Robaxin

DRUG DESCRIPTION

robaxin®/robaxin®-750 (methocarbamol tablets, USP), a carbamate derivative of guaifenesin, is a central nervous system (CNS) depressant with sedative and musculoskeletal relaxant properties.

The chemical name of methocarbamol is 3-(2-methoxyphenoxy)-l,2-propanediol 1-carbamate and has the empirical formula C11H15NO5. Its molecular weight is 241.24. The structural formula is shown below.

ROBAXIN - methocarbamol tablet Structural Formula Illustration

Methocarbamol is a white powder, sparingly soluble in water and chloroform, soluble in alcohol (only with heating) and propylene glycol, and insoluble in benzene and n-hexane.

robaxin (methocarbamol) ® is available as a light orange, round, film-coated tablet containing 500 mg of methocarbamol, USP for oral administration. The inactive ingredients present are corn starch, FD&C Yellow 6, hydroxypropyl cellulose, hypromellose, magnesium stearate, polysorbate 20, povidone, propylene glycol, saccharin sodium, sodium lauryl sulfate, sodium starch glycolate, stearic acid, titanium dioxide.

robaxin (methocarbamol) ®-750 is available as an orange capsule-shaped, film-coated tablet containing 750 mg of methocarbamol, USP for oral administration. In addition to the inactive ingredients present in robaxin (methocarbamol) ®, robaxin (methocarbamol) ®-750 also contains D&C Yellow 10.

What are the possible side effects of methocarbamol (Robaxin, Robaxin-750)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using methocarbamol and call your doctor at once if you have any of these serious side effects:

  • slow heart rate;
  • feeling like you might pass out;
  • jaundice (yellowing of your skin or eyes);
  • confusion, spinning sensation, loss of balance; or
  • seizure (convulsions).

Less serious side...

Read All Potential Side Effects and See Pictures of Robaxin »

What are the precautions when taking methocarbamol (Robaxin)?

Before taking methocarbamol, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease, severe difficulty urinating (urinary retention).

This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.

To minimize dizziness and lightheadedness, get up slowly when rising from a seated or lying position.

Caution is advised when...

Read All Potential Precautions of Robaxin »


Robaxin Consumer (continued)

SIDE EFFECTS: Stomach upset, nausea, flushing, constipation, headache, blurred vision, lightheadedness, dizziness or drowsiness may occur during the first few days as your body adjusts to this medication. If these symptoms persist or become severe, notify your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately if any of these unlikely but serious side effects occur: fast/slow heartbeat, fainting, yellowing eyes or skin, persistent nausea/vomiting, stomach/abdominal pain, mental/mood changes, clumsiness, trouble urinating, signs of infection (e.g., persistent sore throat, fever).

This medication may cause your urine to turn green-black in color. This harmless effect is temporary and will disappear when the medication is stopped.

A serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS: Before taking methocarbamol, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease, severe difficulty urinating (urinary retention).

This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.

To minimize dizziness and lightheadedness, get up slowly when rising from a seated or lying position.

Caution is advised when using this drug in the elderly because they may be more sensitive to its side effects, especially dizziness and drowsiness.

This medication should be used during pregnancy only when clearly needed. Discuss the risks and benefits with your doctor.

It is not known if this drug passes into breast milk. Consult your doctor before breast-feeding.


Robaxin Patient Information Including Side Effects

Brand Names: Robaxin, Robaxin-750

Generic Name: methocarbamol (Pronunciation: meth oh KAR ba mal)

  • What is methocarbamol (Robaxin)?
  • What are the possible side effects of methocarbamol (Robaxin)?
  • What is the most important information I should know about methocarbamol (Robaxin)?
  • What should I discuss with my health care provider before taking methocarbamol (Robaxin)?
  • How should I take methocarbamol (Robaxin)?
  • What happens if I miss a dose (Robaxin)?
  • What happens if I overdose (Robaxin)?
  • What should I avoid while taking methocarbamol (Robaxin)?
  • What other drugs will affect methocarbamol (Robaxin)?
  • Where can I get more information?

What is methocarbamol (Robaxin)?

Methocarbamol is a muscle relaxant. It works by blocking nerve impulses (or pain sensations) that are sent to your brain.

Methocarbamol is used together with rest and physical therapy to treat skeletal muscle conditions such as pain or injury.

Methocarbamol may also be used for other purposes not listed in this medication guide.

What are the possible side effects of methocarbamol (Robaxin)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using methocarbamol and call your doctor at once if you have any of these serious side effects:

  • slow heart rate;
  • feeling like you might pass out;
  • jaundice (yellowing of your skin or eyes);
  • confusion, spinning sensation, loss of balance; or
  • seizure (convulsions).

Less serious side effects may include:

  • dizziness, drowsiness;
  • nausea, vomiting;
  • warmth, redness, or tingly feeling under your skin;
  • fever;
  • headache;
  • memory problems;
  • blurred vision;
  • sleep problems (insomnia);
  • stuffy nose; or
  • mild skin rash or itching.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about methocarbamol (Robaxin)?

You should not use this medication if you are allergic to methocarbamol.

Before using methocarbamol, tell your doctor if you are allergic to any drugs, or if you have myasthenia gravis.

You may need to reduce your methocarbamol dose after the first 2 or 3 days of treatment. Follow your doctor's instructions regarding the number of tablets you take each day.

Methocarbamol can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid drinking alcohol while you are taking methocarbamol. It may cause dangerous side effects.

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