Pfizerpen

DRUG DESCRIPTION

Buffered Pfizerpen (penicillin G potassium) for Injection is a sterile, pyrogen-free powder for reconstitution. Buffered Pfizerpen (penicillin g potassium) for Injection is an antibacterial agent for intramuscular, continuous intravenous drip, intrapleural or other local infusion, and intrathecal administration.

Each million units contains approximately 6.8 milligrams of sodium (0.3 mEq) and 65.6 milligrams of potassium (1.68 mEq).

Chemically, Pfizerpen (penicillin g potassium) is monopotassium 3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo (3.2.0) heptane-2-carboxylate. It has a molecular weight of 372.48 and the following chemical structure:

PFIZERPEN (penicillin G potassium)  Structural Formula Illustration

Formula C16H17KN2O4S

Penicillin G potassium is a colorless or white crystal, or a white crystalline powder which is odorless, or practically so, and moderately hygroscopic. Penicillin G potassium is very soluble in water. The pH of the reconstituted product is between 6.0-8.5.

What are the possible side effects of penicillin G potassium (Pfizerpen)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • swelling, bruising, or irritation where the injection was given;
  • headache with nausea, vomiting, and tiredness;
  • a red, blistering, peeling skin rash;
  • chills, fever, swelling, joint or muscle pain, and confusion;
  • pale skin, easy bruising...

Read All Potential Side Effects and See Pictures of Pfizerpen

What are the precautions when taking penicillin g potassium (Pfizerpen)?

Before using this medication, tell your doctor or pharmacist if you are allergic to it; or to penicillin or cephalosporin antibiotics; or if you have any other allergies. This product may contain inactive ingredients (such as corn for products containing dextrose), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: asthma, kidney disease.

Certain products of this medication contain sodium. Consult your doctor or pharmacist if you are on a salt-restricted diet or if you have a condition that could be worsened by an increase in salt intake (e.g., congestive heart failure).

Certain products of this medication contain potassium....

Read All Potential Precautions of Pfizerpen


Pfizerpen Consumer (continued)

SIDE EFFECTS: If this medication is injected into a muscle, pain at the injection site may occur. If this effect persists or worsens, notify your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: pain/swelling at injection site (if this drug is injected into a vein), joint/muscle pain, muscle weakness, swelling of ankles/feet, dark/cloudy urine, extreme tiredness, fast/slow/irregular heartbeat, new signs of infection (e.g., fever, persistent sore throat), easy bruising/bleeding, change in the amount of urine, numbness/tingling of arms/legs, seizures, uncontrolled movements, confusion.

If used to treat syphilis or other spirochetal infections (e.g., Lyme disease), this medication may cause a condition known as Jarisch-Herxheimer reaction. This condition may occur 1 to 2 hours after you receive the medication and can last up to 24 hours. Notify your doctor immediately if you experience any of these symptoms: fever/chills, muscle pain, worsening of skin sores, fast heartbeat, fast breathing, dizziness, flushing.

This medication may rarely cause a severe intestinal condition (Clostridium difficile-associated diarrhea) due to a type of resistant bacteria. This condition may occur weeks to months after treatment has stopped. Do not use anti-diarrhea products or narcotic pain medications if you have any of these symptoms because these products may make them worse. Tell your doctor immediately if you develop: persistent diarrhea, abdominal or stomach pain/cramping, blood/mucus in your stool.

Use of this medication for prolonged or repeated periods may result in oral thrush or a new vaginal yeast infection. Contact your doctor if you notice white patches in your mouth, a change in vaginal discharge, or other new symptoms.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS: Before using this medication, tell your doctor or pharmacist if you are allergic to it; or to penicillin or cephalosporin antibiotics; or if you have any other allergies. This product may contain inactive ingredients (such as corn for products containing dextrose), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: asthma, kidney disease.

Certain products of this medication contain sodium. Consult your doctor or pharmacist if you are on a salt-restricted diet or if you have a condition that could be worsened by an increase in salt intake (e.g., congestive heart failure).

Certain products of this medication contain potassium. Consult your doctor or pharmacist if you are taking potassium supplements, salt substitutes containing potassium, or medications that can increase potassium (e.g., ACE inhibitors such as lisinopril), or if you have a high potassium level (hyperkalemia).

Kidney function declines as you grow older. This medication is removed by the kidneys. Therefore, elderly people may be at greater risk for side effects while using this drug.

Kidney function is not fully developed in newborns and infants. This medication is removed by the kidneys. Therefore, newborns and infants may be at greater risk for side effects while using this drug.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

This drug passes into breast milk. Consult your doctor before breast-feeding.


Pfizerpen Patient Information Including Side Effects

Brand Names: Pfizerpen

Generic Name: penicillin G potassium injection (Pronunciation: pen i SILL in G po TASS ee um)

  • What is penicillin G potassium (Pfizerpen)?
  • What are the possible side effects of penicillin G potassium (Pfizerpen)?
  • What is the most important information I should know about penicillin G potassium (Pfizerpen)?
  • What should I discuss with my health care provider before using penicillin G potassium (Pfizerpen)?
  • How should I use penicillin G potassium (Pfizerpen)?
  • What happens if I miss a dose (Pfizerpen)?
  • What happens if I overdose (Pfizerpen)?
  • What should I avoid while taking penicillin G potassium (Pfizerpen)?
  • What other drugs will affect penicillin G potassium (Pfizerpen)?
  • Where can I get more information?

What is penicillin G potassium (Pfizerpen)?

Penicillin G potassium is an antibiotic that fights bacteria in your body.

Penicillin G potassium is used to treat many different types of severe infections, including strep and staph infections, diphtheria, meningitis, gonorrhea, and syphilis.

Penicillin G potassium is also used to prevent infections of the heart valves in people with certain heart conditions who need to have dental work or surgery.

Penicillin G potassium may also be used for other purposes not listed in this medication guide.

What are the possible side effects of penicillin G potassium (Pfizerpen)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • swelling, bruising, or irritation where the injection was given;
  • headache with nausea, vomiting, and tiredness;
  • a red, blistering, peeling skin rash;
  • chills, fever, swelling, joint or muscle pain, and confusion;
  • pale skin, easy bruising or bleeding, unusual weakness;
  • seizure (convulsions); or
  • uneven heartbeats.

Less serious side effects may include:

  • twitching or muscle spasm; or
  • mild skin rash.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about penicillin G potassium (Pfizerpen)?

Do not use this medication if you are allergic to penicillin. Tell your doctor if you have ever had an allergic reaction to a cephalosporin antibiotic such as Ceclor, Ceftin, Duricef, Keflex, Lorabid, Omnicef, Spectracef, and others.

Use this medication for the entire length of time prescribed by your doctor. Your symptoms may get better before the infection is completely treated. Penicillin G potassium will not treat a viral infection such as the common cold or flu.

After you have finished your treatment with penicillin G potassium, your doctor may want to do tests to make sure your infection has completely cleared up.

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