Tranxene

DRUG DESCRIPTION

Chemically, TRANXENE (clorazepate dipotassium) is a benzodiazepine. The empirical formula is C16H11ClK2N2O4; the molecular weight is 408.92; 1H-1, 4-Benzodiazepine-3-carboxylic acid, 7-chloro-2,3-dihydro-2-oxo-5-phenyl-, potassium salt compound with potassium hydroxide (1:1) and the structural formula may be represented as follows:

Tranxene T-TAB® (clorazepate dipotassium) Structural Formula Illustration

The compound occurs as a fine, light yellow, practically odorless powder. It is insoluble in the common organic solvents, but very soluble in water. Aqueous solutions are unstable, clear, light yellow, and alkaline.

TRANXENE (clorazepate dipotassium) T-TAB tablets contain either 3.75 mg, 7.5 mg or 15 mg of clorazepate dipotassium for oral administration.

Inactive ingredients for TRANXENE (clorazepate dipotassium) T-TAB Tablets: Colloidal silicon dioxide, FD&C Blue No. 2 (3.75 mg only), FD&C Yellow No. 6 (7.5 mg only), FD&C Red No. 3 (15 mg only), magnesium oxide, magnesium stearate, microcrystalline cellulose, potassium carbonate, potassium chloride, and talc.

What are the possible side effects of clorazepate (Tranxene SD, Tranxene T-Tab)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • confusion, unusual thoughts or behavior;
  • depressed mood, thoughts of suicide or hurting yourself;
  • muscle twitching, tremor; or
  • problems with urination.

Less serious side effects may include:

  • drowsiness,...

Read All Potential Side Effects and See Pictures of Tranxene »

What are the precautions when taking clorazepate dipotassium (Tranxene)?

Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, kidney disease, lung/breathing problems (e.g., COPD, sleep apnea), drug or alcohol abuse.

This drug may make you dizzy or drowsy or cause blurred vision. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely. Avoid alcoholic beverages.

Caution is advised when using this drug in the elderly because they...

Read All Potential Precautions of Tranxene »


Tranxene Consumer (continued)

SIDE EFFECTS: Drowsiness, dizziness, fatigue, dry mouth, upset stomach, constipation, blurred vision, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately if any of these unlikely but serious side effects occur: slurred speech, clumsiness, trouble walking, decreased/increased interest in sex, tremor, trouble urinating, sleep disturbances.

A small number of people who take anticonvulsants for any condition (such as seizure, bipolar disorder, pain) may experience depression, suicidal thoughts/attempts, or other mental/mood problems. Tell your doctor immediately if you or your family/caregiver notice any unusual/sudden changes in your mood, thoughts, or behavior including signs of depression, suicidal thoughts/attempts, thoughts about harming yourself.

Tell your doctor immediately if any of these highly unlikely but very serious side effects occur: stomach/abdominal pain, persistent nausea, vomiting, yellowing eyes or skin, dark urine, persistent sore throat or fever.

A serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS: Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, kidney disease, lung/breathing problems (e.g., COPD, sleep apnea), drug or alcohol abuse.

This drug may make you dizzy or drowsy or cause blurred vision. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely. Avoid alcoholic beverages.

Caution is advised when using this drug in the elderly because they may be more sensitive to the effects of the drug, especially the drowsiness effect.

This medication is not recommended for use during pregnancy due to the potential for harm to an unborn baby. If you become pregnant or think you may be pregnant, inform your doctor immediately. Consult your doctor for more details.

This drug passes into breast milk and may have undesirable effects on a nursing infant. Therefore, breast-feeding while using this medication is not recommended. Consult your doctor before breast-feeding.


Tranxene Patient Information Including Side Effects

Brand Names: Tranxene SD, Tranxene T-Tab

Generic Name: clorazepate (Pronunciation: klor AZ e pate)

  • What is clorazepate (Tranxene)?
  • What are the possible side effects of clorazepate (Tranxene)?
  • What is the most important information I should know about clorazepate (Tranxene)?
  • What should I discuss with my healthcare provider before taking clorazepate (Tranxene)?
  • How should I take clorazepate (Tranxene)?
  • What happens if I miss a dose (Tranxene)?
  • What happens if I overdose (Tranxene)?
  • What should I avoid while taking clorazepate (Tranxene)?
  • What other drugs will affect clorazepate (Tranxene)?
  • Where can I get more information?

What is clorazepate (Tranxene)?

Clorazepate is in a group of drugs called benzodiazepines (ben-zoe-dye-AZE-eh-peens). Clorazepate affects chemicals in the brain that may become unbalanced and cause anxiety or seizures.

Clorazepate is used to treat anxiety disorders, partial seizures, or alcohol withdrawal symptoms.

Clorazepate may also be used for other purposes not listed in this medication guide.

What are the possible side effects of clorazepate (Tranxene)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • confusion, unusual thoughts or behavior;
  • depressed mood, thoughts of suicide or hurting yourself;
  • muscle twitching, tremor; or
  • problems with urination.

Less serious side effects may include:

  • drowsiness, tiredness;
  • amnesia or forgetfulness;
  • dizziness;
  • blurred vision;
  • feeling nervous or irritable;
  • sleep problems (insomnia);
  • muscle weakness, lack of balance or coordination;
  • skin rash;
  • nausea, vomiting, stomach pain, constipation; or
  • dry mouth; or
  • headache.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about clorazepate (Tranxene)?

Do not use this medication if you are allergic to clorazepate or to other benzodiazepines, such as alprazolam (Xanax), chlordiazepoxide (Librium), diazepam (Valium), lorazepam (Ativan), or oxazepam (Serax).

This medication can cause birth defects in an unborn baby. Do not use clorazepate if you are pregnant.

Before taking clorazepate, tell your doctor if you have any breathing problems, glaucoma, kidney or liver disease, or a history of depression, suicidal thoughts, or addiction to drugs or alcohol.

Do not drink alcohol while taking clorazepate. This medication can increase the effects of alcohol.

Avoid using other medicines that make you sleepy. They can add to sleepiness caused by clorazepate.

Clorazepate may be habit-forming and should be used only by the person it was prescribed for. Clorazepate should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it.

Related Drug Centers
  • Tranxene


Related Drugs Index: