Phentolamine Mesylate for Injection

DRUG DESCRIPTION

Phentolamine Mesylate (phentolamine mesylate) for Injection USP, is an antihypertensive, available in vials for intravenous and intramuscular administration. Each vial contains phentolamine mesylate (phentolamine mesylate) USP, 5 mg and mannitol USP, 25 mg in sterile, lyophilized form.

Phentolamine mesylate is m-[N-(2-Imidazolin-2-ylmethyl)-p-toluidino]phenol monomethanesulfonate (salt), and its structural formula is:

Phentolamine Mesylate Structural Formula Illustration

Molecular Formula - C17H19N3OCH4O3S.............................M.W. - 377.47

Phentolamine mesylate (phentolamine mesylate) USP is a white or off-white, odorless crystalline powder. Its solutions are acid to litmus. It is freely soluble in water and in alcohol, and slightly soluble in chloroform. It melts at about 178C.



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