TriLyte

DRUG DESCRIPTION

TriLyte (peg-3350, sodium chloride, sodium bicarbonate and potassium chloride) ® is a white powder for reconstitution containing 420 g polyethylene glycol 3350, 5.72 g sodium bicarbonate, 11.2 g sodium chloride, 1.48 g potassium chloride. Flavor packs, each containing 3.22 g of flavoring ingredients, are attached to the 4 liter bottle. See individual flavor packs for complete listing of ingredients. When dissolved in water to a volume of 4 liters, TriLyte (peg-3350, sodium chloride, sodium bicarbonate and potassium chloride) ® with flavor packs (PEG-3350, sodium chloride, sodium bicarbonate and potassium chloride for oral solution) is an isosmotic solution, for oral administration, having a pleasant mineral water taste. One flavor pack can be added before reconstitution to flavor the solution. TriLyte® with flavor packs (peg-3350, sodium chloride, sodium bicarbonate and potassium chloride) is administered orally or via nasogastric tube as a gastrointestinal lavage.

What are the possible side effects of polyethylene glycol electrolyte solution?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor if you have any of these serious side effects:

  • severe stomach pain or bloating;
  • no bowel movement within 2 hours after use; or
  • gagging, choking, or vomiting.

If you have any of these side effects, you may need to drink the medication more slowly, or stop using it for a short time.

Less...

Read All Potential Side Effects and See Pictures of TriLyte »

What are the precautions when taking peg-3350, sodium chloride, sodium bicarbonate and potassium chloride (TriLyte)?

Before taking electrolyte with PEG, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: certain stomach/intestinal problems (such as toxic colitis, obstruction).

Before using this medication, tell your doctor or pharmacist your medical history, especially of: severe ulcers/swelling of the colon (ulcerative colitis), trouble swallowing (such as poor gag reflex, aspiration), history of vomiting easily/often.

Special caution should be taken...

Read All Potential Precautions of TriLyte »


TriLyte Consumer (continued)

SIDE EFFECTS: Nausea, bloating, or feelings of fullness in the stomach/abdomen are very common. Stomach/abdominal cramps, vomiting, and anal irritation occur less often. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately if any of these rare but very serious side effects occur: vomit that is bloody or looks like coffee grounds, chest pain, fainting, sudden shortness of breath.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS: Before taking electrolyte with PEG, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: certain stomach/intestinal problems (such as toxic colitis, obstruction).

Before using this medication, tell your doctor or pharmacist your medical history, especially of: severe ulcers/swelling of the colon (ulcerative colitis), trouble swallowing (such as poor gag reflex, aspiration), history of vomiting easily/often.

Special caution should be taken if this medication is given to an unconscious or partly conscious person.

Caution is advised when using this drug in children because they may be more sensitive to its effects, especially dehydration. Room temperature solution is better for infants. Children younger than 2 years may be more likely to develop low blood sugar from not eating. Seek immediate medical attention if you notice symptoms of low blood sugar in your child, such as shakiness, unusual sleepiness, abnormal/prolonged crying.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.


TriLyte Patient Information Including Side Effects

Brand Names: Colyte, Colyte with Flavor Packs, GoLYTELY, MoviPrep, NuLYTELY, NuLYTELY Cherry, NuLYTELY Lemon Lime, NuLYTELY Orange, NuLYTELY with Flavor Packs, PEG-3350 with Electolytes, TriLyte with Flavor Packs

Generic Name: polyethylene glycol electrolyte solution (Pronunciation: pall ee ETH il een GLYE kol ee LEK troe lyte)

  • What is polyethylene glycol electrolyte solution (TriLyte)?
  • What are the possible side effects of polyethylene glycol electrolyte solution?
  • What is the most important information I should know about polyethylene glycol electrolyte solution?
  • What should I discuss with my health care provider before taking polyethylene glycol electrolyte solution?
  • How should I take polyethylene glycol electrolyte solution?
  • What happens if I miss a dose?
  • What happens if I overdose?
  • What should I avoid while taking polyethylene glycol electrolyte solution?
  • What other drugs will affect polyethylene glycol electrolyte solution?
  • Where can I get more information?

What is polyethylene glycol electrolyte solution (TriLyte)?

Polyethylene glycol electrolyte solution is a laxative solution that increases the amount of water in the intestinal tract to stimulate bowel movements. This medication also contains potassium, sodium, and other minerals to replace electrolytes that are passed from the body in the stool.

Polyethylene glycol electrolyte solution is used to clean the bowel before colonoscopy, a barium x-ray, or other intestinal procedures.

Polyethylene glycol electrolyte solution may also be used for purposes other than those listed in this medication guide.

What are the possible side effects of polyethylene glycol electrolyte solution?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor if you have any of these serious side effects:

  • severe stomach pain or bloating;
  • no bowel movement within 2 hours after use; or
  • gagging, choking, or vomiting.

If you have any of these side effects, you may need to drink the medication more slowly, or stop using it for a short time.

Less serious side effects may include:

  • mild stomach cramps, gas, or bloating;
  • rectal pain or irritation;
  • nausea; or
  • passing gas.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about polyethylene glycol electrolyte solution?

Do not use this medication if you are allergic to polyethylene glycol or any other electrolyte solutions (such as Pedialyte or Gatorade).

You should also not take polyethylene glycol electrolyte solution if you have a perforated bowel, a bowel obstruction or severe constipation, or colitis or toxic megacolon. If you have any these conditions, you could have dangerous or life-threatening side effects from polyethylene glycol electrolyte solution.

People with eating disorders (such as anorexia or bulimia) should not take polyethylene glycol electrolyte solution without the advice of a doctor.

Talk to your healthcare provider if you are not able to consume all of the solution. Incomplete cleansing of the bowel may affect the scheduled procedure.

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