Tigan

DRUG DESCRIPTION

Chemically, trimethobenzamide HCl is N-[p-[2-(dimethylamino)ethoxy]benzyl]-3,4,5trimethoxybenzamide monohydrochloride. It has a molecular weight of 424.93 and the following structural formula:

Tigan® (trimethobenzamide hydrochloride)   Structural Formula Illustration

Capsules: Each 300-mg Tigan (trimethobenzamide hydrochloride capsules) capsule for oral use contains trimethobenzamide hydrochloride equivalent to 300 mg. The capsule has an opaque purple cap marked “Tigan (trimethobenzamide hydrochloride capsules) ” and an opaque purple body marked “M079”. Inactive Ingredients: D&C Red No. 28, FD&C Blue No. 1, lactose, magnesium stearate, starch and titanium dioxide.

What are the possible side effects of trimethobenzamide (Tigan)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have any of these serious side effects:

  • jaundice (yellowing of the skin or eyes);
  • seizure (convulsions);
  • easy bruising or bleeding, unusual weakness;
  • tremor (uncontrolled shaking); or
  • muscle cramps, severe muscle spasms.

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Read All Potential Side Effects and See Pictures of Tigan »

What are the precautions when taking trimethobenzamide hydrochloride capsules (Tigan)?

Before taking trimethobenzamide, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: high fever, kidney problems, stomach/intestinal problems (e.g., appendicitis), swelling/disease of the brain (encephalitis/encephalopathy), a serious loss of body water (dehydration), mineral (electrolyte) imbalance.

This drug may make you dizzy or drowsy or cause blurred vision. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such...

Read All Potential Precautions of Tigan »


Tigan Consumer (continued)

SIDE EFFECTS: Diarrhea, headache, dizziness, drowsiness, blurred vision, or muscle cramps may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately if any of these unlikely but serious side effects occur: confusion, muscle spasms, unusual uncontrolled movements (especially of the face, mouth, tongue, arms, or legs), shaking (tremor), restlessness, drooling.

Tell your doctor immediately if any of these rare but very serious side effects occur: severe arching of the back, mouth sores, unusual bleeding/bruising, seizures, mental/mood changes (e.g., depression), yellowing eyes/skin, dark urine.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS: Before taking trimethobenzamide, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: high fever, kidney problems, stomach/intestinal problems (e.g., appendicitis), swelling/disease of the brain (encephalitis/encephalopathy), a serious loss of body water (dehydration), mineral (electrolyte) imbalance.

This drug may make you dizzy or drowsy or cause blurred vision. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely. Limit alcoholic beverages.

Kidney function declines as you grow older. This medication is removed by the kidneys. Therefore, older adults may be more sensitive to the effects of this drug.

Children and teenagers should not use this drug if they have chickenpox, flu, or any undiagnosed illness without first consulting a doctor about Reye's syndrome.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.


Tigan Patient Information Including Side Effects

Brand Names: Tigan

Generic Name: trimethobenzamide (Pronunciation: trye METH oh BENZ a mide)

  • What is trimethobenzamide (Tigan)?
  • What are the possible side effects of trimethobenzamide (Tigan)?
  • What is the most important information I should know about trimethobenzamide (Tigan)?
  • What should I discuss with my healthcare provider before taking trimethobenzamide (Tigan)?
  • How should I take trimethobenzamide (Tigan)?
  • What happens if I miss a dose (Tigan)?
  • What happens if I overdose (Tigan)?
  • What should I avoid while taking trimethobenzamide (Tigan)?
  • What other drugs will affect trimethobenzamide (Tigan)?
  • Where can I get more information?

What is trimethobenzamide (Tigan)?

Trimethobenzamide affects the areas of the brain that stimulate nausea and vomiting.

Trimethobenzamide is used to treat nausea and vomiting.

Trimethobenzamide may also be used for purposes other than those listed in this medication guide.

What are the possible side effects of trimethobenzamide (Tigan)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have any of these serious side effects:

  • jaundice (yellowing of the skin or eyes);
  • seizure (convulsions);
  • easy bruising or bleeding, unusual weakness;
  • tremor (uncontrolled shaking); or
  • muscle cramps, severe muscle spasms.

Continue using trimethobenzamide and talk with your doctor if you have any of these less serious side effects:

  • drowsiness or dizziness;
  • headache;
  • feeling depressed or disoriented; or
  • blurred vision.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about trimethobenzamide (Tigan)?

Seek emergency medical attention if you think you have used too much of this medicine. Symptoms of a trimethobenzamide overdose may include drowsiness, uncontrollable movements, muscle spasms, blurred vision, seizures or convulsions, difficulty breathing, and death.

Trimethobenzamide may increase the side effects of other drugs that make you sleepy (such as alcohol, cold medicine, pain medication, muscle relaxants, and medicine for seizures, depression or anxiety). Before using trimethobenzamide, tell your doctor if you are using any of these medicines.

Trimethobenzamide can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid drinking alcohol while you are using trimethobenzamide. Alcohol may increase drowsiness and dizziness.

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