Dibenzyline

DRUG DESCRIPTION

Each Dibenzyline (phenoxybenzamine) capsule, with red cap and body, is imprinted WPC 001 and 10 mg, and contains 10 mg of Phenoxybenzamine Hydrochloride USP. Inactive ingredients consist of D&C Red No. 33, FD&C Red No. 3, FD&C Yellow No. 6, Gelatin NF, Lactose NF, Sodium Lauryl Sulfate NF and Silicon Dioxide NF.

Dibenzyline (phenoxybenzamine) is N-(2-Chloroethyl)-N-(1-methyl-2-phenoxyethyl)benzylamine hydrochloride:

Dibenzyline (phenoxybenzamine hydrochloride) structural formula illustration

Phenoxybenzamine hydrochloride is a colorless, crystalline powder with a molecular weight of 340.3, which melts between 136 and 141C. It is soluble in water, alcohol and chloroform; insoluble in ether.

What are the possible side effects of phenoxybenzamine (Dibenzyline)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using phenoxybenzamine and call your doctor at once if you severe dizziness or if you feel like you might pass out.

Less serious side effects may include:

  • stuffy nose;
  • mild dizziness or drowsiness;
  • blurred vision;
  • trouble having an orgasm;
  • upset stomach; or
  • tired...

Read All Potential Side Effects and See Pictures of Dibenzyline

What are the precautions when taking phenoxybenzamine (Dibenzyline)?

Before taking phenoxybenzamine, tell your doctor or pharmacist if you are allergic to it; or to other alpha blockers (e.g., phentolamine); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: blood vessel disease (e.g., cerebral arteriosclerosis, coronary artery disease), heart disease (e.g., congestive heart failure), kidney disease, lung infections.

Before having surgery, tell your doctor or dentist that you are taking this medication.

This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires...

Read All Potential Precautions of Dibenzyline


Dibenzyline Consumer (continued)

SIDE EFFECTS: Stomach upset, nausea, stuffy nose, drowsiness, dizziness or decrease in pupil size may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

To lower your risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately if any of these unlikely but serious side effects occur: fast heartbeat, fainting, sexual problems in males (e.g., trouble ejaculating), weakness.

For males, in the very unlikely event that you have a painful or prolonged erection lasting 4 or more hours, stop using this drug and seek immediate medical attention, or permanent problems could occur.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any of the following symptoms of a serious allergic reaction: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS: Before taking phenoxybenzamine, tell your doctor or pharmacist if you are allergic to it; or to other alpha blockers (e.g., phentolamine); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: blood vessel disease (e.g., cerebral arteriosclerosis, coronary artery disease), heart disease (e.g., congestive heart failure), kidney disease, lung infections.

Before having surgery, tell your doctor or dentist that you are taking this medication.

This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.

Caution is advised when using this drug in the elderly because they may be more sensitive to its effects, especially dizziness.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding.


Dibenzyline Patient Information Including Side Effects

Brand Names: Dibenzyline

Generic Name: phenoxybenzamine (Pronunciation: fen OX ee BENZ a meen)

  • What is phenoxybenzamine (Dibenzyline)?
  • What are the possible side effects of phenoxybenzamine (Dibenzyline)?
  • What is the most important information I should know about phenoxybenzamine (Dibenzyline)?
  • What should I discuss with my healthcare provider before taking phenoxybenzamine (Dibenzyline)?
  • How should I take phenoxybenzamine (Dibenzyline)?
  • What happens if I miss a dose (Dibenzyline)?
  • What happens if I overdose (Dibenzyline)?
  • What should I avoid while taking phenoxybenzamine (Dibenzyline)?
  • What other drugs will affect phenoxybenzamine (Dibenzyline)?
  • Where can I get more information?

What is phenoxybenzamine (Dibenzyline)?

Phenoxybenzamine lowers blood pressure.

Phenoxybenzamine is used control blood pressure and reduce sweating in people with pheochromocytoma.

Phenoxybenzamine may also be used for other purposes not listed in this medication guide.

What are the possible side effects of phenoxybenzamine (Dibenzyline)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using phenoxybenzamine and call your doctor at once if you severe dizziness or if you feel like you might pass out.

Less serious side effects may include:

  • stuffy nose;
  • mild dizziness or drowsiness;
  • blurred vision;
  • trouble having an orgasm;
  • upset stomach; or
  • tired feeling.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about phenoxybenzamine (Dibenzyline)?

You should not use this medication if you are allergic to phenoxybenzamine.

Before taking phenoxybenzamine, tell your doctor if you have coronary artery disease, a lung infection, or kidney disease.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

Avoid drinking alcohol. It can increase drowsiness caused by phenoxybenzamine.

This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

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