Tekturna

DRUG DESCRIPTION

Tekturna contains aliskiren hemifumarate, a renin inhibitor, that is provided as tablets for oral administration. Aliskiren hemifumarate is chemically described as (2S,4S,5S,7S)-N-(2-carbamoyl-2-methylpropyl)-5-amino-4-hydroxy-2,7-diisopropyl-8-[4-methoxy-3-(3-methoxypropoxy)phenyl]-octanamide hemifumarate and its structural formula is

Tekturna*
  (aliskiren) tablets Structural Formula Illustration

Molecular formula: C30H53N3O6 0.5 C4H4O4

Aliskiren hemifumarate is a white to slightly yellowish crystalline powder with a molecular weight of 609.8 (free base-551.8). It is soluble in phosphate buffer, n-octanol, and highly soluble in water.

What are the possible side effects of aliskiren (Tekturna)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; severe stomach pain; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • feeling light-headed, fainting;
  • nausea with slow uneven heart rate and a weak pulse; or
  • swelling around your eyes.

Less serious side effects may be more likely to occur, such as:

  • stomach pain or upset, diarrhea,...

Read All Potential Side Effects and See Pictures of Tekturna

What are the precautions when taking aliskiren tablets (Tekturna)?

Before taking aliskiren, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: diabetes, gout, heart problems, kidney disease (including kidney stones).

Before having surgery, tell your doctor or dentist that you are taking this medication.

This medication is not recommended for use during pregnancy due to the risk for harm to an unborn baby. Consult your doctor for more details. (See also Warning section.)

It is not known whether this drug passes into breast milk. Consult your...

Read All Potential Precautions of Tekturna


Tekturna Consumer (continued)

SIDE EFFECTS: Upset stomach, diarrhea, lightheadedness, or cough may occur as your body adjusts to the medication. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

To lower your risk of lightheadedness, get up slowly when rising from a sitting or lying position.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Seek immediate medical attention if this rare but very serious side effect occurs: seizure.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any of the following symptoms of a serious allergic reaction: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS: Before taking aliskiren, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: diabetes, gout, heart problems, kidney disease (including kidney stones).

Before having surgery, tell your doctor or dentist that you are taking this medication.

This medication is not recommended for use during pregnancy due to the risk for harm to an unborn baby. Consult your doctor for more details. (See also Warning section.)

It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.


Tekturna Patient Information Including Side Effects

Brand Names: Tekturna

Generic Name: aliskiren (Pronunciation: a LIS ke rin)

  • What is aliskiren (Tekturna)?
  • What are the possible side effects of aliskiren (Tekturna)?
  • What is the most important information I should know about aliskiren (Tekturna)?
  • What should I discuss with my health care provider before taking aliskiren (Tekturna)?
  • How should I take aliskiren (Tekturna)?
  • What happens if I miss a dose (Tekturna)?
  • What happens if I overdose (Tekturna)?
  • What should I avoid while taking aliskiren (Tekturna)?
  • What other drugs will affect aliskiren (Tekturna)?
  • Where can I get more information?

What is aliskiren (Tekturna)?

Aliskiren is an anti-hypertensive (blood pressure lowering) medication. It works by decreasing substances in the body that narrow blood vessels and raise blood pressure.

Aliskiren is used to treat high blood pressure (hypertension).

Aliskiren may also be used for purposes other than those listed in this medication guide.

What are the possible side effects of aliskiren (Tekturna)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; severe stomach pain; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • feeling light-headed, fainting;
  • nausea with slow uneven heart rate and a weak pulse; or
  • swelling around your eyes.

Less serious side effects may be more likely to occur, such as:

  • stomach pain or upset, diarrhea, heartburn;
  • itching or skin rash;
  • headache, dizziness, tired feeling;
  • back pain, joint pain or swelling; or
  • stuffy nose, sore throat, cough.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about aliskiren (Tekturna)?

Do not use this medication without telling your doctor if you are pregnant or planning a pregnancy. Aliskiren could cause birth defects in the baby if you take the medication during pregnancy, especially during the last 6 months. Use an effective form of birth control. Stop using this medication and tell your doctor right away if you become pregnant during treatment.

Before you take aliskiren, tell your doctor if you have kidney disease, gout, diabetes, heart disease, or if you are on a low-salt diet.

If you take aliskiren with meals, avoid high-fat foods. They can make it harder for your body to absorb aliskiren.

Some things can cause your blood pressure to get too low. This includes vomiting, diarrhea, heavy sweating, heart disease, dialysis, a low-salt diet, or taking diuretics (water pills). Follow your doctor's instructions about the type and amount of liquids you should drink while taking aliskiren. Tell your doctor if you have a prolonged illness that causes diarrhea or vomiting.

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