Tilade

DRUG DESCRIPTION

Tilade (nedocromil sodium) is an inhaled anti-inflammatory agent for the preventive management of asthma. Nedocromil sodium is a pyranoquinoline with the chemical name 4H-Pyrano[3,2-g]quinoline-2,8-dicarboxylic acid, 9-ethyl-6,9-dihydro-4,6-dioxo-10-propyl-, disodium salt, and it has a molecular weight of 415.3. The empirical formula is C19H15NNa2O7. Nedocromil sodium, a yellow powder, is soluble in water.

The molecular structure of nedocromil sodium is:

Tilade (nedocromil sodium) Structural Formula Illustration

Chemical Class: Pyranoquinoline

Tilade Inhaler (nedocromil sodium inhalation aerosol) is a pressurized metered-dose aerosol suspension for oral inhalation containing micronized nedocromil sodium and sorbitan trioleate, as well as dichlorotetrafluoroethane and dichlorodifluoromethane as propellants. Each Tilade canister contains 210 mg nedocromil sodium. Each actuation meters 2.00 mg nedocromil sodium from the valve and delivers 1.75 mg nedocromil sodium from the mouthpiece. Each 16.2 g canister provides at least 104 metered actuations. After 104 metered actuations, the amount delivered per actuation may not be consistent and the unit should be discarded.

Each Tilade (nedocromil inhalation aerosol) Inhaler canister must be primed with 3 actuations prior to the first use. If a canister remains unused for more than 7 days, then it should be reprimed with 3 actuations.

What are the possible side effects of nedocromil inhalation (Tilade)?

Serious side effects from nedocromil inhalation are not likely to occur. Seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives).

Other, less serious side effects may be more likely to occur. Continue to use nedocromil inhalation and talk to your doctor if you experience

  • a dry mouth,
  • an unpleasant taste, or
  • mild nausea after use.

Side effects other than those listed...

Read All Potential Side Effects and See Pictures of Tilade

What are the precautions when taking nedocromil inhalation aerosol (Tilade)?

Consult your...

Read All Potential Precautions of Tilade


Tilade Consumer (continued)

SIDE EFFECTS: Consult your pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS: Consult your pharmacist.


Tilade Patient Information Including Side Effects

Brand Names: Tilade

Generic Name: nedocromil inhalation (Pronunciation: neh DOK ra mill)

  • What is nedocromil inhalation (Tilade)?
  • What are the possible side effects of nedocromil inhalation (Tilade)?
  • What is the most important information I should know about nedocromil inhalation (Tilade)?
  • What should I discuss with my healthcare provider before using nedocromil inhalation (Tilade)?
  • How should I use nedocromil inhalation (Tilade)?
  • What happens if I miss a dose (Tilade)?
  • What happens if I overdose (Tilade)?
  • What should I avoid while using nedocromil inhalation (Tilade)?
  • What other drugs will affect nedocromil inhalation (Tilade)?
  • Where can I get more information?

What is nedocromil inhalation (Tilade)?

Nedocromil is an anti-inflammatory medication. It works by preventing the release of substances in the body that cause inflammation.

Nedocromil inhalation is used to prevent asthma attacks and other conditions involving inflammation of the lung tissues.

Nedocromil may also be used for purposes other than those listed in this medication guide.

What are the possible side effects of nedocromil inhalation (Tilade)?

Serious side effects from nedocromil inhalation are not likely to occur. Seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives).

Other, less serious side effects may be more likely to occur. Continue to use nedocromil inhalation and talk to your doctor if you experience

  • a dry mouth,
  • an unpleasant taste, or
  • mild nausea after use.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What is the most important information I should know about nedocromil inhalation (Tilade)?

Nedocromil inhalation will not stop an asthma attack that has already started. It is used to prevent attacks.

Do not use more of this medication than is prescribed for you. Too much may cause serious side effects.

Use nedocromil inhalation on a regular basis for best results. It may be one week or longer before you obtain the maximum benefit of this medication.

It is very important that you use your nedocromil inhaler properly, so that the medicine gets into your lungs. Your doctor may want you to use a spacer with your inhaler. Talk to your doctor about proper inhaler use.

Seek medical attention if you notice that you require more than your usual or more than the maximum amount of an asthma medication in a 24-hour period. An increased need for medication could be an early sign of a serious asthma attack.

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