Depo-Testosterone

DRUG DESCRIPTION

DEPO-Testosterone Injection, for intramuscular injection, contains testosterone cypionate which is the oil-soluble 17 (beta)- cyclopentylpropionate ester of the androgenic hormone testosterone.

Testosterone cypionate is a white or creamy white crystalline powder, odorless or nearly so and stable in air. It is insoluble in water, freely soluble in alcohol, chloroform, dioxane, ether, and soluble in vegetable oils.

The chemical name for testosterone cypionate is androst-4-en-3-one,17-(3-cyclopentyl-1-oxopropoxy)-, (17?)-. Its molecular formula is C27H40O3, and the molecular weight 412.61.

The structural formula is represented below:

Depo® -Testosterone (testosterone cypionate) structural formula illustration

DEPO-Testosterone (testosterone cypionate injection) Injection is available in two strengths, 100 mg/mL and 200 mg/mL testosterone cypionate.

Each mL of the 100 mg/mL solution contains:

Testosterone cypionate...........................................100 mg
Benzyl benzoate...........................................0.1 mL
Cottonseed oil...........................................736 mg
Benzyl alcohol (as preservative)...........................................9.45 mg

Each mL of the 200 mg/mL solution contains:

Testosterone cypionate...........................................200 mg
Benzyl benzoate...........................................0.2 mL
Cottonseed oil...........................................560 mg
Benzyl alcohol (as preservative) ...........................................9.45 mg

What are the possible side effects of testosterone injection?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • swelling, rapid weight gain;
  • increased or ongoing erection of the penis;
  • bone pain, increased thirst, memory problems, restless feeling, confusion, nausea, loss of appetite, increased urination, weakness, muscle twitching; or
  • nausea, vomiting, stomach pain, loss...

Read All Potential Side Effects and See Pictures of Depo-Testosterone »

What are the precautions when taking testosterone cypionate injection (Depo-Testosterone)?

Before using testosterone, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients (such as sesame oil), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: breast cancer in men, prostate cancer.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: heart disease (such as heart failure, chest pain, heart attack), liver problems, kidney problems, other types of cancer, high cholesterol, high blood pressure, enlarged prostate, sleep apnea, diabetes.

If...

Read All Potential Precautions of Depo-Testosterone »


Depo-Testosterone Consumer (continued)

SIDE EFFECTS: Nausea, vomiting, headache, skin color changes, increased/decreased sexual interest, oily skin, hair loss, and acne may occur. Pain and redness at the injection site may also occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects when it is used at normal doses.

Tell your doctor right away if you have any serious side effects, including: mental/mood changes (such as anxiety, depression, increased anger), trouble sleeping/snoring, signs of serious liver disease (such as persistent abdominal pain/nausea, unusual tiredness, yellowing eyes/skin, dark urine).

If you are male, tell your doctor immediately if any of these unlikely but serious side effects occur: trouble urinating, breast swelling/tenderness, too frequent/prolonged erections.

Rarely, males may have a painful or prolonged erection lasting 4 or more hours. If this occurs, stop using this drug and seek immediate medical attention, or permanent problems could occur.

This medication can decrease sperm production, an effect that may lower male fertility. Consult your doctor for more details.

If you are female, tell your doctor immediately if any of these unlikely but serious side effects occur: deepening of the voice, hoarseness, unusual facial/body hair growth, enlarged clitoris, irregular menstrual periods.

This medication can cause your body to hold on to extra body water (edema). This can increase your risk of heart failure. Tell your doctor immediately if any of these unlikely but serious signs of water retention or heart failure occur: decreased exercise ability, hands/ankles/feet swelling, unusual tiredness, shortness of breath while lying down.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS: Before using testosterone, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients (such as sesame oil), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: breast cancer in men, prostate cancer.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: heart disease (such as heart failure, chest pain, heart attack), liver problems, kidney problems, other types of cancer, high cholesterol, high blood pressure, enlarged prostate, sleep apnea, diabetes.

If you have diabetes, this product may decrease your blood sugar levels. Check your blood sugar levels regularly as directed by your doctor. Tell your doctor immediately if you have symptoms of low blood sugar, such as increased hunger, dizziness, or unusual sweating. Your anti-diabetic medication or diet may need to be adjusted.

This drug may affect your cholesterol and may increase your risk of heart or blood vessel problems (coronary artery disease). Your doctor will monitor your cholesterol level closely.

Tell your doctor if you become bed-ridden (unable to walk) for a prolonged time while using this medication. Your doctor may monitor your blood calcium level to prevent problems.

Caution is advised when using this drug in children because bone growth may be affected, causing shorter adult height. Your child's doctor will monitor growth and bone development during treatment.

This medication must not be used during pregnancy. It may harm an unborn baby. Consult your doctor for more details and to discuss reliable forms of birth control. It is recommended that women using this medication use 2 effective forms of birth control (such as condoms and birth control pills) while using this medication. Consult your doctor.

It is not known whether this drug passes into breast milk. It may affect milk production and it may harm a nursing infant. Breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding.


Depo-Testosterone Patient Information Including Side Effects

Brand Names: Andro LA 200, Delatestryl, Depandro 100, Depo-Testosterone, Testosterone Cypionate, Testosterone Enanthate

Generic Name: testosterone injection (Pronunciation: tes TOS ter one)

  • What is testosterone injection (Depo-Testosterone)?
  • What are the possible side effects of testosterone injection?
  • What is the most important information I should know about testosterone injection?
  • What should I discuss with my healthcare provider before receiving testosterone injection?
  • How is testosterone injection given?
  • What happens if I miss a dose?
  • What happens if I overdose?
  • What should I avoid while receiving testosterone injection?
  • What other drugs will affect testosterone injection?
  • Where can I get more information?

What is testosterone injection (Depo-Testosterone)?

Testosterone is a naturally occurring sex hormone that is produced in a man's testicles. Small amounts of testosterone are also produced in a woman's ovaries and adrenal system.

Testosterone injection is used in men and boys to treat conditions caused by a lack of this hormone, such as delayed puberty, impotence, or other hormonal imbalances. Testosterone injection is also used in women to treat breast cancer that has spread to other parts of the body.

Testosterone injection may also be used for other purposes not listed in this medication guide.

What are the possible side effects of testosterone injection?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • swelling, rapid weight gain;
  • increased or ongoing erection of the penis;
  • bone pain, increased thirst, memory problems, restless feeling, confusion, nausea, loss of appetite, increased urination, weakness, muscle twitching; or
  • nausea, vomiting, stomach pain, loss of appetite, and jaundice (yellowing of the skin or eyes).

Women receiving testosterone injection may develop male characteristics, which could be irreversible if testosterone treatment is continued. Call your doctor as soon as possible if you notice any of these signs of excess testosterone:

  • acne;
  • changes in your menstrual periods;
  • male-pattern hair growth (such as on the chin or chest);
  • male pattern baldness;
  • enlarged clitoris; or
  • increase or decrease in sex drive.

Less serious side effects may include:

  • breast swelling in men;
  • headache, anxiety, depressed mood;
  • numbness or tingly feeling; or
  • pain or swelling where the medicine was injected.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about testosterone injection?

This medication can cause birth defects in an unborn baby if it is used by a woman during pregnancy. Do not receive testosterone injection if you are pregnant. Use an effective form of birth control, and tell your doctor if you become pregnant during treatment.

Do not receive this medication if you have prostate cancer, male breast cancer, if you are pregnant, or if you have ever had an allergic reaction to a hormone treatment.

Before receiving testosterone injection, tell your doctor if you have benign prostatic hypertrophy (BPH), a bleeding or blood clotting disorder, high cholesterol, any type of cancer, liver or kidney disease, or heart disease, coronary artery disease, or a history of heart attack.

Related Drug Centers
  • Depo-Testosterone


Related Drugs Index: