivity to light may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

Although unlikely, this medication may cause dark staining on your eyes. Tell your doctor promptly if this occurs.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately if any of these unlikely but serious side effects occur: eye pain/swelling, severe headaches, fast/irregular heartbeat.

A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS: Before using dipivefrin, tell your doctor or pharmacist if you are allergic to it; or to epinephrine; or if you have any other allergies. This product may contain inactive ingredients (such as preservatives like benzalkonium chloride, sulfites found in some brands), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: narrow or closed-angle glaucoma.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: eye problems (e.g., macular edema, lens extraction/aphakia), high blood pressure, heart or blood vessel disease, irregular heartbeat.

If you develop an eye infection or injury, or have eye surgery, check with your doctor about whether you should continue to use your current bottle of dipivefrin. You may be advised to start using a new bottle.

Your vision may be temporarily blurred or unstable after applying this drug. Do not drive, use machinery, or do any activity that requires clear vision until you are sure you can perform such activities safely.

This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor.

It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.


Propine Patient Information Including Side Effects

Brand Names: Propine

Generic Name: dipivefrin ophthalmic (Pronunciation: dye pi VEF rin)

  • What is dipivefrin ophthalmic (Propine)?
  • What are the possible side effects of dipivefrin ophthalmic (Propine)?
  • What is the most important information I should know about dipivefrin ophthalmic (Propine)?
  • What should I discuss with my healthcare provider before using dipivefrin ophthalmic (Propine)?
  • How should I use dipivefrin ophthalmic (Propine)?
  • What happens if I miss a dose (Propine)?
  • What happens if I overdose (Propine)?
  • What should I avoid while using dipivefrin ophthalmic (Propine)?
  • What other drugs will affect dipivefrin ophthalmic (Propine)?
  • Where can I get more information?

What is dipivefrin ophthalmic (Propine)?

Dipivefrin reduces the amount of fluid in the eye, which decreases pressure inside the eye.

Dipivefrin ophthalmic is used to treat open-angle glaucoma or ocular hypertension (high pressure inside the eye).

Dipivefrin ophthalmic may also be used for other purposes not listed in this medication guide.

What are the possible side effects of dipivefrin ophthalmic (Propine)?

Stop using dipivefrin and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • severe stinging or burning in your eyes;
  • fast or uneven heart rate; or
  • high blood pressure (severe headache, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath).

Less serious side effects may include:

  • burning, stinging, or itching of your eyes;
  • blurred vision;
  • redness of the eye or eyelid;
  • sensitivity to light;
  • eye pain; or
  • headache.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about dipivefrin ophthalmic (Propine)?

You should not use this medication if you are allergic to dipivefrin, or if you have narrow-angle glaucoma.

Before using dipivefrin, tell your doctor if you are allergic to any drugs, or if you have high blood pressure or a history of cataract surgery.

Do not use this medication while you are wearing contact lenses. This medication may contain a preservative that can be absorbed by soft contact lenses. Wait at least 15 minutes after using dipivefrin before putting your contact lenses in.

Do not allow the dropper tip to touch any surface, including the eyes or hands. If the dropper becomes contaminated it could cause an infection in your eye, which can lead to vision loss or serious damage to the eye.

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